Mechanisms of Action of Adjuvants [PDF]
Frontiers in Immunology, 2013 Adjuvants are used in many vaccines, but their mechanisms of action are not fully understood. Studies from the past decade on adjuvant mechanisms are slowly revealing the secrets of adjuvant activity.
Sunita eAWATE +2 more
exaly +6 more sources
The recent advances in vaccine adjuvants [PDF]
Frontiers in ImmunologyVaccine adjuvants, as key components in enhancing vaccine immunogenicity, play a vital role in modern vaccinology. This review systematically examines the historical evolution and mechanisms of vaccine adjuvants, with particular emphasis on innovative ...
Jiayin Xing +6 more
doaj +2 more sources
Mathematical Modelling of Hydrophilic Ionic Fertiliser Diffusion in Plant Cuticles: Lipophilic Surfactant Effects [PDF]
, 2019 The agricultural industry requires improved efficacy of sprays being applied to crops and weeds to reduce their environmental impact and increase financial returns. One way to improve efficacy is by enhancing foliar penetration. The plant leaf cuticle is the most significant barrier to agrochemical diffusion within the leaf.
Farrell, Troy W. +2 more
arxiv +3 more sources
Antigen-Dependent Adjuvanticity of Poly(lactic-co-glycolic acid)-polyethylene Glycol 25% Nanoparticles for Enhanced Vaccine Efficacy [PDF]
VaccinesBackground: A key component in modern vaccine development is the adjuvant, which enhances and/or modulates the antigen-specific immune response. In recent years, nanoparticle (NP)-based adjuvants have attracted much research attention owing to their ...
Minxuan Cui +8 more
doaj +2 more sources
Harnessing adjuvant-induced epigenetic modulation for enhanced immunity in vaccines and cancer therapy [PDF]
Frontiers in ImmunologyAdjuvants are crucial in vaccines and cancer therapies, enhancing therapeutic efficacy through diverse mechanisms. In vaccines, adjuvants are traditionally valued for amplifying immune responses, ensuring robust and long-lasting protection against ...
Yasmine Megdiche +1 more
doaj +2 more sources
Outer Membrane Vesicles: Current Status and Future Direction of These Novel Vaccine Adjuvants
Frontiers in Microbiology, 2018 Adjuvants have been of great interest to vaccine formulation as immune-stimulators. Prior to the recent research in the field of immune stimulation, conventional adjuvants utilized for aluminum-based vaccinations dominated the adjuvant market.
Qiong Liu, Xiaotian Huang
exaly +3 more sources
Vaccine Adjuvants: Selection Criteria, Mechanism of Action Associated with Immune Responses and Future Directions [PDF]
Iranian Journal of Immunology, 2023 The most effective method to minimize the prevalence of infectious diseases is vaccination. Vaccines enhance immunity and provide protection against different kinds of infections.
Arslan Habib +10 more
doaj +1 more source
Research Progress of Aluminum Phosphate Adjuvants and Their Action Mechanisms
Pharmaceutics, 2023 Although hundreds of different adjuvants have been tried, aluminum-containing adjuvants are by far the most widely used currently. It is worth mentioning that although aluminum-containing adjuvants have been commonly applied in vaccine production, their ...
Ting Zhang +5 more
doaj +1 more source
Adjuvantation of Influenza Vaccines to Induce Cross-Protective Immunity
Vaccines, 2021 Influenza poses a huge threat to global public health. Influenza vaccines are the most effective and cost-effective means to control influenza. Current influenza vaccines mainly induce neutralizing antibodies against highly variable globular head of ...
Zhuofan Li +3 more
doaj +1 more source
Current status and prospect for development of COVID-19 vaccine adjuvants
陆军军医大学学报, 2022 Vaccines are the most economical and effective means to protect against SARS-CoV-2 infection. Adjuvants are able to enhance antigen-specific immune responses, reduce antigen doses and vaccination times, and reshape adaptive immune responses, which are ...
LI Haibo, CHENG Hao
doaj +1 more source