Compared with EBV‐negative epithelial cancer cells, EBV‐associated epithelial cancer cells exhibit enhanced secretion of chemokines, including CXCL10 and CCL5, to attract neutrophils. Via the CXCL10‐CXCR3 axis‐mediated positive feedback loop, neutrophils within EBV‐associated epithelial cancer cells are induced to form abundant NETs, which facilitate ...
Dijun Ouyang+24 more
wiley +1 more source
Adoptive immunotherapy: Engineering T cell responses as biologic weapons for tumor mass destruction [PDF]
William Ho+4 more
openalex +1 more source
Nanoparticle-based modulation of CD4+ T cell effector and helper functions enhances adoptive immunotherapy. [PDF]
Isser A+17 more
europepmc +1 more source
Adoptive cell transfer as personalized immunotherapy for human cancer
S. Rosenberg, N. Restifo
semanticscholar +1 more source
Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang+4 more
wiley +1 more source
Divergent Roles for CD4+ T Cells in the Priming and Effector/Memory Phases of Adoptive Immunotherapy
Hong‐Ming Hu+3 more
openalex +1 more source
Ablation of T cell-associated PD-1H enhances functionality and promotes adoptive immunotherapy. [PDF]
Hu L+9 more
europepmc +1 more source
Chen et al. identified a metabolic gene prognostic signature with machine‐learning framework and assessed the prognostic value in independent CRC cohorts. The metabolic signature subtypes are characterized by specific metabolic and proteomic characteristics, and associated with distinct molecular pathway and therapeutic potential.
Hao Chen+12 more
wiley +1 more source
Newest Approaches in Immunotherapy for Non-Hodgkin’s Lymphoma
Immunotherapy has revolutionised the treatment of haematologic malignancies. Patients with relapsed/refractory non-Hodgkin’s lymphoma have poor response rates and short survival times when conventional cytotoxic chemotherapies are used.
Emily C. Ayers, Sunita D. Nasta
doaj
A Pancreatic Cancer Patient-Derived Xenograft Model for Adoptive Immunotherapy Using Autologous Tumor-Infiltrating Lymphocytes. [PDF]
Leone V, Peschke K, Reichert M.
europepmc +1 more source