Results 31 to 40 of about 2,370,277 (238)
FEBS Open Bio, EarlyView.Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani +7 more
wiley +1 more source
Clinical observation of COVID-19 treated with fibronectin(FN) inhalation [PDF]
Jichu yixue yu linchuang, 2021 Objective To observe the clinical effect of COVID-19 treated with fibronectin inhalation. Methods Forty-eight COVID-19 patients in Department of Neurology, Xiehe Hospital,Tongji Medical College,Wuhan Huazhong University of Science and Technology,were
LIU Xu-zhi, WU Li-gang, ZHANG Shi-yang, ZHAO Wei-ming, WANG Bin, WANG Hao-qing
doaj
ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells
FEBS Open Bio, EarlyView.Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori +8 more
wiley +1 more source
BMC Pediatrics, 2007 Background Delivery of tobramycin by inhalation to the lungs of patients with cystic fibrosis (CF) who are infected with Pseudomonas aeruginosa has been proven to be effective and safe.
Anbar Ran D, Awa Emad, Santos Roberto P
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective People with epilepsy (PWE) may experience cognitive deficits but fail to undergo formal evaluation. This study compares cognitive status between PWE and healthy controls in the West African Republic of Guinea. Methods A cross‐sectional, case–control study was conducted in sequential recruitment phases (July 2024–July 2025) at Ignace ...
Maya L. Mastick +14 more
wiley +1 more source
Pharmacokinetic study of thymol after intravenous injection and high‐dose inhalation in mouse model
Pharmacology Research & Perspectives, 2019 Thymol is generally recognized as a safe substance by the FDA and has been widely used in the pharmaceutical, food, and cosmetic industries. Pharmacokinetic (PK) studies of thymol have been previously conducted for oral administration, but there has been
Kevin Xie +3 more
doaj +1 more source
Advanced Functional Materials, EarlyView.Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley +12 more
wiley +1 more source
Pediatrics and Neonatology, 2016 Acute bronchiolitis is one of the main respiratory emergencies in young children. Although supportive therapy is recommended, substantial inconsistency in the clinical usage of inhaled treatments has been reported.
Jamie M. Pinto +2 more
doaj +1 more source
Advanced Functional Materials, EarlyView.This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer +7 more
wiley +1 more source
Cogitare Enfermagem, 2019 Objective: to identify which Pressurized Metered-Dose Inhaler with spacer inhalation techniques have been used in patients with asthma. Method: this was an integrative review, conducted in January 2018, in the US National Library of Medicine and Latin ...
Isabela Cristine Ferreira Fernandes +4 more
doaj +1 more source