Exploration of Pattern Recognition Receptor Agonists as Candidate Adjuvants
Frontiers in Cellular and Infection Microbiology, 2021 Adjuvants are used to maximize the potency of vaccines by enhancing immune reactions. Components of adjuvants include pathogen-associated molecular patterns (PAMPs) and damage-associate molecular patterns (DAMPs) that are agonists for innate immune ...
Guang Han Ong +3 more
doaj +1 more source
A Retrospective Analysis using Deep-Learning Models for Prediction of Survival Outcome and Benefit of Adjuvant Chemotherapy in Stage II/III Colorectal Cancer [PDF]
arXiv, 2021 Most early-stage colorectal cancer (CRC) patients can be cured by surgery alone, and only certain high-risk early-stage CRC patients benefit from adjuvant chemotherapies. However, very few validated biomarkers are available to accurately predict survival benefit from postoperative chemotherapy.
arxiv
Effects of Adjuvants on Spraying Characteristics and Control Efficacy in Unmanned Aerial Application
Agriculture, 2022 Pesticide application by unmanned agricultural aerial vehicles (UAVs) has rapidly developed in China and other Asian counties. Currently, tank-mix spray adjuvants are usually added into pesticide solutions to reduce spray drift and facilitate droplet ...
Shilin Wang +6 more
doaj +1 more source
The type of adjuvant in whole inactivated influenza a virus vaccines impacts vaccine-associated enhanced respiratory disease [PDF]
, 2018 Influenza A virus (IAV) causes a disease burden in the swine industry in the US and is a challenge to prevent due to substantial genetic and antigenic diversity of IAV that circulate in pig populations.
Gauger, P C +7 more
core +1 more source
Vaccine Potentiation by Combination Adjuvants
Vaccines, 2014 Adjuvants are crucial components of vaccines. They significantly improve vaccine efficacy by modulating, enhancing, or extending the immune response and at the same time reducing the amount of antigen needed. In contrast to previously licensed adjuvants,
Benoît Levast +5 more
doaj +1 more source
General characteristics of adjuvants and their mechanisms of action (part 2)
Биопрепараты: Профилактика, диагностика, лечение, 2021 One of the major public health challenges today is development of new vaccines and technologies to optimize the vaccination process. There is a growing scientific interest in vaccine adjuvants that enhance vaccine immunogenicity.
N. А. Alpatova +5 more
doaj +1 more source
Gr1+IL-4-producing innate cells are induced in response to Th2 stimuli and suppress Th1-dependent antibody responses [PDF]
, 2008 Alum is used as a vaccine adjuvant and induces T<sub>h</sub>2 responses and T<sub>h</sub>2-driven antibody isotype production against co-injected antigens.
A. S. McKee +45 more
core +1 more source
Medicine in Drug Discovery, 2021 Adjuvants are essential components of vaccines that have been particularly effective at promoting protective humoral immunity to infectious diseases and preventing mortality and morbidity.
Zhenchuan Wu, Keqin Liu
doaj
Distinctive cellular response to aluminum based adjuvants. [PDF]
, 2020 Aluminum-based adjuvants (ABAs) are used in human vaccines to enhance the magnitude of protective immune responses elicited against specific pathogens.
Bondy, Stephen C +3 more
core
Local vaccination and systemic tumor suppression via irradiation and manganese adjuvant in mice [PDF]
arXiv, 2021 Presently 4T-1 luc cells were irradiated with proton under ultra-high dose rate FLASH or with gamma-ray with conventional dose rate, and then subcutaneous vaccination with or without Mn immuno-enhancing adjuvant into the mice for three times. One week later, we injected untreated 4T-1 luc cells on the other side of the vaccinated mice, and found that ...
arxiv