Results 51 to 60 of about 220,180 (319)
Adipose tissue browning in mice and humans
Journal of Endocrinology, 2019 In the midst of an obesity epidemic, the promotion of brown adipose tissue (BAT) function and the browning of white adipose tissue (WAT) have emerged as promising therapeutic targets to increase energy expenditure and counteract weight gain.
C. Herz, F. Kiefer
semanticscholar +1 more source
Frontiers in Endocrinology, 2023 Overweight and obesity have become a world-wide problem. However, effective intervention approaches are limited. Brown adipose tissue, which helps maintain body temperature and contributes to thermogenesis, is dependent on uncoupling protein1.
Xiaomeng Liu +7 more
doaj +1 more source
Metabolic effects of FGF-21: thermoregulation and beyond [PDF]
, 2015 Fibroblast growth factor (FGF)-21, a member of the FGF family, is a novel hormone involved in the control of metabolism by modulating glucose homeostasis, insulin sensitivity, ketogenesis, and promoting adipose tissue “browning.” Recent studies ...
Celi, Francesco S. +3 more
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Regulation of tissue crosstalk by skeletal muscle-derived myonectin and other myokines. [PDF]
, 2012 The integrated control of animal physiology requires intimate tissue crosstalk, a vital task mediated by circulating humoral factors. As one type of these factors, adipose tissue-derived adipokines have recently garnered attention as important regulators
Seldin, Marcus M, Wong, G William
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Brown adipose tissue and bone [PDF]
International Journal of Obesity Supplements, 2015 Brown adipose tissue (BAT) is capable of transforming chemically stored energy, in the form of triglycerides, into heat. Recent studies have shown that metabolically active BAT is present in a large proportion of adult humans, where its activity correlates with a favorable metabolic status. Hence, the tissue is now regarded as an interesting target for
M E, Lidell, S, Enerbäck
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Cell Reports, 2015 The functional conversion of white adipose tissue (WAT) into a tissue with brown adipose tissue (BAT)-like activity, often referred to as “browning,” represents an intriguing strategy for combating obesity and metabolic disease.
Jean Z. Lin +10 more
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Tbx15 is required for adipocyte browning induced by adrenergic signaling pathway
Molecular Metabolism, 2019 Objective: The T-box gene Tbx15 is abundantly expressed in adipose tissues, especially subcutaneous and brown fat. Although its expression is correlated with obesity, its precise biological role in adipose tissue is poorly understood in vivo.
Wei Sun +16 more
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Irisin evokes bradycardia by activating cardiac-projecting neurons of nucleus ambiguus. [PDF]
, 2015 Irisin is a newly identified hormone induced in muscle and adipose tissues by physical activity. This protein and its encoding gene have been identified in the brain; in addition, the precursor for irisin, FNDC5, can cross the blood-brain barrier.
Brailoiu, Eugen +3 more
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Deceptive Brown Adipose Tissue
Journal of the ASEAN Federation of Endocrine SocietiesA 23-year-old female presented with headache, palpitation, and hypertensive spells. There was no similar family history. Twenty-four (24) hour urine testing showed elevated normetanephrine level with normal metanephrines [metanephrines 123 mcg/24 hrs (74-297); normetanephrines 5321.16 mcg/24 hrs (73-808)].
Biswajit Payra +4 more
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FEBS Open Bio, EarlyView.Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source