Results 21 to 30 of about 130,603 (363)
Dichlorodiphenyltrichloroethane and the Adrenal Gland: From Toxicity to Endocrine Disruption
Endocrine disruptors are exogenous compounds that pollute the environment and have effects similar to hormones when inside the body. One of the most widespread endocrine disruptors in the wild is the pesticide dichlorodiphenyltrichloroethane (DDT). Toxic
Ekaterina P. Timokhina+2 more
doaj +1 more source
Abstract Objective Childhood cancer and cancer‐related treatments disrupt brain development and maturation, placing survivors at risk for cognitive late effects. Given that assessment tools vary widely across researchers and clinicians, it has been daunting to identify distinct patterns in outcomes across diverse cancer types and to implement ...
Julie A. Trapani, Donna L. Murdaugh
wiley +1 more source
Age-related Changes in the Adrenal Cortex: Insights and Implications
Aging is characterized by a gradual decline in physiological function. This process affects all organs including the adrenal cortex, which normally functions to produce essential steroid hormones including mineralocorticoids, glucocorticoids, and ...
Kate M Warde+2 more
semanticscholar +1 more source
The main objective of this work was to obtain detailed information on the distribution and localization of the spexin (Spx) system in the sea bass brain. To this purpose, we first identified and characterized the spx1 gene and analyzed its expression in the central nervous system (CNS) of the European sea bass by using quantitative Real‐Time Polymerase
José A. Paullada‐Salmerón+2 more
wiley +1 more source
The Sexually Dimorphic Adrenal Cortex: Implications for Adrenal Disease
Many adrenocortical diseases are more prevalent in women than in men, but the reasons underlying this sex bias are still unknown. Recent studies involving gonadectomy and sex hormone replacement experiments in mice have shed some light onto the molecular
Rodanthi Lyraki, A. Schedl
semanticscholar +1 more source
Chronic adrenal insufficiency is caused by insufficient secretion of hormones by the adrenal cortex due to dysfunction of one or more links of the hypothalamic-pituitary-adrenal system.
V. G. Chobitko, A. P. Belova
doaj +1 more source
Challenging Diagnosis of Addison’s Disease Presenting with Adrenal Crisis
Primary adrenal insufficiency, also known as Addison’s disease, is a rare but potentially fatal condition resulting from the failure of the adrenal cortex to produce glucocorticoid and/or mineralocorticoid hormones.
Ni Wayan Wina Dharmesti+4 more
doaj +1 more source
A spatiotemporal steroidogenic regulatory network in human fetal adrenal glands and gonads
Human fetal adrenal glands produce substantial amounts of dehydroepiandrosterone (DHEA), which is one of the most important precursors of sex hormones. However, the underlying biological mechanism remains largely unknown. Herein, we sequenced human fetal
Yifu Wang+93 more
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Background Glycogen storage disease type I (GSDI) is an inborn error of carbohydrate metabolism caused by mutations of either the G6PC gene (GSDIa) or the SLC37A4 gene (GSDIb).
Alessandro Rossi+9 more
doaj +1 more source
Effect of different types of stress on adrenal gland parameters and adrenal hormones in the blood serum of male Wistar rats [PDF]
In the present study, we examined gross changes in the mass of whole adrenal glands and that of the adrenal cortex and medulla in mature male Wistar rats subjected to three different stress types: acute, chronic, and combined, i.e., chronic followed by ...
Adžić M.+4 more
doaj +1 more source