Results 31 to 40 of about 134,663 (283)

Adjuvant-induced autoimmune syndrome triggered by silicone breast implants: systematic review [PDF]

Revista Brasileira de Cirurgia Plástica, 2022
Adjuvant-induced autoimmune syndrome (ASIA) and its diagnostic criteria were described by Shoenfeld in 2011, relating symptoms of autoimmunity to adjuvants, such as silicone, present in breast implants.
Caio Munaretto Giacomazzo, Caroline Noda Sakai, Rayane Merlly Gandolfi de Araujo, Maria Cecilia Closs Ono, Alfredo Benjamin Duarte-da-Silva, Renato da Silva Freitas   +5 more
doaj   +1 more source

A vaccine formulated with the major outer membrane protein can protect C3H/HeN, a highly susceptible strain of mice, from a Chlamydia muridarum genital challenge. [PDF]

, 2015
C3H/HeN female mice were vaccinated with native Chlamydia muridarum major outer membrane protein (MOMP), using Montanide+CpG or Alum+CpG as adjuvants. Negative control groups were immunized with ovalbumin (OVA) and the same adjuvants. As positive control,
de la Maza, Luis M, Pal, Sukumar, Tatarenkova, Olga V   +2 more
core   +1 more source

Rational Combination of Dominant and Subdominant Antigens with Nanoadjuvant Elicits Durable Immunity Against Staphylococcus aureus

Vaccines
Objectives: In response to the challenge that Staphylococcus aureus (S. aureus) vaccines fail to induce durable protective immunity, this study aims to develop a novel antigen-adjuvant co-design strategy.
Zhuoyue Shi, Jiayue Xi, Minxuan Cui, Zhuo Wan, Yufei Hou, Zhengjun Ma, Nan Sun, Yupu Zhu, Muqiong Li, Dong Wang, Xin He, Qian Yang, Chaojun Song, Li Fan   +13 more
doaj   +1 more source

Distinctive cellular response to aluminum based adjuvants. [PDF]

, 2020
Aluminum-based adjuvants (ABAs) are used in human vaccines to enhance the magnitude of protective immune responses elicited against specific pathogens.
Bondy, Stephen C, Campbell, Arezoo, Hidalgo, Krisha, Nies, Isaac   +3 more
core  

Characterization of potential biomarkers of reactogenicity of licensed antiviral vaccines: randomized controlled clinical trials conducted by the BIOVACSAFE consortium [PDF]

, 2019
Funding text The authors are grateful for the vital contributions of the participating study volunteers, clinicians, nurses, and laboratory technicians at the Surrey study site.
Bodinham, C., Bottazzi, B., DelGiudice, G., Denoel, P., Greenwood, A., Jonsdottir, I., Kaufmann, S., Kester, K., Leroux-Roels, G., Lewis, D., Linley, C., Maertzdorf, J., Mantovani, A., Mollenkopf, H., Pizzoferro, K., van den Berg, R., Weiner, J.   +16 more
core   +1 more source

Vaccine Potentiation by Combination Adjuvants

Vaccines, 2014
Adjuvants are crucial components of vaccines. They significantly improve vaccine efficacy by modulating, enhancing, or extending the immune response and at the same time reducing the amount of antigen needed. In contrast to previously licensed adjuvants,
Benoît Levast, Sunita Awate, Lorne Babiuk, George Mutwiri, Volker Gerdts, Sylvia van Drunen Littel-van den Hurk   +5 more
doaj   +1 more source

General characteristics of adjuvants and their mechanisms of action (part 2)

Биопрепараты: Профилактика, диагностика, лечение, 2021
One of the major public health challenges today is development of new vaccines and technologies to optimize the vaccination process. There is a growing scientific interest in vaccine adjuvants that enhance vaccine immunogenicity.
N. А. Alpatova, Zh. I. Avdeeva, S. L. Lysikova, O. V. Golovinskaya, L. A. Gayderova, V. P. Bondarev   +5 more
doaj   +1 more source

Distinct immune signatures in directly treated and distant tumors result from TLR adjuvants and focal ablation. [PDF]

, 2018
Both adjuvants and focal ablation can alter the local innate immune system and trigger a highly effective systemic response. Our goal is to determine the impact of these treatments on directly treated and distant disease and the mechanisms for the ...
Borowsky, Alexander D, Chavez, Michael, Davis, Ryan R, Ferrara, Katherine W, Fite, Brett Z, Hubbard, Neil E, Ilovitsh, Asaf, Ingham, Elizabeth S, Mahakian, Lisa M, Monjazeb, Arta M, Murphy, William J, Silvestrini, Matthew T, Tam, Sarah M, Tepper, Clifford G   +13 more
core   +1 more source

Synergistic nano-vaccine strategy for comprehensive activation of adaptive and innate immunity against Staphylococcus aureus infection

Frontiers in Immunology
For decades, Staphylococcus aureus (S. aureus) vaccine development prioritized humoral immunity, heavily relying on recombinant protein antigens adjuvanted with aluminum (Alum), particularly in multivalent formulations.
Jiayue Xi, Jiayue Xi, Minxuan Cui, Minxuan Cui, Zhuoyue Shi, Zhuoyue Shi, Zhuo Wan, Yufei Hou, Yufei Hou, Nan Sun, Nan Sun, Muqiong Li, Muqiong Li, Zhengjun Ma, Zhengjun Ma, Yupu Zhu, Yupu Zhu, Xin He, Xin He, Qian Yang, Zhuojun Shi, Huifang Nie, Huifang Nie, Chaojun Song, Li Fan, Li Fan   +25 more
doaj   +1 more source

Comparative Immunogenicity Evaluation of Characterized Chitosan-Based and Other Adjuvants for Inactivated Influenza Vaccines

Эпидемиология и вакцинопрофилактика, 2016
Chitosan-based adjuvants combine effectiveness, safety and economic feasibility and thus are quite promising for enhancement of influenza control via vaccination, however, problems of characterization and reproducibility remain unresolved; data on ...
L. M. Khantimirova, O. S. Kashirina, M. I. Chernikova, Y. M. Vasiliev   +3 more
doaj   +1 more source