Results 91 to 100 of about 42,588 (295)

Vesicular glutamate transporter VGLUT2 expression emerges in substantia nigra dopamine neurons in mouse models of parkinsonism in the absence of neurodegeneration

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Subsets of midbrain dopamine (DA) neurons express the vesicular glutamate transporter VGLUT2 and can release the excitatory neurotransmitter glutamate. VGLUT2+ DA neurons of the substantia nigra pars compacta (SNc) were shown to be more resistant to neurodegeneration in animal models of Parkinson's disease (PD ...
Sivakumar Srinivasan, Christian Pifl, Thomas Steinkellner   +2 more
wiley   +1 more source

A novel octopamine receptor with preferential expression in Drosophila mushroom bodies [PDF]

, 1998
Octopamine is a neuromodulator that mediates diverse physiological processes in invertebrates. In some insects, such as honeybees and fruit flies, octopamine has been shown to be a major stimulator of adenylyl cyclase and to function in associative ...
Han, K-A, Millar, NS
core  

A role for epithelium‐derived 6‐nitrodopamine on human ureter contractility

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose To investigate the basal release of 6‐nitrodopamine (6‐ND) from human isolated ureter and the role of this novel catecholamine in the ureter contractility. Experimental Approach Ureters from 67 brain‐dead organ donors (40 males and 27 females) were used during kidney transplantation procedures.
Wilmar Azal Neto, Denis Lima Oliveira, José Britto‐Júnior, Alex Henrique Miller, Flaviano Lorenzon, Felipe Fernandes Jacintho, Valéria Barbosa de Souza, Fernanda Viviane Mariano, André Almeida Schenka, Fabiola Zakia Mónica, Adriano Fregonesi, Edson Antunes, Gilberto De Nucci   +12 more
wiley   +1 more source

Opioids in breast cancer: Between analgesia and modulation of tumour progression

British Journal of Pharmacology, EarlyView.
Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun, Anna Tankiewicz‐Kwedlo, Dariusz Pawlak   +2 more
wiley   +1 more source

Role of Selective α and β Adrenergic Receptor Mechanisms in Rat Jejunal Longitudinal Muscle Contractility [PDF]

, 2018
Gut motility is modulated by adrenergic mechanisms. The aim of our study was to examine mechanisms of selective adrenergic receptors in rat jejunum. Spontaneous contractile activity of longitudinal muscle strips from rat jejunum was measured in 5-ml ...
Balsiger, Bruno, Haefliger, Simon, Rickenbacher, Andreas, Seiler, Roland, Shaw, Sidney   +4 more
core  

Cardiovascular Health in Women—Across the Lifespan

Clinical Endocrinology, EarlyView.
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar, Jessica Yao, Simone Gong, Madhuka Wijayarathne, Monique Watts, Swati Mukherjee   +5 more
wiley   +1 more source

Current and prospective pharmacological targets in relation to antimigraine action [PDF]

