Results 131 to 140 of about 79,434 (274)

The alpha-2 adrenergic agonist, UK 14,304, inhibits growth andincreases apoptosis of the cholangio-carcinoma cell line, Mz-Cha-1, through camp but not Ca2+-dependent mechanisms

open access: bronze, 2000
Noriatsu Kanno   +6 more
openalex   +1 more source

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies.
Silvia Marchianò   +18 more
wiley   +1 more source

Trends in first‐line monotherapy and combination therapy for hypertension in UK primary care

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 457-467, February 2026.
Aims Debate remains about the optimal initial treatment strategy for hypertension. Most guidelines recommend first‐line combination therapy for most patients. However, the UK's National Institute for Health and Care Excellence recommends first‐line monotherapy for all patients.
Kyle Johnson   +4 more
wiley   +1 more source

Alpha-2 Adrenergic Agonists Reduce Heavy Alcohol Drinking and Improve Cognitive Performance in Mice [PDF]

open access: gold
Sema G Quadir   +9 more
openalex   +1 more source

Efficacy of Topical Beta‐Blockers in Managing Epidermal Growth Factor Receptor Inhibitor‐Related Paronychia and Pyogenic Granuloma‐Like Lesion: A Systematic Review and Meta‐Analysis

open access: yesCancer Medicine, Volume 15, Issue 2, February 2026.
The meta‐analysis, involving with 96 patients, shows high overall response rate with favorable safety to use topical beta‐blockers for epidermal growth factor receptor inhibitors‐induced periungual side effects. Subgroups of lung cancer or solution formation had lower complete response rate, while tyrosine kinase inhibitor and female patients had ...
Po‐Kai Chan   +2 more
wiley   +1 more source

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