Results 191 to 200 of about 26,392 (248)

Genetic underpinnings of type-2 diabetes (T2D) with colorectal cancer (CRC): In-silico discovery of common molecular signatures, pathogenetic processes and therapeutic candidates. [PDF]

J Genet Eng Biotechnol
Ahmmed R, Antu US, Noor T, Faysal MF, Sarker A, Mahmud S, Ajadee A, Haque Mollah MN.   +7 more
europepmc   +1 more source

<i>In vitro</i> and <i>in vivo</i> studies of dehydroxylated-isoquines and -isotebuquines against trypanosomatids: a preclinical drug candidate for treatment of cutaneous leishmaniasis. [PDF]

RSC Med Chem
Romero AH, Serna E, Aguilera E, Davila B, Delgado F, Scalese G, Pérez-Díaz L, Yaluff G, Rodríguez N, Cerecetto H.   +9 more
europepmc   +1 more source

Advancing PROTAC Discovery Through Artificial Intelligence: Opportunities, Challenges, and Future Directions. [PDF]

Pharmaceuticals (Basel)
Park KS, Jeon M.
europepmc   +1 more source

Selection of Solubility Enhancement Technologies for S-892216, a Novel COVID-19 Drug Candidate. [PDF]

Pharmaceutics
Ohashi R, Otake S, Murata T, Watari R, Yoshida S, Kitade M, Kondo D, Kimura G.   +7 more
europepmc   +1 more source

ADME/T analysis of highest binding compounds towards the target receptors.

Mohammad Abdullah Taher (18691717), Md. Ashraful Islam (8985728), Salsabil Fatima Tasmi (22238207), Mohammad Mahmudul Hasan (18691720), Hasin Hasnat (22238210), Suriya Akter Shompa (22238213), Md Rifaet Hossain (22238216), Mirola Afroze (17706167), Most. Sabila Nazowa (22238219), Mala Khan (13456878)   +9 more
openalex   +1 more source

ADME-drug-likeness: enriching molecular foundation models via pharmacokinetics-guided multi-task learning for drug-likeness prediction. [PDF]

Bioinformatics
Bang D, Kim J, Song H, Kim S.
europepmc   +1 more source

Synthesis and biological evaluation of Trifluoromethoxyphenyl Indole Carboxamide analogs, ADME and toxicity prediction

Baban Mohan Mulik, Noopur Srivastava, Dhananjay S. Pendharkar   +2 more
openalex   +2 more sources

Microphysiological systems as an emerging in vitro approach for the evaluation of drug absorption, distribution, metabolism, and excretion and toxicity. [PDF]

Drug Metab Dispos
Shrimali S, Li D, Knox B, Tong W, Ning B.   +4 more
europepmc   +1 more source

First multifaceted ADME profile of ACP-105 (CAS: 1048998-11-3): a novel non-steroidal selective androgen receptor modulator used as doping in sports-integrative in silico toxicological studies for clinical and forensic toxicology purposes. [PDF]

Arch Toxicol
Fijałkowska O, Jurowski K.
europepmc   +1 more source

Exploring potential phytocompounds from black cumin as drug molecules against SARS-CoV-2 infections through bioinformatics analysis. [PDF]

PLoS One
Ali MA, Sheikh H, Reza MS, Paul TR, Noor T, Kumar N, Bhat MA, Mollah MNH.   +7 more
europepmc   +1 more source