Results 191 to 200 of about 104,693 (298)

Effects of vatinoxan on gastrointestinal motility, sedation, and antinociception during and after long‐lasting detomidine infusion in horses

open access: yesEquine Veterinary Journal, Volume 58, Issue 1, Page 212-219, January 2026.
Abstract Background Sedation in horses is typically achieved using alpha‐2 adrenoceptor agonists, although their use is associated with multiple side effects. A peripheral alpha‐2 adrenoceptor antagonist, vatinoxan, can alleviate many of these. Objectives To evaluate the effects of vatinoxan infusion on gastrointestinal motility, sedation, and ...
Bartlomiej Obrochta   +7 more
wiley   +1 more source

Preventive Effect of Preoperative Intranasal Dexmedetomidine for Postoperative Delirium in Elderly Patients with Sleep Disorders Undergoing Major Noncardiac Surgery: A Randomized, Triple-Blind, Placebo-Controlled Trial

open access: yesDrug Design, Development and Therapy
Chao Chen,1,2,* Ruixue Zhai,1,2,* Shengfeng Yang,3,* Xinglong Xiong,1,2 Jun Lu,1,2 Guangling Tang,1,2 Sijie Tang,1,2 Yewei Shi,1,2 Zhenyan Zhu,1,2 Dongxu Chen,4 Jing Shi1,2 1Department of Anesthesiology, Affiliated Hospital of ...
Chen C   +10 more
doaj  

Pharmacological Interventions for Orthostatic Hypotension: A Systematic Review. [PDF]

open access: yesCureus
Verma A   +6 more
europepmc   +1 more source

Expanding the Immunologic and Neuronal Landscape of IgE‐Mediated Anaphylaxis

open access: yesImmunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Anaphylaxis is a life‐threatening immunoglobulin E (IgE)‐mediated type I hypersensitivity reaction with rising prevalence and burden. It involves mast cell degranulation upon cross‐linking of antigen on mast cell‐bound IgE. Mechanisms of IgE‐mediated anaphylaxis remain incompletely understood, particularly the induction of systemic symptoms ...
Ruchi Biswas   +2 more
wiley   +1 more source

Drug Interactions With Excessive Daytime Sleepiness Treatments. [PDF]

open access: yesJ Pharm Technol
Thomas SV   +3 more
europepmc   +1 more source

Cyanines Substituted on the Polymethine Chain: Synthesis, Resulting Properties, and Application Use Cases

open access: yesChemPlusChem, Volume 90, Issue 12, December 10, 2025.
Cyanines are small‐molecule dyes with a polymethine chain. For various applications, their properties can be tuned by varying not only chain length and auxochrome end groups but also the substituents on the polymethine chain. Here, we review the synthesis, properties, and applications of cyanines with substituents on the polymethine chain.
Rebecca Strada   +2 more
wiley   +1 more source

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