Results 171 to 180 of about 42,588 (295)

CARD9 Conveys Pancreatic Islet Sympathetic Nervous β2 Signals to Reshape Macrophage Creatine Metabolism in Type 1 Diabetes

Advanced Science, Volume 13, Issue 3, 14 January 2026.
This study identifies CARD9 as a key mediator linking sympathetic β2‐adrenergic receptor signaling to macrophage creatine metabolism, inflammatory polarization, and neuronal integrity. Loss of β2‐AR‐PKA‐CREB1‐CARD9 signaling in macrophages reduces creatine uptake, promotes pro‐inflammatory macrophage activation, and drives sympathetic axon ferroptosis.
Huimin Yuan, Senlin Li, Shuai Liu, Hong Zhou, Yue Xu, Wenhui Li, Mengxuan Wang, Mengheng Wang, Mengzhu Zheng, Wenxi Shi, Xin Li, Yiting Feng, Ming Xiang   +12 more
wiley   +1 more source

Pharmacological Interventions for Orthostatic Hypotension: A Systematic Review. [PDF]

Cureus
Verma A, Saraya E, Haque MS, Senaratne M, Khan S, Kasagga A, Malasevskaia IA.   +6 more
europepmc   +1 more source

A Regional Approach to a Global Challenge: A Case Report of Caudal Anesthesia for Anoplasty in Tetralogy of Fallot With Pulmonary Atresia

Clinical Case Reports, Volume 14, Issue 1, January 2026.
Timeline of the patient's clinical course from birth to follow‐up: (birth, diagnosis, NICU admission, prostaglandin infusion, surgery date, post‐op NICU stay, discharge and 3 month follow‐up). ABSTRACT Patients with Tetralogy of Fallot (TOF) with pulmonary atresia present high perioperative risks during non‐cardiac surgeries, making anesthetic ...
Prince Barnawal, Rukesh Yadav, Sandeep Khatri, Jyoti K. C. Khatri, Sudarshan Acharya   +4 more
wiley   +1 more source

Hydrogen Sulfide and Nitric Oxide Improve Renal Function and α-Adrenergic Responsiveness in Rats with Left Ventricular Hypertrophy. [PDF]

Curr Issues Mol Biol
Fatima T, Shammari LA, Lazhari MI, Alrohily W, Yong Chia T, Alsabeelah N, Alanazi EF, Almutairi KA, Alhabradi SM, Alharbi NS, Ahmad A.   +10 more
europepmc   +1 more source

Pyroptosis in Peripheral Neuropathy: From Molecular Mechanisms to Therapeutic Targeting

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Pyroptosis is a key inflammatory cell death pathway in peripheral neuropathy, with opposing roles: it perpetuates neuropathic pain but can be induced to kill neuroblastoma cells. This review consolidates mechanistic understanding and therapeutic strategies, arguing for a shift from disease‐centric to target‐centric treatment approaches to improve ...
Jinhuan Wei, Mingyue Liuyuan, Zhixin Ye, Xueying Wang, Xueli Zhou, Yifan Shan, Cheng He, Chunting Zhu, Chicheng Zhou, Jingyin Bao, Yonghui Zhang, Gang Chen   +11 more
wiley   +1 more source

Role of Macrophages in Cardiac Remodeling: Cues From Zebrafish Heart

Immunity, Inflammation and Disease, Volume 14, Issue 1, January 2026.
The figure illustrates the role of macrophage polarization in cardiac damage and repair, highlighting monocyte to M0, M1, and M2 macrophage differentiation. M1 macrophages, in response to pro‐inflammatory cytokines (e.g., IFNγ, TNF‐α, IL‐6), are involved in fibrosis and scarring in the heart.
Himanshu Gaur, Maram Hasan, Huseyin C. Yalcin   +2 more
wiley   +1 more source

β₂-Adrenergic Receptor Agonists in Diabetic Kidney Disease: Exploring a New Frontier. [PDF]

Biochem Res Int
Hegde S, Chogtu B, Magazine R, Magazine R, Prabhu R.   +4 more
europepmc   +1 more source

Differential mechanisms of action of the trace amines octopamine, synephrine and tyramine on the porcine coronary and mesenteric artery [PDF]

, 2019
Chess-Williams, Russ, Koh, Andy, Lohning, Anna Elizabeth   +2 more
core   +1 more source

Integrated Analysis of the Immune Infiltration Pattern and Novel Diagnostic Biomarkers in Septic Cardiomyopathy

Immunity, Inflammation and Disease, Volume 14, Issue 1, January 2026.
In this study, various informatics analyses were employed to identify hub genes associated with the onset of septic cardiomyopathy and investigate its immune infiltration status. ABSTRACT Purpose In this study, various informatics analyses were employed to identify the hub genes associated with septic cardiomyopathy (SCM) onset and investigate their ...
Wei Liu, Xi Zheng, Dong Wang, Jingyi Wang, Xincheng Li, Fei Li, Wenxiong Li, Jin Zhang   +7 more
wiley   +1 more source

Chronic stress-related neuroendocrine mediators and ovarian cancer. [PDF]

Discov Oncol
Du H, Yu G, Hu R, Du J, Liu C.
europepmc   +1 more source