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Antigen-Dependent Adjuvanticity of Poly(lactic-co-glycolic acid)-polyethylene Glycol 25% Nanoparticles for Enhanced Vaccine Efficacy [PDF]

open access: yesVaccines
Background: A key component in modern vaccine development is the adjuvant, which enhances and/or modulates the antigen-specific immune response. In recent years, nanoparticle (NP)-based adjuvants have attracted much research attention owing to their ...
Minxuan Cui   +8 more
doaj   +2 more sources

Mathematical Modelling of Hydrophilic Ionic Fertiliser Diffusion in Plant Cuticles: Lipophilic Surfactant Effects [PDF]

open access: yes, 2019
The agricultural industry requires improved efficacy of sprays being applied to crops and weeds to reduce their environmental impact and increase financial returns. One way to improve efficacy is by enhancing foliar penetration. The plant leaf cuticle is
Farrell, Troy W.   +2 more
core   +2 more sources

Outer Membrane Vesicles: Current Status and Future Direction of These Novel Vaccine Adjuvants

open access: yesFrontiers in Microbiology, 2018
Adjuvants have been of great interest to vaccine formulation as immune-stimulators. Prior to the recent research in the field of immune stimulation, conventional adjuvants utilized for aluminum-based vaccinations dominated the adjuvant market.
Qiong Liu, Xiaotian Huang
exaly   +3 more sources

Basic Properties and Development Status of Aluminum Adjuvants Used for Vaccines [PDF]

open access: yesVaccines
Background: Aluminum adjuvants, renowned for their safety and efficacy, act as excellent adsorbents and vaccine immunogen enhancers, significantly contributing to innate, endogenous, and humoral immunity.
Jingyang Lan   +4 more
doaj   +2 more sources

Progress and prospect of polysaccharides as adjuvants in vaccine development [PDF]

open access: yesVirulence
Vaccines are an effective approach to confer immunity against infectious diseases. Modern subunit vaccines offer more precise target and safe protection compared to traditional whole-pathogen vaccines.
Xinlong Liang   +6 more
doaj   +2 more sources

Vaccine Adjuvants: Selection Criteria, Mechanism of Action Associated with Immune Responses and Future Directions [PDF]

open access: yesIranian Journal of Immunology, 2023
The most effective method to minimize the prevalence of infectious diseases is vaccination. Vaccines enhance immunity and provide protection against different kinds of infections.
Arslan Habib   +10 more
doaj   +1 more source

Research Progress of Aluminum Phosphate Adjuvants and Their Action Mechanisms

open access: yesPharmaceutics, 2023
Although hundreds of different adjuvants have been tried, aluminum-containing adjuvants are by far the most widely used currently. It is worth mentioning that although aluminum-containing adjuvants have been commonly applied in vaccine production, their ...
Ting Zhang   +5 more
doaj   +1 more source

Adjuvantation of Influenza Vaccines to Induce Cross-Protective Immunity

open access: yesVaccines, 2021
Influenza poses a huge threat to global public health. Influenza vaccines are the most effective and cost-effective means to control influenza. Current influenza vaccines mainly induce neutralizing antibodies against highly variable globular head of ...
Zhuofan Li   +3 more
doaj   +1 more source

Antibiotic adjuvants: synergistic tool to combat multi-drug resistant pathogens

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
The rise of multi-drug resistant (MDR) pathogens poses a significant challenge to the field of infectious disease treatment. To overcome this problem, novel strategies are being explored to enhance the effectiveness of antibiotics.
Vikram Kumar   +10 more
doaj   +1 more source

Current status and prospect for development of COVID-19 vaccine adjuvants

open access: yes陆军军医大学学报, 2022
Vaccines are the most economical and effective means to protect against SARS-CoV-2 infection. Adjuvants are able to enhance antigen-specific immune responses, reduce antigen doses and vaccination times, and reshape adaptive immune responses, which are ...
LI Haibo, CHENG Hao
doaj   +1 more source

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