Results 21 to 30 of about 32,710,223 (183)

A Study into the ADP-Ribosylome of IFN-γ-Stimulated THP‑1 Human Macrophage-like Cells Identifies ARTD8/PARP14 and ARTD9/PARP9 ADP-Ribosylation

, 2019
ADP-ribosylation is a post-translational modification that, until recently, has remained elusive to study at the cellular level. Previously dependent on radioactive tracers to identify ADP-ribosylation targets, several advances in mass spectrometric ...
Takashi Maejima (559317), Lang Ho Lee (5901176), Sasha A. Singh (5901179), Yukiyoshi Yamazaki (6491339), Masanori Aikawa (529883), Hideyuki Higashi (6491336), Michael O. Hottiger (27949)   +6 more
core   +3 more sources

Study of the role of transmembrane emp24 domain-containing protein 2 in oral squamous cell carcinoma [PDF]

Journal of Applied Oral Science
Objective This study aimed to investigate the role of transmembrane emp24 domain-containing protein 2 (TMED2) in oral squamous cell carcinoma (OSCC). Methodology A bioinformatics analysis was first conducted to explore TMED2 expression in OSCC and its
RUAN Zhao-wei, JIAO Xue-feng, XIAO Gao-tian, CHEN Jin-ling, LI Jun, LV Shu-ying   +5 more
doaj   +1 more source

TARG1 protects against toxic DNA ADP-ribosylation [PDF]

, 2021
ADP-ribosylation is a modification that targets a variety of macromolecules and regulates a diverse array of important cellular processes. ADP-ribosylation is catalysed by ADP-ribosyltransferases and reversed by ADP-ribosylhydrolases.
Sanchi, Andrea, Tromans-Coia, Callum, Timinszky, Gyula, Moeller, Giuliana K., Ahel, Ivan; https://orcid.org/, Lopes, Massimo, Moeller, Giuliana K, Lopes, Massimo; https://orcid.org/   +7 more
core   +1 more source

ARF6 regulates neuron differentiation through glucosylceramide synthase. [PDF]

PLoS ONE, 2013
The small GTPase ADP ribosylation factor 6 (ARF6) mediates endocytosis and has in addition been shown to regulate neuron differentiation. Here we investigated whether ARF6 promotes differentiation of Neuro-2a neuronal cells by modifying the cellular ...
Lu Li, Marcus Ståhlman, Mikael Rutberg, Liliana Håversen, Per Fogelstrand, Linda Andersson, Malin Levin, Jan Borén   +7 more
doaj   +1 more source

The ArfGEF GBF-1 Is Required for ER Structure, Secretion and Endocytic Transport in C. elegans [PDF]

, 2013
Small GTPases of the Sar/Arf family are essential to generate transport containers that mediate communication between organelles of the secretory pathway.
Anne Spang, Ackema, K. B., Jachen A Solinger, Karin B Ackema, Ursula Sauder, Solinger, J. A., Karin B. Ackema, Jachen A. Solinger (254344), Jachen A. Solinger, Karin B. Ackema (423507), Ursula Sauder (250540), Spang, A., Anne Spang (205738), Sauder, U.   +13 more
core   +2 more sources

BIOCHEMICAL AND STRUCTURAL STUDIES OF PATHOGEN EFFECTORS ASSOCIATED WITH UBIQUITIN ADP-RIBOSYLATION

, 2023
Ubiquitination and ADP-ribosylation are reversible post-translational modifications involved in various cellular activities. Pathogens like Legionella pneumophila and Chromobacterium violaceum target host ubiquitin system via modifications involving ADP ...
Zhengrui Zhang (17081689)
core   +1 more source

Identification of reference genes for quantitative expression analysis of microRNAs and mRNAs in barley under various stress conditions. [PDF]

PLoS ONE, 2015
For accurate and reliable gene expression analysis using quantitative real-time reverse transcription PCR (qPCR), the selection of appropriate reference genes as an internal control for normalization is crucial.
Jannatul Ferdous, Yuan Li, Nicolas Reid, Peter Langridge, Bu-Jun Shi, Penny J Tricker   +5 more
doaj   +1 more source

Infectious Bursal Disease Virus Assembly Causes Endoplasmic Reticulum Stress and Lipid Droplet Accumulation

Viruses, 2023
Gumboro illness is caused by the highly contagious immunosuppressive infectious bursal disease virus (IBDV), which affects the poultry industry globally.
Yesica R. Frontini-López, Lautaro Rivera, Cristian A. Pocognoni, Julieta S. Roldán, María I. Colombo, Marina Uhart, Laura R. Delgui   +6 more
doaj   +1 more source

A Protein Semisynthesis-Based Strategy to Investigate the Functional Impact of Linker Histone Serine ADP-Ribosylation

, 2022
Recently developed chemical and enzyme-based technologies to install serine ADP-ribosylation onto synthetic peptides have enabled new approaches to study poly­(ADP-ribose) polymerase (PARP) biology.
Chad A. Brautigam (242609), Jugal Mohapatra, Kyuto Tashiro (6518141), Glen Liszczak (109196), Kyuto Tashiro, Jugal Mohapatra (12270396), Glen Liszczak, Chad A. Brautigam   +7 more
core   +1 more source

In-frame cDNA library combined with protein complementation assay identifies ARL11-binding partners. [PDF]

PLoS ONE, 2012
The cDNA expression libraries that produce correct proteins are essential in facilitating the identification of protein-protein interactions. The 5'-untranslated regions (UTRs) that are present in the majority of mammalian and non-mammalian genes are ...
Sangkyou Lee, Ilkyun Lee, Yoonsuh Jung, David McConkey, Bogdan Czerniak   +4 more
doaj   +1 more source