Results 161 to 170 of about 14,767 (273)

Editorial: Novel adjuvant systems that generate pathogen specific T cell responses following immunization for infectious disease vaccine formulations. [PDF]

Front Immunol
Burkhardt AM, Wang SW, Harandi AM.
europepmc   +1 more source

Rare‐Earth‐Based Nanomaterials for Cancer Therapy

Cancer Nexus, EarlyView.
This review highlights recent advances in cancer therapy using rare‐earth‐based nanomaterials (RENMs), covering applications such as fluorescent surgical tumor resection, light‐triggered therapy, enzyme‐catalyzed therapy, enhanced radiotherapy, and lanthanide‐coordinated nanoformulations.
Linshuo Gao, Yawei Liu, Kai Liu, Hongjie Zhang   +3 more
wiley   +1 more source

How do adjuvants enhance immune responses? [PDF]

Elife
Rapaka RR.
europepmc   +1 more source

Chlorogenic Acid: An In‐Depth Review of Its Effectiveness in Cancer Treatment

Cancer Nexus, EarlyView.
ABSTRACT Cancer remains a formidable global health challenge. Owing to the unsatisfactory curative effects and severe side effects, it is urgent to explore safer and more effective therapeutic alternatives and drugs. Chlorogenic acid (CGA), a natural polyphenol, has emerged as a promising candidate for cancer therapy due to its multiple functions and ...
Bin Wang, Na Yin, Xinrui Liu, Yang Bai, Yue Cao, Ziqian Wang, Shiqi Bai, Shaopeng Zhang, Wanying Li, Yinghui Wang   +9 more
wiley   +1 more source

Novel nanoemulsion adjuvant stabilized by TPGS possesses equivalent physicochemical properties, Turbiscan stability, and adjuvanticity to AS03 for eliciting robust immunogenicity of subunit vaccines in mice. [PDF]

Hum Vaccin Immunother
Yin Q, Song S, Liu Z.
europepmc   +1 more source

Advancements in the Application of the Intersection of Medicine and Engineering in Cancer Research

Cancer Nexus, EarlyView.
ABSTRACT Cancer research predominantly centers on diagnosis, treatment, and elucidation of underlying mechanisms. Nevertheless, the intricate nature of tumor genesis and development has rendered early diagnostic and therapeutic outcomes less than optimal, making tumor conquest a formidable challenge.
Haitao Chen, Guanmeng Zhang, Yuping Qian, Yang Peng, Xiaoli Li, Jiawen Wang, Jinlan Wang, Yuxiang Hu, Han Xiao, Qinqiu Zhong, Xin Li, Yumeng Xie, Yukun Chen, Lijun Zhao, Qiqi Jing, Xiaofeng Shan, Yuguang Wang   +16 more
wiley   +1 more source

Precision adjuvants for pediatric vaccines. [PDF]

Sci Transl Med
Singh A, Boggiano C, Yin DE, Polakowski L, Majji SP, Leitner WW, Levy O, De Paris K.   +7 more
europepmc   +1 more source

Night‐Time Chronotherapy with Methylprednisolone Prevents an Acute Rejection in Pediatric Patients with Liver Transplantation: A Randomized Clinical Trial

Clinical Pharmacology &Therapeutics, EarlyView.
Concept of methylprednisolone chronotherapy to prevent acute rejections. While endogenous cortisol secretion rises in the early morning, the number of lymphocytes in the blood is higher at night, thus exhibiting an antiphase pattern to cortisol secretion. Therefore, compared with the daytime, the infiltration of lymphocytes into immune‐reactive tissues
Kentaro Ushijima, Yukihiro Sanada, Shinya Otomo, Keiko Ogaki, Taiichi Wakiya, Noriki Okada, Yuta Hirata, Yasuharu Onishi, Yasunaru Sakuma, Yukiyo Wada, Akio Fujimura, Koichi Mizuta   +11 more
wiley   +1 more source

Harnessing immunotherapeutic molecules and diagnostic biomarkers as human-derived adjuvants for MERS-CoV vaccine development. [PDF]

Front Immunol
Alrasheed AR, Awadalla M, Alnajran H, Alammash MH, Almaqati AM, Qadri I, Alosaimi B.   +6 more
europepmc   +1 more source

Model‐Informed Drug Development Applications and Opportunities in mRNA‐LNP Therapeutics

Clinical Pharmacology &Therapeutics, EarlyView.
The utilization of lipid nanoparticles (LNP) for encapsulating mRNA has revolutionized the field of therapeutics, enabling the rapid development of COVID‐19 vaccines and cancer vaccines. However, the clinical development of mRNA‐LNP therapeutics faces numerous challenges due to their complex mechanisms of action and limited clinical experience.
Jiawei Zhou, Rohit Rao, Monica E. Shapiro, Nessy Tania, Cody Herron, Cynthia J. Musante, Jim H. Hughes   +6 more
wiley   +1 more source