Results 91 to 100 of about 3,533 (177)

Cytoskeleton-dependent inhibition of the ADP-ribosyl cyclase activity of CD38 in thrombin-stimulated platelets

, 1998
Stimulation of human platelets with thrombin caused a 42% inhibition of the ADP-ribosyl cyclase activity of membrane CD38. This effect was mediated by the activation of the platelet thrombin receptor rather than by proteolysis of CD38, and was not due to
Torti, Mauro, BERTONI A., Cesare Balduini, Balduini C., Mauro Torti, Tolnai Festetics, Enrico, Torti M, Balduini, Cesare, Tolnai Festetics E, Alessandra Bertoni, Enrico Tolnai Festetics, Fabiola Sinigaglia, Bertoni, Alessandra, SINIGAGLIA F., TOLNAI FESTETICS E., Sinigaglia, Fabiola   +15 more
core   +1 more source

GDP-ribosyl cyclase activity as a measure of CD38 induction by retinoic acid in HL-60 cells

, 1994
Retinoic acid (RA) treatment of HL-60 cells induces surface expression of CD38. This lymphocytic antigen is also a novel bifunctional enzyme catalyzing the synthesis and hydrolysis of cyclic ADP-ribose (cADPR), a Ca2+ mobilizing metabolite of NAD+.
Graeff, RM, Mehta, K, Lee, HC
core   +1 more source

Structure, function and regulation of BP-3, a member of the CD38/ADP-ribosyl cyclase family

, 1996
The murine BP-3 gene encodes a variably glycosylated phosphatidylinositollinkcd cell surface glycoprotein that is expressed on early B and T lineage cells, myeloid cells, intestinal epithelial cells and a discrete population of reticular cells in ...
Cooper, MD, Graeff, RM, Willerfbrd, DD, Alt, F, Lee, HC   +4 more
core  

ADP-Ribosyl Cyclase 1 [PDF]

, 2020
openaire   +1 more source

Characterization of ADP-ribosyl cyclase 1-like (ARC1-like) activity and NAADP signaling during slow muscle cell development in zebrafish embryos. [PDF]

Dev Biol, 2019
Kelu JJ, Webb SE, Galione A, Miller AL.
europepmc   +1 more source

Bradykinin activates ADP-ribosyl cyclase in neuroblastoma cells: Intracellular concentration decrease in NAD and increase in cyclic ADP-ribose

ADP-ribosyl cyclase activity in the crude membrane fraction of neuroblastoma × glioma NGPM1-27 hybrid cells was measured by monitoring [3H] cyclic ADP-ribose (cADPR) formation from [3H] NAD+.
Salmina, Alla, Yokoyama, Shigeru, Noda, Mami, Zhang, Jia-Sheng, Zhong, Zen-Guo, Hashii, Minako, Higashida, Haruhiro   +6 more
core  

An investigation of NAADP-dependent Ca²⁺ signalling mechanisms in arterial smooth muscle

, 2007
Previous investigations on pulmonary artery smooth muscle cells have shown that nicotinic acid adenine dinucleotide diphosphate (NAADP) evokes highly localised intracellular Ca²⁺ bursts by mobilising thapsigargin-insensitive Ca²⁺ stores.
Kinnear, Nicholas P.
core  

Intermediates along the NAD+ cyclisation reaction pathway of ADP-ribosyl cyclase

, 2011
Calcium is a ubiquitous, versatile intracellular signal regulating numerous cellular processes [1]. The versatility of Ca2+ signalling emerges from the use of an extensive repertoire of signalling components known as a Ca2+ signalling toolkit that can be
Hao, Q, Zhang, L, Kotaka, M, Graeff, R, Lee, HC   +4 more
core  

Cyclic adenosine 5'-diphosphate ribose analogs without a "southern" ribose inhibit ADP-ribosyl cyclase-hydrolase CD38. [PDF]

J Med Chem, 2014
Swarbrick JM, Graeff R, Zhang H, Thomas MP, Hao Q, Potter BV.   +5 more
europepmc   +1 more source

Pathological Mechanisms in Sjögren's Disease Likely Involve the ADP-Ribosyl Cyclase Family Members: CD38 and CD157. [PDF]

Int J Mol Sci
Rosecka M, Kolackova M, Afshari M, Jozifkova E, Slezak R, Krejsek J, Radochova V.   +6 more
europepmc   +1 more source