ADP-ribosylation from molecular mechanisms to therapeutic implications. [PDF]
, 2023 ADP-ribosylation is a ubiquitous modification of biomolecules, including proteins and nucleic acids, that regulates various cellular functions in all kingdoms of life.
I Ahel (7716542) +3 more
core +6 more sources
Journal of Innate Immunity, 2020 Pulmonary macrophages play a critical role in the recognition of pathogens, initiation of host defense via inflammation, clearance of pathogens from the airways, and resolution of inflammation.
Yunjuan Nie +8 more
doaj +1 more source
Selection of new appropriate reference genes for RT-qPCR analysis via transcriptome sequencing of cynomolgus monkeys (Macaca fascicularis). [PDF]
PLoS ONE, 2013 In the investigation of the expression levels of target genes, reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR) is the most accurate and widely used method.
Sang-Je Park +10 more
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Recruitment of AP-1 clathrin adaptors to liposomal membranes [PDF]
, 2004 Protein and membrane traffic between organelles within the endocytic and exocytic pathway is mediated most prominently by coated vesicles. These vesicles are formed by the assembly of cytosolic coat proteins onto the donor membrane, which deform it into ...
Meyer, Daniel Markus
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Trans-Golgi proteins participate in the control of lipid droplet and chylomicron formation
Bioscience Reports, 2012 LDs (lipid droplets) carrying TAG (triacylglycerol) and cholesteryl esters are emerging as dynamic cellular organelles that are generated in nearly every cell. They play a key role in lipid and membrane homoeostasis.
Deike Hesse +3 more
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ARF-GAP-mediated interaction between the ER-Golgi v-SNAREs and the COPI coat [PDF]
, 2002 In eukaryotic cells, secretion is achieved by vesicular transport. Fusion of such vesicles with the correct target compartment relies on SNARE proteins on both vesicle (v-SNARE) and the target membranes (t-SNARE).
Rein, U. +15 more
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Mechanistic insights into the HPF1/PARP1 complex [PDF]
, 2022 ADP-ribosylation is a vital post-translational modification associated with a large range of processes including DNA damage repair, transcription, replication, mitosis, inflammation and cell death.
Zobel, Florian Franz Henning
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Class I ADP-ribosylation factors are involved in enterovirus 71 replication.
PLoS ONE, 2014 Enterovirus 71 is one of the major causative agents of hand, foot, and mouth disease in infants and children. Replication of enterovirus 71 depends on host cellular factors.
Jianmin Wang, Jiang Du, Qi Jin
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Inactivation of the three GGA genes in HeLa cells partially compromises lysosomal enzyme sorting
FEBS Open Bio, 2021 The Golgi‐localized, gamma‐ear containing, ADP‐ribosylation factor‐binding proteins (GGAs 1, 2, and 3) are multidomain proteins that bind mannose 6‐phosphate receptors (MPRs) at the Golgi and play a role, along with adaptor protein complex 1 (AP‐1), in ...
Balraj Doray +4 more
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A cytosolic factor mediating membrane recruitment of AP-1 clathrin adaptors [PDF]
, 2008 Transport of cargo within the endocytic and secretory pathway is generally mediated by coated vesicles. These vesicles are formed through the recruitment of cytosolic coat proteins to the donor membrane that act as a scaffold to form coated buds and ...
Suri, Gregor
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