Results 151 to 160 of about 54,884 (249)

Electrostatically‐Stabilized PEG‐Free Lipid Nanoparticles for Systemic Nucleic Acid Delivery

Advanced Functional Materials, EarlyView.
This work describes non‐PEGylated layered lipid nanoparticles (nonPEG LLNPs), a gene delivery platform that improves upon standard PEGylated LNPs via electrostatic adsorption of charged polymers. nonPEG LLNPs maintain colloidal stability under biological stresses, enhance circulation time, and mitigate accelerated blood clearance and hepatic ...
Namita Nabar, Deeksha Kumaresh, Eduardo Nombera Bueno, Mae Pryor, Paula T. Hammond   +4 more
wiley   +1 more source

SCAN-ACT: adoptive T cell therapy target discovery through single-cell transcriptomics. [PDF]

Genome Med
Testa S, Pal A, Subramanian A, Varma S, Tang JP, Graham D, Arfan S, Pan M, Bui NQ, Ganjoo KN, Dry S, Huang P, van de Rijn M, Jiang W, Kalbasi A, Moding EJ.   +15 more
europepmc   +1 more source

Si‐Doped Nanocrystalline Diamond as Highly Sensitive Luminescence Thermometer for the Physiological Temperature Range

Advanced Functional Materials, EarlyView.
In this work, diamonds with negative charged silicon‐vacancy (SiV−) centers have been designed for use as thermometers in biomedical applications. Multiparametric analysis of the emission characteristics of the SiV− centers provides extraordinary sensitivity for temperature detection in the physiological temperature range.
María Gragera, Iván Carrillo‐Berdugo, Josue Millán, Paulius Pobedinskas, Antonio Freire, Ken Haenen, Javier Navas   +6 more
wiley   +1 more source

The current landscape of optogenetics for the enhancement of adoptive T-cell therapy. [PDF]

Discov Immunol
Smith GR, Lee MP, Jennings EK, James JR.
europepmc   +1 more source

Adoptive T cell therapy cures mice from active hemophagocytic lymphohistiocytosis (HLH). [PDF]

EMBO Mol Med, 2022
Weißert K, Ammann S, Kögl T, Dettmer-Monaco V, Schell C, Cathomen T, Ehl S, Aichele P.   +7 more
europepmc   +1 more source

Interaction‐Driven Assembly Pathways in Heterogeneous Active Microrobotic Systems

Advanced Functional Materials, EarlyView.
Peanut‐ and cube‐shaped light‐powered microrobots exhibit distinct magnetic and photocatalytic responses that determine their heterogeneous self‐assembly. In the dark, magnetic dipole interactions drive colloidal copolymerization with cubes acting as nucleation centers, whereas under light irradiation, phoretic interactions compete with magnetic ...
Domenico Calabrò, Roshan Velluvakandy, Martin Pumera, Francesco Priolo, Salvo Mirabella, Mario Urso   +5 more
wiley   +1 more source

A TGF-βR/IL-2R immunomodulatory fusion protein transforms immunosuppression into T cell activation to enhance adoptive T cell therapy. [PDF]

Proc Natl Acad Sci U S A
Su Y, Thelen A, Wirth LV, Jenkins CM, Mak SR, Chen DG, Gottardo R, Greenberg PD.   +7 more
europepmc   +1 more source

Enhancing adoptive T-cell therapy with fucoidan-based IL-2 delivery microcapsules. [PDF]

Bioeng Transl Med, 2023
Jeon EY, Choi DS, Choi S, Won JY, Jo Y, Kim HB, Jung Y, Shin SC, Min H, Choi HW, Lee MS, Park Y, Chung JJ, Jin HS.   +13 more
europepmc   +1 more source

Snap‐Through–Driven Liquid Crystal Elastomers for High‐Power Remote Microneedle Actuation Toward Smart Livestock Systems

Advanced Functional Materials, EarlyView.
A magnetically assisted snap‐through liquid crystal elastomer transforms photochemical deformation into a high‐power mechanical impulse, enabling remote microneedle actuation and highlighting its potential for future smart livestock intervention systems.
Chae Won Lee, Nankyung Kim, SeungHyun Park, Dae Seok Kim   +3 more
wiley   +1 more source

152 Adoptive T cell therapy targeting somatic p53 mutations

Journal for ImmunoTherapy of Cancer, 2020
Nikolaos Zacharakis, Parisa Malekzadeh, Peter Kim, Nolan Vale, Elizabeth Hedges   +4 more
doaj   +1 more source