, 2008
Migraine is a recurrent incapacitating neurovascular disorder characterized by unilateral and throbbing headaches associated with photophobia, phonophobia, nausea, and vomiting. Current specific drugs used in the acute treatment of migraine interact with
A Bergerot, A Buchwalder, A Carlsson, A Carlsson, A Hughes, A MaassenVanDenBrink, A MaassenVanDenBrink, A May, A May, A May, A Pindon, A Rouleau, A Srikiatkhachorn, A Sudilovsky, A Tanoue, A Wackenfors, AC Honey, AD Bennett, AD Medhurst, AD Michel, AE Luebke, AH Bom, AH Calhoun, AJ Kaumann, AL Magos, AM Aloisi, AM Carruthers, AM Lands, AM Maagdenberg van den, Antoinette MaassenVanDenBrink, AP Ford, AP Silva, B Forssman, B Gómez-Mancilla, B Pouzet, B Schaerlinger, B Weiss, BB Fredholm, BB Hoffman, BJ Francken, BK Kobilka, BK Rasmussen, BW Somerville, BW Somerville, C Hofmann, C Hohoff, C Lampl, C Tzourio, CA Salvatore, Carlos M. Villalón, CG Dahlöf, CM Villalón, CM Villalón, CM Villalón, CM Villalón, CN Sang, CY Yu, D Centurión, D Hoyer, D Hoyer, D Sarsero, DA Curran, David Centurión, DB Bylund, DB Bylund, DB Bylund, DB Bylund, DB Bylund, DD Mitsikostas, DD Mitsikostas, DE Dluzen, DJ Goldstein, DJ Goldstein, DJ Goldstein, DL Jackson, DM Pérez, DR Poyner, DR Thomas, DR Thomas, DS Millson, DW Dodick, E Del Bene, E Enmark, E Fabbretti, E Fusayasu, E Tronvik, EA Barnard, EA MacGregor, EA MacGregor, EA MacGregor, EA MacGregor, EM Cassidy, EW Willems, EW Willems, EW Willems, EW Willems, F Facchinetti, F Facchinetti, F Marceau, F Martínez, FG Freitag, FM Cutrer, FM Cutrer, FM Cutrer, G Attali, G Burnstock, G D’Andrea, G Trapani Di, GA Lambert, GA Michelotti, GL Stiles, GM Terwindt, GW Price, GW Smith, H Doods, H Heyck, H Kaube, H Kowa, H Schrader, HC Diener, HM Vargas, HO Kalkman, HS Blaxall, I Jansen-Olesen, I Mody, IH Page, IT Forbes, J Galitzky, J Honkaniemi, J Olesen, J Olesen, JA Charles, JA Terrón, JB Becker, JC Jen, JC Shih, JD Carroll, JD Classey, JE Palmer, JJ Fernández-Ruíz, JL Brandes, JM Brundege, JM Cruickshank, JM Orshal, JP Dreier, JP Hieble, JP Hieble, JR Arch, JR Clements, JR Docherty, JR Fozard, JW Lomasney, JW Regan, K Kapoor, K Schmuck, K Zimmermann, KA Krobert, KA Petersen, KA Petersen, Kayi Y. Chan, KI Roon, KJ Powell, KL Hoskin, KMA Welch, KP Lesch, KR Oliver, KW Johnson, L Edvinsson, L Edvinsson, L Hein, LA Phebus, LE Limbird, LH Lassen, LH Lassen, LH Lassen, LJ Smith, LL Ven van de, LM McLatchie, M Anthony, M Anthony, M Boccuni, M Cyr, M Farkkila, M Gasparo De, M Hasselblatt, M Iovino, M Kallela, M Mochi, M Oshita, M Peeters, M Quartu, M Spedding, M Yanagisawa, MA Moskowitz, MA Moskowitz, MD Ferrari, MD Ferrari, ME Bigal, ME Erdal, ME Moreau, MG Garry, MG Hanna, MJ Kelly, ML Hernández, MM Rapport, MT Piascik, NG Bowery, NJ Colson, NJ Colson, NJ Giffin, NM Barnes, NM Ramadan, NM Ramadan, NM Ramadan, NT Mathew, O Blin, P Barbanti, P Barbanti, P Geppetti, P Kastner, P Roffey, P Sarchielli, P Sarchielli, P Tfelt-Hansen, P Tfelt-Hansen, P Vries De, P Vries De, PD Drummond, PD Drummond, PJ Goadsby, PJ Goadsby, PJ Goadsby, PJ Goadsby, PJ Goadsby, PJ Goadsby, PJ Goadsby, PJ Goadsby, PL Durham, PP Lakhlani, PR Saxena, PR Saxena, PR Saxena, PR Saxena, Pramod R. Saxena, PT Hurley, QP Ma, R Burstein, R Cerbo, R Hering-Hanit, R Lodi, R Quirion, R Rabkin, R Uddman, R Würz, RA Bond, RA Ophoff, RB Lipton, RB McCall, RE Widdop, RJ Storer, RJ Storer, RJ Storer, RL Weinshank, RO Millán-Guerrero, RO Millán-Guerrero, RP Ahlquist, RW Kimball, RWM Broek van den, S Akerman, S Akerman, S Akerman, S Akerman, S Akerman, S Cotecchia, S Ghelardoni, S Gupta, S Gupta, S Gupta, S Maude, S Mehrotra, S Mehrotra, S Nag, S Paterna, S Shepheard, S Stellar, Saurabh Gupta, SD Brain, SD Silberstein, SD Silberstein, SD Silberstein, SG Hamilton, SJ Hill, SJ Peroutka, SJ Peroutka, SJ Peroutka, SJ Peroutka, SJ Peroutka, SJ Peroutka, SJ Tallaksen-Greene, SJ Tepper, SM Lanier, SP Alexander, SP Cook, SP Cook, ST Lee, Suneet Mehrotra, T Attina, T Ishida, T Ishida, T Matsubara, T Takenaka, TJ Murphy, TM Buchanan, TW Ho, U Arulmani, U Arulmani, U Arulmani, V Erspamer, V Erspamer, V Johannsson, V Limmroth, V Shaygannejad, V Simonneaux, VT Martin, W Chai, WF Stewart, WI Bender, WL Hasler, WM Herrmann, WS Lee, Y Dumont, Y Sahara, Y Zhang, YT Lau, Z Cohen, Z Zhang   +335 more
core   +5 more sources

Alpha‐2‐adrenoreceptor agonists as analgesic drugs in equine medicine

Equine Veterinary Education, EarlyView.
Summary Managing pain in horses is challenging despite the availability of nonsteroidal anti‐inflammatory drugs, local anaesthetics, opioids and α2‐adrenoreceptor agonists. While α2‐agonists are widely used for sedation and restraint, their analgesic properties remain underutilised.
J. A. E. Hubbell, J. Brandly, W. W. Muir III, J. Page, K. Hopster   +4 more
wiley   +1 more source

Controlled Resistant Hypertension Following A Successful Renal Artery Stenting: A Rare Case Report in A Developing Country

Majalah Kardiologi Indonesia
Background Renal artery stenosis is among the etiologies of secondary hypertension in which the diagnosis and therapy are difficult. We report a case of a patient with uncontrollable hypertension with frequent episodes of malignant hypertension ...
Fatihatul Firdaus Munita, Badai Bhatara Tiksnadi, Januar Wibawa Martha, Margareta Ginanti Ratna   +3 more
doaj   +1 more source

Aetiological relevance of haematological, biochemical and endocrine parameters on equine odontoclastic tooth resorption and hypercementosis (EOTRH)

Equine Veterinary Journal, EarlyView.
Abstract Background The dental syndrome EOTRH is a painful, progressive dental disease with an unknown aetiology. The often painful nature of EOTRH emphasises the need for a better knowledge of the underlying pathogenic mechanism and risk factors. A comparative analysis of haematological, biochemical and endocrine values in EOTRH‐affected and non ...
Melusine Tretow, Anna M. Hain, Astrid Bienert‐Zeit   +2 more
wiley   +1 more source