Results 61 to 70 of about 65,713 (156)
Chimeric Antigen Receptor T Cell Therapy in Hematology
Turkish Journal of Hematology, 2015 It is well demonstrated that the immune system can control and eliminate cancer cells. Immune-mediated elimination of tumor cells has been discovered and is the basis of both cancer vaccines and cellular therapies including hematopoietic stem cell ...
Pınar Ataca, Önder Arslan
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Thermal sonogenetics for adoptive cell transfer therapy
Journal of Controlled ReleaseAdoptive cell transfer (ACT)-based immunotherapy has emerged as a transformative approach for treating cancer, offering durable responses through the ex vivo expansion and reinfusion of antigen-specific immune cells. Despite remarkable clinical successes, most notably with chimeric antigen receptor (CAR)-T cell therapy, ACT remains limited by severe ...
Ana, Baez +6 more
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Adoptive transfer of natural killer cells in therapeutic treatment of COVID-19 patients
Egyptian Journal of Medical Human GeneticsBackground Natural killer (NK) cells are crucial constituents of innate immunity, playing a vital role in the early defense against viral infections and cancer.
Abdulaziz Alamri
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NIH3T3 Directs Memory-Fated CTL Programming and Represses High Expression of PD-1 on Antitumor CTLs
Frontiers in Immunology, 2019 Memory CD8+ T cells have long been considered a promising population for adoptive cell therapy (ACT) due to their long-term persistence and robust re-stimulatory response. NIH3T3 is an immortalized mouse embryonic fibroblast cell line.
Yingyu Qin +5 more
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Frontiers in Immunology, 2019 CAR-NK cells may represent a valuable tool, complementary to CAR-T cells, in adoptive immunotherapy of leukemia and solid tumors. However, gene transfer to human NK cells is a challenging task, particularly with non-virus-based techniques.
Tiziano Ingegnere +11 more
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Transport of Adoptive Cell Transfers With Magnetic Helical Microrobots
SmallAbstract Adoptive cell transfers (ACTs) can interact specifically with inflamed tissues, but lack a mechanism for transport through viscous biological barriers such as mucus when administered locally. Further, maintaining cell function is challenging due to the loss of cellular phenotypes in diseased microenvironments.
Ritu R. Raj +5 more
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Adoptive Transfer of Allogeneic Antigen-Specific T Cells
Biology of Blood and Marrow Transplantation, 2006 Animal models and human studies of allogeneic hematopoietic cell transplantation (HCT) demonstrate that immunologic nonidentity between donor and recipient is responsible for a graft versus leukemia (GVL) effect that contributes to complete tumor eradication.
Riddell, Stanley R. +4 more
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Adoptive cell transfer of macrophages following peripheral nerve injury in mice. [PDF]
STAR Protoc, 2023 Rawat A, Jha MK, Morrison BM.
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Toxicities Associated With Adoptive T-Cell Transfer for Cancer [PDF]
The Cancer Journal, 2015 This review describes the toxicities associated with the therapeutic administration of cultured immune cells for the treatment of cancer by review of the literature. The toxicities seen are of 4 types: infection associated with preparative host immunosuppression with chemotherapy prior to cell administration, acute cytokine release by the infused cells,
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Frontiers in Immunology, 2019 The successful generation of T cell-mediated immunity for the treatment of cancer has been a major focal point of research. One of the critical strategies of cancer immunotherapy is to efficiently activate antigen-specific CD8 T cells in the ...
Jin-Zhi Lai +5 more
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