Results 141 to 150 of about 79,434 (274)

Neuro‐Immune Crosstalk: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo   +11 more
wiley   +1 more source

Utility of an alpha-1 adrenergic agonist in the management of chylothorax: a case series and management algorithm

open access: gold
Rubén Peralta   +5 more
openalex   +2 more sources

A Phase 3 placebo-controlled, double-blind, multi-site trial of the alpha-2-adrenergic agonist, lofexidine, for opioid withdrawal☆

open access: green, 2008
Elmer Yu   +9 more
openalex   +1 more source

Peripheral Nerves in Cancer: Regulatory Roles and Therapeutic Strategies

open access: yesMedComm, Volume 7, Issue 2, February 2026.
The interaction between cancer cells and peripheral nerves: (1) tumor cells could induce the growth of new neural axons and constructing a neural fiber network within the tumor tissue through secreting nerve growth factors; (2) nerve‐derived bioactive molecules can induce perineural invasion of tumor and regulate the malignant phenotype of tumor, such ...
Yan Fu   +6 more
wiley   +1 more source

Preventive Effect of Preoperative Intranasal Dexmedetomidine for Postoperative Delirium in Elderly Patients with Sleep Disorders Undergoing Major Noncardiac Surgery: A Randomized, Triple-Blind, Placebo-Controlled Trial

open access: yesDrug Design, Development and Therapy
Chao Chen,1,2,* Ruixue Zhai,1,2,* Shengfeng Yang,3,* Xinglong Xiong,1,2 Jun Lu,1,2 Guangling Tang,1,2 Sijie Tang,1,2 Yewei Shi,1,2 Zhenyan Zhu,1,2 Dongxu Chen,4 Jing Shi1,2 1Department of Anesthesiology, Affiliated Hospital of ...
Chen C   +10 more
doaj  

Deceptive beauty of non‐natural structures

open access: yesProtein Science, Volume 35, Issue 2, February 2026.
Abstract Structures of proteins and multiprotein complexes are considered landmark achievements. However, in many cases, mutant proteins are used for structural work. Even when wild type proteins are used, crystallization or complex formation for cryoEM is performed in highly nonphysiological conditions.
Vsevolod V. Gurevich   +1 more
wiley   +1 more source

Thermogenic Targets for Obesity Management in the Era of Incretin-Based Therapies. [PDF]

open access: yesPharmaceuticals (Basel)
Soliman S   +3 more
europepmc   +1 more source

Agonist-dependent phosphorylation of the alpha 2-adrenergic receptor by the beta-adrenergic receptor kinase.

open access: hybrid, 1987
J.L. Benovic   +7 more
openalex   +1 more source

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