Results 11 to 20 of about 531,871 (379)
New-age vaccine adjuvants, their development, and future perspective
Frontiers in Immunology, 2023 In the present scenario, immunization is of utmost importance as it keeps us safe and protects us from infectious agents. Despite the great success in the field of vaccinology, there is a need to not only develop safe and ideal vaccines to fight deadly ...
Shailendra Kumar Verma +6 more
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Vaccine adjuvants: mechanisms and platforms
Signal Transduction and Targeted Therapy, 2023 Adjuvants are indispensable components of vaccines. Despite being widely used in vaccines, their action mechanisms are not yet clear. With a greater understanding of the mechanisms by which the innate immune response controls the antigen-specific ...
Tingmei Zhao +6 more
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Exploration of Pattern Recognition Receptor Agonists as Candidate Adjuvants
Frontiers in Cellular and Infection Microbiology, 2021 Adjuvants are used to maximize the potency of vaccines by enhancing immune reactions. Components of adjuvants include pathogen-associated molecular patterns (PAMPs) and damage-associate molecular patterns (DAMPs) that are agonists for innate immune ...
Guang Han Ong +3 more
doaj +2 more sources
Selection of adjuvants for vaccines targeting specific pathogens
Expert Review of Vaccines, 2019 Introduction: Adjuvants form an integral component in most of the inactivated and subunit vaccine formulations. Careful and proper selection of adjuvants helps in promoting appropriate immune responses against target pathogens at both innate and adaptive
Indranil Sarkar +2 more
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Emerging concepts in the science of vaccine adjuvants
Nature reviews. Drug discovery, 2021 Adjuvants are vaccine components that enhance the magnitude, breadth and durability of the immune response. Following its introduction in the 1920s, alum remained the only adjuvant licensed for human use for the next 70 years.
B. Pulendran +2 more
semanticscholar +1 more source
Antibiotic Adjuvants: A Versatile Approach to Combat Antibiotic Resistance
ACS Omega, 2023 The problem of antibiotic resistance is on the rise, with multidrug-resistant strains emerging even to the last resort antibiotics. The drug discovery process is often stalled by stringent cut-offs required for effective drug design.
G. Dhanda, Y. Acharya, J. Haldar
semanticscholar +1 more source
An Overview of Vaccine Adjuvants: Current Evidence and Future Perspectives
Vaccines, 2022 Vaccinations are one of the most important preventive tools against infectious diseases. Over time, many different types of vaccines have been developed concerning the antigen component.
A. Facciolà +3 more
semanticscholar +1 more source
Aluminum Adjuvants—‘Back to the Future’
Pharmaceutics, 2023 Aluminum-based adjuvants will continue to be a key component of currently approved and next generation vaccines, including important combination vaccines.
Donatello Laera +2 more
semanticscholar +1 more source
The advances of adjuvants in mRNA vaccines
npj Vaccines, 2023 The remarkable success of messenger RNA (mRNA) vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has propelled the rapid development of this vaccination technology in recent years. Over the last three decades, numerous studies
C. Xie, Ruhui Yao, Xiaojun Xia
semanticscholar +1 more source
Vaccines, 2023 Vaccination is the best way to prevent and reduce the damage caused by infectious diseases in animals and humans. So, several vaccines are used for prophylactic purposes before the pathogen infects, while therapeutic vaccines strengthen the immune system
Soren Nooraei +3 more
semanticscholar +1 more source