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Peripheral T-cell lymphoma (PTCL) is a type of highly heterogeneous non-Hodgkin lymphoma with a poor prognosis and lack of effective targeted therapies. Adoptive T-cell therapy has been successfully used in the treatment of B-cell malignancies.
Yuan Chen +6 more
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Adoptive Natural Killer Cell Immunotherapy for Canine Osteosarcoma
Osteosarcoma is the most common primary bone tumor in both humans and dogs. It is a highly metastatic cancer and therapy has not improved significantly since the inclusion of adjuvant chemotherapy into disease treatment strategies.
William C. Kisseberth, Dean A. Lee
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Adoptive NK Cell Therapy: A Promising Treatment Prospect for Metastatic Melanoma
Adoptive cell therapy (ACT) represents a promising alternative approach for patients with treatment-resistant metastatic melanoma. Lately, tumor infiltrating lymphocyte (TIL) therapy and chimeric antigen receptor (CAR)-T cell therapy have shown improved ...
Monica Raimo +4 more
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Nanoparticles for Enhanced Adoptive T Cell Therapies and Future Perspectives for CNS Tumors
Adoptive T cell therapy has emerged as a revolutionary immunotherapy for treating cancer. Despite immense promise and clinical success in some hematologic malignancies, limitations remain that thwart its efficacy in solid tumors.
Preethi Bala Balakrishnan +1 more
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Introduction: Lung cancer is the second most common cancer worldwide and the leading cause of cancer deaths; non-small cell lung cancer (NSCLC) constitutes about 85% of lung cancer cases, with ALK fusions representing 3–6% of them.
Brenda Paola Rodriguez Arroyo +5 more
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Recurrent neoepitopes are cancer-specific antigens common among groups of patients and therefore ideal targets for adoptive T cell therapy. The neoepitope FSGEYIPTV carries the Rac1P29S amino acid change caused by a c.85C>T missense mutation, which is
Lena Immisch +15 more
doaj +1 more source
Building on the principals that the adoptive transfer of T cells can lead to the regression of established tumors in humans, investigators are now further manipulating these cells using genetic engineering. Two decades of human gene transfer experiments have resulted in the translation of laboratory technology into robust clinical applications.
Richard A, Morgan +2 more
openaire +2 more sources
Related Article from Adoptive T-Cell Therapy for Cancer: Boutique Therapy or Treatment Modality?
Related Article from Adoptive T-Cell Therapy for Cancer: Boutique Therapy or Treatment ...
Cassian Yee (180891)
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ABSTRACT Purpose To explore caregivers' experiences and perceptions of the nutritional challenges faced by children and adolescents undergoing cancer treatment, including oral intake and the use of nutritional support. Methods This was a qualitative study based on focus groups with parents and caregivers at a Brazilian pediatric oncology hospital ...
Danyelle Apparecida Balsamão Marques +5 more
wiley +1 more source
Tumor-infiltrating lymphocytes for adoptive cell therapy
Disclosed are compositions and methods for ex vivo expansion of tumor-infiltrating lymphocytes for use in adoptive cell therapy (ACT). Also disclosed are compositions and method for identifying an agent for ex vivo expansion of tumor-infiltrating ...
Liu, Hao +3 more
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