Results 11 to 20 of about 220,180 (319)

Nucleophosmin3 carried by small extracellular vesicles contribute to white adipose tissue browning [PDF]

open access: yesJournal of Nanobiotechnology, 2022
Background Browning of white adipose tissue (WAT) is a particularly appealing target for therapeutics in the treatment of obesity and related metabolic diseases.
Yan Zhang   +4 more
doaj   +2 more sources

LLTH induces white adipose tissue browning via NF κB inhibition in ATM [PDF]

open access: yesScientific Reports
This study aimed to explore the role of macrophage polarization and TLR4/NF-κB pathway in promoting browning of white adipose tissue through different hypoxic exercises.
Yingli Lu   +4 more
doaj   +2 more sources

PRMT4 Facilitates White Adipose Tissue Browning and Thermogenesis by Methylating PPARγ

open access: yesDiabetes, 2023
Obesity is a global health threat, and the induction of white adipose tissue (WAT) browning presents a promising therapeutic method for it. Recent publications revealed the essential role of protein arginine methyltransferase 4 (PRMT4) in lipid ...
Yi Zhong   +11 more
semanticscholar   +1 more source

Lytic cocktail: An effective method to alleviate severe burn induced hyper-metabolism through regulating white adipose tissue browning

open access: yesHeliyon, 2022
Background: Browning of white adipose tissue is associated with elevated resting metabolic rates and is considered to be one of the indispensable causes of hypermetabolism in burn patients.
Meng Zhang   +8 more
doaj   +1 more source

An immune-sympathetic neuron communication axis guides adipose tissue browning in cancer-associated cachexia

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2022
Significance More than a half of cancer patients suffer a complex metabolic syndrome termed cancer-associated cachexia (CAC). This disorder is characterized by unintended loss of body weight and largely reduces quality of life, effectiveness of ...
Hao Xie   +16 more
semanticscholar   +1 more source

Browning of the white adipose tissue regulation: new insights into nutritional and metabolic relevance in health and diseases

open access: yesNutrition & Metabolism, 2022
Adipose tissues are dynamic tissues that play crucial physiological roles in maintaining health and homeostasis. Although white adipose tissue and brown adipose tissue are currently considered key endocrine organs, they differ functionally and ...
Sabrina Azevedo Machado   +6 more
doaj   +1 more source

Adipose tissue browning and thermogenesis under physiologically energetic challenges: a remodelled thermogenic system

open access: yesJournal of Physiology, 2023
Metabolic diseases such as obesity and diabetes are often thought to be caused by reduced energy expenditure, which poses a serious threat to human health. Cold exposure, exercise and caloric restriction have been shown to promote adipose tissue browning
Yupeng Zhu, Weina Liu, Zhengtang Qi
semanticscholar   +1 more source

Genistein improves glucose metabolism and promotes adipose tissue browning through modulating gut microbiota in mice.

open access: yesFood & Function, 2022
Genistein has beneficial effects on glucose metabolism and adipose tissue browning which paralleled with gut microbiota alterations. However, the causality is unclear. This study aims to evaluate whether genistein could ameliorate metabolism and activate
Shunhua Li   +4 more
semanticscholar   +1 more source

Green Tea Induces the Browning of Adipose Tissue—Systematic Review

open access: yesObesities, 2023
Several foods and nutrients are being studied extensively because they have a positive effect on thermogenesis and the browning of white adipose tissue.
Ana Paula Azevêdo Macêdo   +8 more
doaj   +1 more source

Beta‐adrenergic agonist induces unique transcriptomic signature in inguinal white adipose tissue

open access: yesPhysiological Reports, 2023
Activation of thermogenic adipose tissue depots has been linked to improved metabolism and weight loss. To study the molecular regulation of adipocyte thermogenesis, we performed RNA‐Seq on brown adipose tissue (BAT), gonadal white adipose tissue (gWAT),
Henry A. Paz   +5 more
doaj   +1 more source

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