Results 201 to 210 of about 42,588 (295)

Alcohol and the endocrine system: A critical review of disruptions, potential mechanisms, and health implications

Alcohol, Clinical and Experimental Research, Volume 50, Issue 1, January 2026.
The endocrine system coordinates whole body cellular function and maintains homeostasis. Alcohol impacts the integrity of endocrine regulation at multiple sites, contributing to risk for comorbidities. Some of the alcohol‐mediated pathophysiological effects on the endocrine system include alterations in receptor expression and responsiveness, protein ...
Patricia E. Molina, Liz Simon
wiley   +1 more source

Mechanisms of alveolar type II epithelial cells' mitochondrial quality control during acute lung injury/acute respiratory distress syndrome: bridging the gap between oxidative stress, inflammation, and fibrosis. [PDF]

Front Physiol
Zeng L, Yan J.
europepmc   +1 more source

Adjuvant pharmacological strategies for the musculoskeletal system during long‐term space missions

British Journal of Clinical Pharmacology, Volume 92, Issue 1, Page 11-23, January 2026.
Abstract Despite 2 h of daily exercise training, muscle wasting and bone loss are still present after 6‐month missions to the international space station. Some crew members lose bone much faster than others. In preparation for missions to the Moon and Mars, space agencies are therefore reviewing their countermeasure portfolios.
Friederike Thomasius, Dominik Pesta, Jörn Rittweger   +2 more
wiley   +1 more source

The role of α₂-adrenergic mechanisms in sympathetic baroreflex control of human blood pressure. [PDF]

Am J Physiol Heart Circ Physiol
Spafford JE, Limberg JK, Harvey RE, Wiggins CC, Iannarelli NJ, Senefeld JW, Nicholson WT, Curry TB, Joyner MJ, Shoemaker JK, Baker SE, Klassen SA.   +11 more
europepmc   +1 more source

Central Nervous System Depression After Topical Administration of Brimonidine Eye Drops to Induce Vomiting in a Cat. [PDF]

Vet Med Sci
Kim D, Jun J, Park E, Jung J, Son WG.
europepmc   +1 more source

Pharmacotherapy Risks in Rare Genetic Diseases: Cross‐Referencing ACMG Secondary Findings v3.2 List With Clinical Databases

Clinical and Translational Science, Volume 19, Issue 1, January 2026.
ABSTRACT Clinical genomics and pharmacogenomics have largely remained separate fields, though some genetic variants have overlapping disease risk and drug implications. However, the extent of this overlap is not well studied. To explore this gap, we cross‐referenced genes from the American College of Medical Genetics Secondary Findings v3.2 list with ...
Josiah D. Allen, Benjamin Q. Duong, Jordan Brady, Pamela Arn   +3 more
wiley   +1 more source

Autonomic nervous system dysfunction in chronic obstructive pulmonary disease: mechanistic insights and therapeutic implications. [PDF]

Ann Med
Chen D, Zhou Z, Zhou Z, Zhao L, Chen Y.
europepmc   +1 more source

Sympatho‐modulatory therapies in perioperative medicine [PDF]

, 2017
Schaub, M. C., Schulz, C., Wacker, J., Zaugg, M.   +3 more
core  

Effects of vatinoxan on gastrointestinal motility, sedation, and antinociception during and after long‐lasting detomidine infusion in horses

Equine Veterinary Journal, Volume 58, Issue 1, Page 212-219, January 2026.
Abstract Background Sedation in horses is typically achieved using alpha‐2 adrenoceptor agonists, although their use is associated with multiple side effects. A peripheral alpha‐2 adrenoceptor antagonist, vatinoxan, can alleviate many of these. Objectives To evaluate the effects of vatinoxan infusion on gastrointestinal motility, sedation, and ...
Bartlomiej Obrochta, Heidi Tapio, Marja Raekallio, Luis Alfonso Gracia Calvo, Rebecca Rivera Pöyhönen, Kati Hagman, Noora Jantunen, Ninja Karikoski   +7 more
wiley   +1 more source

Advances in the treatment of malignant tumors with neurological drugs. [PDF]

Discov Oncol
Li Y, Na J, Zhong L, Zhao Y.
europepmc   +1 more source