Results 181 to 190 of about 984,866 (243)

Neural regulation in lung cancer: from mechanisms to new therapeutic perspectives. [PDF]

open access: yesClin Exp Med
Zhao J   +10 more
europepmc   +1 more source

Barriers and facilitators to detoxification from opioid substitution treatment: A mixed‐methods systematic review

open access: yesAddiction, Volume 121, Issue 10, Page 2607-2619, October 2026.
Abstract Background and aims Despite the well‐documented benefits of opioid substitution treatment (OST) in treating opioid dependence (OD), many people diagnosed with OD desire to live a drug‐free life. The transition to abstinence involves detoxification: a gradual dose reduction of OST to zero milligrams.
Amy Bagshaw   +5 more
wiley   +1 more source

ATP Release and Purinergic Signaling Potentiate β‐Adrenergic Effects on Brown Adipocytes

open access: yesActa Physiologica, Volume 242, Issue 10, October 2026.
ABSTRACT Aim Brown adipose tissue (BAT) specializes in energy consumption and thermogenesis in response to cold stress. Brown adipocytes (BA) express purinergic receptors, yet little is known about the source of extracellular ATP and the role of purinergic signaling, and the potential interaction with β‐adrenergic signaling.
Marco Tozzi   +8 more
wiley   +1 more source

Severity of Cardiovascular Autonomic Neuropathy Is Linked to Increasing Levels of Circulating Proinflammatory Cytokines

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 8847-8860, October 2026.
ABSTRACT Aims Cardiovascular autonomic neuropathy (CAN) is a severe form of diabetic neuropathy affecting approximately one in five people with diabetes and is a major predictor of cardiovascular mortality. Low‐grade inflammation may contribute to CAN development, but the exact inflammatory factors associated with CAN remain unclear.
Michelle Damgaard   +9 more
wiley   +1 more source

Updates in COPD Management: From Inflammatory Pathways to Targeted Therapies

open access: yesEuropean Journal of Clinical Investigation, Volume 56, Issue 10, October 2026.
COPD is a heterogeneous disease driven by overlapping neutrophilic and eosinophilic inflammatory pathways. This review highlights the shift from symptom‐based treatment toward phenotype‐ and biomarker‐directed care. Blood eosinophils, FeNO, and IgE predict corticosteroid responsiveness and identify candidates for biologic therapy.
Sasha Raman   +3 more
wiley   +1 more source

Complications and outcomes of standing flank versus ventral midline laparotomy for equine nephrosplenic entrapment

open access: yesEquine Veterinary Education, Volume 38, Issue 10, Page e736-e743, October 2026.
Summary Background Nephrosplenic entrapment (NSE) is a common surgical colic in horses. Ventral midline laparotomy (VML) under general anaesthesia (GA) is the standard approach, whereas standing flank laparotomy (SFL) is an alternative approach for surgical correction. However, direct comparisons between these approaches are lacking.
V. Santalucia   +5 more
wiley   +1 more source

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