Results 111 to 120 of about 3,569 (120)

The Effect of Benzamides on the Activity of Nuclear ADP-Ribosyl Transferase and the Accumulation of Poly(ADP-Ribose) In Vivo

1989
Investigation of the cellular role of the nuclear protein modification ADP-ribosylation has depended heavily on the use of benzamides as inhibitors of ADP-ribosyl transferase (EC 2.4.2.30) in intact cell studies. The substituted benzamides were first introduced by Whish (1) and have proved to be useful inhibitors of low toxicity and fairly high ...
Christopher J. Skidmore, Janet Jones, Bhartiben N. Patel   +2 more
openaire   +1 more source

Inhibitor of poly(ADP-ribose)transferase potentiates the recombinogenic but not the mutagenic action of alkylating agents in somatic cells in vivo in Drosophila melanogaster

Mutagenesis, 1990
The effect on somatic mutations and recombination by 3-aminobenzamide (3-ABA), an inhibitor of poly(ADP-ribose) transferase, was studied in the somatic wing spot test in Drosophila melanogaster, 3-ABA did not exert any effect by itself, but caused a strong increase of wing spots in combination with methyl methanesulphonate (MMS) and ethylnitrosourea ...
J, Magnusson, C, Ramel
openaire   +2 more sources

[(ADP-ribose)n-transferase activity of enterocyte nuclei during radiation injury of small intestine mucosa in rats].

Ukrainskii biokhimicheskii zhurnal (1978), 1986
The (ADP-ribose)n transferase activity of enterocyte nuclei of small intestine is studied in rats in normal and under radiation injury of intestine mucosa. It is shown that kinetics of [14C]-NAD incorporation into the acid-insoluble fraction of enterocyte nuclei is of a two-step character when the medium contains 1-15 microM of NAD.
T B, Trofimiak, Ia B, Blium, B F, Sukhomlinov, N E, Kucherenko   +3 more
openaire   +1 more source

The effect of inhibitors of ADP-ribose transferase on the concentration of (ADP-ribose)n in vivo

Biochemical Society Transactions, 1984
WILLIAM H. MULLEN, LINDSAY MINSHALL, WILLIAM J. D. WHISH   +2 more
openaire   +1 more source

Analogues of benzamide as poly(ADP-ribose)transferase inhibitors: A study on structure activity relationships

Pharmacological Research Communications, 1988
SESTILI, PIERO, BALSAMINI, CESARINO, SPADONI, GILBERTO, CATTABENI F, CANTONI, ORAZIO   +4 more
openaire   +3 more sources

Effect of phorbol esters on ADP-ribose transferase in cultured mouse lymphoma (L1210) cells

Biochemical Society Transactions, 1984
MARK WRIGHTMAN, DIANE FURNISS, WILLIAM J. D. WHISH   +2 more
openaire   +1 more source

Substituted benzamides as poly(adp-ribose) transferase inhibitors: development of new derivatives by using computer graphics techniques

Pharmacological Research, 1989
SESTILI, PIERO, BALSAMINI, CESARINO, SPADONI, GILBERTO, E. DURANTI, F. CATTABENI, D. HIGGINS, C. THOMSON, CANTONI, ORAZIO   +7 more
openaire   +3 more sources

Inhibition of stress-activated protein kinase in the ischemic/reperfused heart: role of magnesium tanshinoate B in preventing apoptosis11Abbreviations: JIP, JNK-interacting protein; MAP, mitogen-activated protein; p38 MAPK, p38 MAP kinase; MTB, magnesium tanshinoate B; PARP, poly(ADP-ribose) polymerase; PMSF, phenylmethylsulfonyl fluoride; SAP, stress-activated protein; and TUNEL, terminal deoxyribonucleotide transferase (TdT)-mediated dUTP nick-end labeling.

Biochemical Pharmacology, 2001
Kathy K.W. Au-Yeung, Da-yuan Zhu, Karmin O, Yaw L. Siow   +3 more
openaire   +1 more source

Recombination and mutations induced in somatic cells of Drosophila melanogaster by alkylating agents after modulation of poly-ADP-ribose transferase and topoisomerase

Mutation Research/Environmental Mutagenesis and Related Subjects, 1992
openaire   +1 more source

A mechanism underlying susceptibility to HBV infection: HBV down-regulate transferase-1 type I interferon receptor 1 via suppressing poly(ADP-ribose)

2010
Ng, F, Guan, XY, Chan, CS, Yuen, KY, Zheng, B, Watt, RM, Huang, J, Zhou, J, Chen, D, Poon, KM, Lu, L   +10 more
openaire   +1 more source