Results 131 to 140 of about 46,059 (254)

The Genetic Blueprint of Obesity: From Pathogenesis to Novel Therapies

Obesity Reviews, EarlyView.
ABSTRACT Obesity is a chronic metabolic disease characterized by disturbances in energy homeostasis, leading to excessive fat accumulation. The pathogenesis of the disease is shaped by a complex interplay of genetic, epigenetic, biological, psychological, and environmental factors.
Gašper Tonin, Stjepan Eržen, Zala Mlinarič, Dubravka Jurišić Eržen, Simon Horvat, Tanja Kunej, Jasna Klen   +6 more
wiley   +1 more source

Alpha-1 Adrenergic Agonists for the Prevention of Floppy Iris Syndrome [PDF]

, 2013
Gianluca Carifi, Nikolaos Kopsachilis
openalex   +1 more source

Guanabenz in the horse – A preliminary report on clinical effects and comparison to clonidine and other alpha-2 adrenergic agonists

, 2022
A F Lehner, Levent Dirikolu, T Tobin
openalex   +2 more sources

Up-regulation of a thermogenesis-related gene (UCP1) and down-regulation of PPARgamma and aP2 genes in adipose tissue: possible features of the antiobesity effects of a beta3-adrenergic agonist. [PDF]

, 2001
A number of experiments have demonstrated the antiobesity effects of beta(3)-adrenergic receptor stimulation by promoting thermogenesis and/or lipolysis.
Larrarte, E. (Eider), Margareto, J. (Javier), Marti, A. (Amelia), Martinez, J.A. (José Alfredo)   +3 more
core  

Contribution of Sympathetic Sensory Coupling to Craniofacial Nociception

Orthodontics &Craniofacial Research, EarlyView.
ABSTRACT Stress and anxiety are associated with increased pain intensity in temporomandibular disorders (TMDs) patients. It is possible that this association is due to a direct interaction between the sympathetic and sensory nervous systems. This narrative review examines evidence for a potential sympathetic sensory interaction in deep craniofacial ...
Brian Edwin Cairns
wiley   +1 more source

Use of Alpha-2 Adrenergic Agonists to Improve Surgical Field Visibility In Ear And Nasal Surgery: A Systematic Review [PDF]

, 2015
María Ángeles Quijada-Manuitt, Antonio Vallano, Alda Cardesín, Yolanda Escamilla, Caridad Pontes   +4 more
openalex   +1 more source

Reversal of mitochondrial dysfunction and right ventricular failure after chronic treatment with alpha-1A-adrenergic agonist

, 2022
On Yeung Li, Guanying Wang, Philip M. Swigart, Bahador Marzban, Paul Simpson, Naomi C. Chesler, Daniel Beard, Anthony J. Baker   +7 more
openalex   +1 more source

Pharmacokinetic and Pharmacodynamic Modeling of Clonidine and Midazolam for Sedation in Pediatric Intensive Care

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Clonidine and midazolam are routinely used in the pediatric intensive care unit for pain and sedation management, but target concentration and optimal dose are poorly defined for both drugs. The CloSed study is a multicenter, double‐blind, randomized, active‐controlled noninferiority trial with a 1:1 randomization between clonidine ...
Maddlie Bardol, Yucheng Sheng, Manuel Baarslag, Adriana Ceci, Frank Dörje, Mari‐Liis Ilmoja, Peter Larsson, Per‐Arne Lönnqvist, Tuuli Methsvat, Pavla Pokorna, Wolfgang Rascher, Joost van Rosmalen, Michael Schroth, Alessandra Simonetti, Dick Tibboel, Irmgard Toni, Catherine Tuleu, Thomas M. K. Völkl, Brian J. Anderson, Stefan Wimmer, Joseph F. Standing, Antje Neubert, CloSed Consortium   +22 more
wiley   +1 more source

Effects of perioperative dexmedetomidine on delayed graft function following renal transplant: a systematic review and meta-analysis

Brazilian Journal of Anesthesiology
Background: Dexmedetomidine, a highly selective alpha-2 adrenoceptor agonist with sedative and analgesic effects, has been suggested in recent studies to possess renoprotective properties.
Ka Ting Ng, Wei En Lim, Wan Yi Teoh, Soo Kun Lim, Ahmad Nazran bin Fadzli, Pui San Loh   +5 more
doaj   +1 more source

Cervical epidural catheter for administration of detomidine and morphine in a model of carpal synovitis in the horse

Veterinary Surgery, EarlyView.
Abstract Objective To determine the analgesic effects of detomidine and morphine administered by cervical epidural catheter (CEC) on a model of thoracic limb pain. Study design Prospective, randomized, blinded crossover study. Animals Five adult horses.
Veronica L. Edwards, Rachel Reed, Michael Perlini, Valerie J. Moorman   +3 more
wiley   +1 more source