Results 231 to 240 of about 21,384 (315)

Safety and Oncologic Outcomes of Endoscopic Endonasal Transcribriform Approach for Locally Advanced Sinonasal Malignancies

Head &Neck, EarlyView.
ABSTRACT Introduction The past two decades have seen a paradigm shift in the surgical treatment of sinonasal malignancies, moving from traditional open approaches to minimally invasive endoscopic techniques. Technological advancements have enabled the use of the endoscopic endonasal transcribriform approach (EETA) for tumors involving the anterior ...
Michel Khalaf, Héloïse De Kermadec, Juliette Hershkovitch, Odile Casiraghi, Gabriel Garcia, François Bidault, François‐Régis Ferrand, France Nguyen, Stéphane Temam, Pierre Blanchard, Damien Bresson, Antoine Moya Plana   +11 more
wiley   +1 more source

Sarcopenia Trajectories Predict Survival in Operable Head and Neck Cancer

Head &Neck, EarlyView.
ABSTRACT Background Sarcopenia is associated with increased treatment toxicity and survival in head and neck squamous cell cancer (HNSCC). This study evaluates sarcopenia trajectories and their association with overall survival (OS) and disease‐free survival (DFS) in operable HNSCC.
Marco A. Mascarella, Alex Mlynarek, Keith Richardson, Karen Kost, Anthony Zeitouni, Khalil Sultanem, Christina Tsien, George Shenouda, Nathaniel Bouganim, Khashayar Esfahani, Michael Hier, Nader Sadeghi, Marie‐Jeanne Kergoat   +12 more
wiley   +1 more source

First‐Line Therapy in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: A Retrospective, Multicenter, Real‐World Study

Head &Neck, EarlyView.
ABSTRACT Background In Europe, pembrolizumab with or without chemotherapy is the recommended first‐line treatment for recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC), with a combined positive score (CPS) ≥ 1. In France, the TPExtreme (TPEx) regimen is preferred for CPS < 1.
Alizée Simon, Cyril Abdeddaim, DucTrung Nguyen, Patrice Gallet, Didier Peiffert, Aurélien Lambert, Lionnel Geoffrois   +6 more
wiley   +1 more source

Pretreatment Neutrophil‐to‐Lymphocyte Ratio (NLR) Predicts Treatment Toxicity and Intolerance in Operable Head and Neck Cancer: An Ambispective Cohort Study

Head &Neck, EarlyView.
ABSTRACT Background Pretreatment neutrophil to lymphocyte ratio (NLR) is a negative prognostic marker for survival in head and neck cancer (HNC). Its association with treatment toxicity and intolerance in patients undergoing curative‐intent surgery is unknown. Methods Ambispective study of patients with operable stage II–IV, HPV‐negative HNC treated at
Raisa Chowdhury, Karim Botros, Keith Richardson, Alex M. Mlynarek, Nader Sadeghi, Michael P. Hier, Sabrina Wurzba, Khashayar Esfahani, Nathaniel Bouganim, Khalil Sultanem, George Shenouda, Christina Tsien, Marco A. Mascarella   +12 more
wiley   +1 more source

<i>N</i>-2-Hydroxypropyl Trimethyl Ammonium Chloride Chitosan-Aluminum Nano-Adjuvant Elicit Strong Immune Responses in Porcine Epidemic Diarrhea Inactivated Vaccine. [PDF]

Int J Nanomedicine
Jin Z, Liu J, Guo S, Xu S, Gong X, Zhang C, Zhao K.   +6 more
europepmc   +1 more source

Age-related changes in the immune system and challenges for the development of age-specific vaccines. [PDF]

Ann Med
Doherty TM, Weinberger B, Didierlaurent A, Lambert PH.   +3 more
europepmc   +1 more source

Antigen-specific antibody Fc glycosylation enhances humoral immunity via the recruitment of complement [PDF]

, 2018
Diamond, Michael S, et al,, Fox, Julie M
core   +1 more source

Therapeutic targeting of chromatin alterations in leukemia and solid tumors

International Journal of Cancer, EarlyView.
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner, Tobias Berg, Daniel Sasca, Sophie‐Luise Mersiowsky, Jayant Y. Gadrey, Johanna Thomas, Michael W. M. Kühn, Michael Lübbert   +7 more
wiley   +1 more source

Invited Perspective: The Far Reach of PFAS-Inert Ingredients and Adjuvants in Pesticide Formulations. [PDF]

Environ Health Perspect
Sehgal N, Barr DB, Eick SM.
europepmc   +1 more source

Blood‐based biomarkers in soft tissue sarcoma: Implications for immune checkpoint inhibitor therapy

International Journal of Cancer, EarlyView.
Abstract Soft tissue sarcoma (STS) is a rare and heterogeneous cancer, comprising approximately 1% of all adult cancers and 7%–15% of all childhood cancers. In the advanced stages, chemotherapy remains the standard‐of‐care, but efficacy is limited, with a response rate of 15%–30%, and responses are often short‐lived, with median progression‐free ...
Brie‐Anne Mannah, John J. Park, Su Yin Lim   +2 more
wiley   +1 more source