Results 31 to 40 of about 7,389,456 (292)

A phase I dose-escalation study of neoantigen-activated haploidentical T cell therapy for the treatment of relapsed or refractory peripheral T-cell lymphoma

open access: yesFrontiers in Oncology, 2022
Peripheral T-cell lymphoma (PTCL) is a type of highly heterogeneous non-Hodgkin lymphoma with a poor prognosis and lack of effective targeted therapies. Adoptive T-cell therapy has been successfully used in the treatment of B-cell malignancies.
Yuan Chen   +6 more
doaj   +1 more source

Adoptive Natural Killer Cell Immunotherapy for Canine Osteosarcoma

open access: yesFrontiers in Veterinary Science, 2021
Osteosarcoma is the most common primary bone tumor in both humans and dogs. It is a highly metastatic cancer and therapy has not improved significantly since the inclusion of adjuvant chemotherapy into disease treatment strategies.
William C. Kisseberth, Dean A. Lee
doaj   +1 more source

Adoptive NK Cell Therapy: A Promising Treatment Prospect for Metastatic Melanoma

open access: yes, 2021
Adoptive cell therapy (ACT) represents a promising alternative approach for patients with treatment-resistant metastatic melanoma. Lately, tumor infiltrating lymphocyte (TIL) therapy and chimeric antigen receptor (CAR)-T cell therapy have shown improved ...
Monica Raimo   +4 more
core   +1 more source

Nanoparticles for Enhanced Adoptive T Cell Therapies and Future Perspectives for CNS Tumors

open access: yesFrontiers in Immunology, 2021
Adoptive T cell therapy has emerged as a revolutionary immunotherapy for treating cancer. Despite immense promise and clinical success in some hematologic malignancies, limitations remain that thwart its efficacy in solid tumors.
Preethi Bala Balakrishnan   +1 more
doaj   +1 more source

Partial response to treatment with ALK inhibitor in a patient with SQSTM1-ALK fusion positive lung adenocarcinoma

open access: yesEuropean Journal of Case Reports in Internal Medicine
Introduction: Lung cancer is the second most common cancer worldwide and the leading cause of cancer deaths; non-small cell lung cancer (NSCLC) constitutes about 85% of lung cancer cases, with ALK fusions representing 3–6% of them.
Brenda Paola Rodriguez Arroyo   +5 more
doaj   +1 more source

Targeting the recurrent Rac1P29S neoepitope in melanoma with heterologous high-affinity T cell receptors

open access: yesFrontiers in Immunology, 2023
Recurrent neoepitopes are cancer-specific antigens common among groups of patients and therefore ideal targets for adoptive T cell therapy. The neoepitope FSGEYIPTV carries the Rac1P29S amino acid change caused by a c.85C>T missense mutation, which is
Lena Immisch   +15 more
doaj   +1 more source

Adoptive Cell Therapy [PDF]

open access: yesThe Cancer Journal, 2010
Building on the principals that the adoptive transfer of T cells can lead to the regression of established tumors in humans, investigators are now further manipulating these cells using genetic engineering. Two decades of human gene transfer experiments have resulted in the translation of laboratory technology into robust clinical applications.
Richard A, Morgan   +2 more
openaire   +2 more sources

Related Article from Adoptive T-Cell Therapy for Cancer: Boutique Therapy or Treatment Modality?

open access: yes, 2013
Related Article from Adoptive T-Cell Therapy for Cancer: Boutique Therapy or Treatment ...
Cassian Yee (180891)
core   +1 more source

Feeding, Fear, and Acceptance: Caregivers’ Experiences of Nutritional Support During Childhood Cancer Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose To explore caregivers' experiences and perceptions of the nutritional challenges faced by children and adolescents undergoing cancer treatment, including oral intake and the use of nutritional support. Methods This was a qualitative study based on focus groups with parents and caregivers at a Brazilian pediatric oncology hospital ...
Danyelle Apparecida Balsamão Marques   +5 more
wiley   +1 more source

Tumor-infiltrating lymphocytes for adoptive cell therapy

open access: yes, 2022
Disclosed are compositions and methods for ex vivo expansion of tumor-infiltrating lymphocytes for use in adoptive cell therapy (ACT). Also disclosed are compositions and method for identifying an agent for ex vivo expansion of tumor-infiltrating ...
Liu, Hao   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy