Pharmaceutics, 2023 Intranasal administration is a promising strategy to enhance the delivery of the sEVsomes-based drug delivery system to the central nervous system (CNS).
Weiwei Shen +5 more
doaj +1 more source
Oxytocin and social pretreatment have similar effects on processing of negative emotional faces in healthy adult males [PDF]
, 2013 Oxytocin has been shown to affect several aspects of human social cognition, including facial emotion processing. There is also evidence that social stimuli (such as eye-contact) can effectively modulate endogenous oxytocin levels.
Hernádi, Anna +3 more
core +1 more source
Cochleates derived from Vibrio cholerae O1 proteoliposomes : The impact of structure transformation on mucosal immunisation [PDF]
, 2012 Cochleates are phospholipid-calcium precipitates derived from the interaction of anionic lipid vesicles with divalent cations. Proteoliposomes from bacteria may also be used as a source of negatively charged components, to induce calcium-cochleate ...
Adriana Callicó +10 more
core +11 more sources
Effects of Topical Intranasal Doxycycline Treatment in the Rat Allergic Rhinitis Model [PDF]
Clinical and Experimental Otorhinolaryngology, 2014 ObjectivesAllergic rhinitis (AR) is a chronic upper respiratory tract disease that inflames the mucous membranes of the nose and occurs when circulating inflammatory cells including eosinophils and basophils migrate to and accumulate in the inflammation ...
Mehmet Ozgür Avincsal +4 more
doaj +1 more source
Mucosal delivery of tuberculosis vaccines: a review of current approaches and challenges. [PDF]
, 2019 Introduction: Tuberculosis (TB) remains a major health threat and it is now clear that the current vaccine, BCG, is unable to arrest the global TB epidemic. A new vaccine is needed to either replace or boost BCG so that a better level of protection could
Barclay WR +8 more
core +1 more source
Drug delivery in overcoming the blood-brain barrier: role of nasal mucosal grafting [PDF]
, 2017 The blood–brain barrier (BBB) plays a fundamental role in protecting and maintaining the homeostasis of the brain. For this reason, drug delivery to the brain is much more difficult than that to other compartments of the body. In order to bypass or cross
Carafa, Maria +5 more
core +1 more source
Журнал микробиологии, эпидемиологии и иммунобиологии, 2019 The aim of present research is studying of protective potency of candidate recombinant live pertussis vaccine (RLPV) for intranasal administration.Materials and methods.
L. N. Sinyashina +4 more
doaj +1 more source
Efficacy of intranasal administration of artesunate in experimental cerebral malaria [PDF]
, 2014 BACKGROUND: Improving management of patients suffering from cerebral malaria is needed to reduce the devastating mortality and morbidity of the disease in endemic areas.
Adeline Lavoignat +7 more
core +2 more sources
Intranasal drug delivery in pediatric emergency departments: brief review and future outlook [PDF]
Pediatric Emergency Medicine Journal, 2023 This review aims to provide an overview and update of current literature on the use of intranasal (IN) drug delivery in pediatric emergency medicine (PEM), in terms of the anatomy, physiology, pharmacokinetics, limitations, drug delivery methods ...
Christopher Hugh McClean +4 more
doaj +1 more source
A new subunit vaccine based on nucleoprotein nanoparticles confers partial clinical and virological protection in calves against bovine respiratory syncytial virus [PDF]
, 2010 Human and bovine respiratory syncytial viruses (HRSV and BRSV) are two closely related, worldwide prevalent viruses that are the leading cause of severe airway disease in children and calves, respectively.
Bernadet, Philippe +14 more
core +2 more sources