Results 81 to 90 of about 17,930 (241)

Effect of the Arg16Gly β2‐Adrenergic Receptor Polymorphism on Long‐Term Mepolizumab Response and Clinical Remission in Severe Eosinophilic Asthma: A Genotype‐Stratified, Multicenter Study

Allergy, EarlyView.
This study examines the association between the rs1042713 (Arg16Gly) polymorphism of the β2‐adrenergic receptor and the risk of severe eosinophilic asthma, as well as its influence on mepolizumab long‐term effectiveness and clinical remission. The Arg16 allele is associated with increased risk of severe disease and potentially diminished long‐term ...
Santi Nolasco, Evelina Fagone, Raffaele Campisi, Andrea Portacci, Giulia Scioscia, Corrado Pelaia, Angelantonio Maglio, Claudio Candia, Vitaliano Nicola Quaranta, Isabella Carrieri, Alessandro Saglia, Alessandro Vatrella, Girolamo Pelaia, Carlo Vancheri, Maria Pia Foschino Barbaro, Maria D'Amato, Giovanna Elisiana Carpagnano, Nunzio Crimi, Claudia Crimi, on behalf of the Southern Italy Network on Severe Asthma Therapy, Rossella Intravaia, Morena Porto, Pietro Impellizzeri, Maria Provvidenza Pistorio, Fabio Vignera, Andrea Alessia Nardo, Concetta Giannì, Silvano Dragonieri, Flogerta Sana, Valeria Pezzuto, Santina Ferulli, Massimo Triggiani, Roberta Parente, Pasquale Tondo, Piera Soccio, Donato Lacedonia, Luigi Ciampo, Antonio Franzese, Valeria Longobardi   +38 more
wiley   +1 more source

Peer Review #1 of "Effects of chronic prazosin, an alpha-1 adrenergic antagonist, on anxiety-like behavior and cortisol levels in a chronic unpredictable stress model in zebrafish (Danio rerio) (v0.1)"

, 2020

openalex   +1 more source

Dorsal Genital Nerve Stimulation as an Adjunctive Therapy to Control Neurogenic Detrusor Overactivity After Spinal Cord Injury

Artificial Organs, EarlyView.
People with spinal cord injury (SCI) experience bladder overactivity, which can cause incontinence. Dorsal genital nerve stimulation (DGNS) can suppress overactivity, providing a longer duration to reach a toilet. People with SCI trialed home‐based DGNS for 8 weeks. DGNS was effective in the laboratory, and participants found home‐based DGNS acceptable.
Sean Doherty, Evangeline Martinez, Sarah Knight, Richard Nobrega, Lynsey Duffell   +4 more
wiley   +1 more source

Alpha-1 Adrenergic-Antagonist Use Increases the Risk of Sleep Apnea: A Nationwide Population-Based Cohort Study [PDF]

, 2019
Po‐Lan Su, Wen-Kuei Lin, Cheng-Yu Lin, Sheng‐Hsiang Lin   +3 more
openalex   +1 more source

Aniridia‐associated keratopathy: Clinical and molecular mechanisms of disease progression and emerging therapeutic targets

Acta Ophthalmologica, EarlyView.
Abstract Congenital aniridia is a rare genetic disorder primarily caused by pathogenic variants of the PAX6 gene. It leads to various panocular anomalies, including aniridia‐associated keratopathy (AAK). This review highlights recent insights into its pathogenesis, focusing on clinical staging, microstructural changes in the cornea and molecular ...
N. Szentmáry, S. Suiwal, M. Amini, F. N. Fries, A. Náray, L. Latta, Z. Li, S. Li, S. Liu, S. L. Hsu, S. Kundu, G. Tóth, S. Trusen, J. Zimmermann, B. Seitz, B. Käsmann‐Kellner, Z. Hoxha, A. Langenbucher, O. Stachs, M. Cortón‐Perez, K. Tory, A. Csorba, Z. Z. Nagy, M. C. Acosta, J. Gallar, M. Csidey, E. Maka, T. Stachon   +27 more
wiley   +1 more source

Topical administration of adrenergic receptor pharmaceutics and nerve growth factor

Clinical Ophthalmology, 2010
Jena J SteinleDepartments of Ophthalmology and Anatomy and Neurobiology, Hamilton Eye Institute, University of Tennessee Health Science Center, Memphis, TN 38163, USAAbstract: Topical application of nerve growth factor (NGF) and adrenergic receptor ...
Jena J Steinle
doaj  

Add-On Effect of Bedtime Dosing of the .ALPHA.1-Adrenergic Receptor Antagonist Doxazosin on Morning Hypertension and Left Ventricular Hypertrophy in Patients Undergoing Long-Term Amlodipine Monotherapy [PDF]

, 2007
Toshio Ikeda, Tomoko Gomi, Yuko Shibuya, Shingo Shinozaki, Yoshifumi Suzuki, Nami Matsuda   +5 more
openalex   +1 more source

GDF15: Anxiety Signalling From the Adipose Tissue

iNew Medicine, EarlyView.
Song‐Yang Zhang
wiley   +1 more source

Across species: A comparative perspective on red cell homeostasis and its influence on our understanding of human physiology and disease

British Journal of Haematology, EarlyView.
This review highlights how studies on animal red cells have enriched our understanding of the behaviour of those from humans. A comparative perspective has enhanced our knowledge of human red cell pathophysiology Summary This review emphasises how studies on animal red cells have enriched our understanding of the behaviour of those from humans.
Kathleen M. Connolly, Pengyi Ding, Rasiqh Wadud, David C. Rees, John N. Brewin, John S. Gibson   +5 more
wiley   +1 more source

Peer Review #2 of "Effects of chronic prazosin, an alpha-1 adrenergic antagonist, on anxiety-like behavior and cortisol levels in a chronic unpredictable stress model in zebrafish (Danio rerio) (v0.2)"

, 2020
Soaleha Shams
openalex   +2 more sources