Results 151 to 160 of about 92,710 (320)
Experimental Physiology, EarlyView.Abstract Cardiopulmonary bypass (CPB) in cardiac surgery is associated with a high risk of postoperative neurological complications. Perioperative use of vasopressors is common to counteract arterial hypotension in this setting. However, use of α‐agonist vasopressors has been associated with cerebral desaturations.
Edouard Marques +7 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend The carotid body develops aberrant high activity in chronic heart failure, resistant hypertension, obstructive sleep apnoea (OSA) and diabetes. Hyperactivity of the carotid body leads to both high tonicity and increased sensitivity of the arterial chemoreflex with resultant sympathoexcitation.
Tymoteusz Żera +7 more
wiley +1 more source
Endothelial TRPV4–Cx43 signalling complex regulates vasomotor tone in resistance arteries
The Journal of Physiology, EarlyView.Abstract figure legend In this study, we investigate, for the first time, the role of endothelial Cx43 hemichannels (hCx43) in the regulation of vasomotor tone. We discovered that TRPV4 channels and Cx43 are in proximity within the endothelium of mouse arterioles.
Pía C. Burboa +7 more
wiley +1 more source
Exploring neuronal mechanisms of osteosarcopenia in older adults
The Journal of Physiology, EarlyView.Abstract figure legend The mechanosensitive osteocytic network within the bone matrix acts as a receptor and plays a crucial role in the functional adaptation of bone to mechanical loading. Through mechanotransduction, osteocytes convert mechanical impulses into electrical signals, which are transmitted via afferent nerves to sympathetic preganglionic ...
Ilhan Karacan, Kemal Sıtkı Türker
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend The Kcna1 knockout mouse model of sudden unexpected death in epilepsy (SUDEP) exhibits sex‐specific differences in SUDEP risk. Female mice exhibit a lower SUDEP risk than males, despite similar seizure characteristics and interictal cardiac function across sexes.
Kelsey Paulhus +11 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, Volume 117, Issue 5, Page 1254-1263, May 2025.The No‐POPPY study (NCT03396588), a double‐blind, randomized trial compared morphine with clonidine therapy for neonatal opioid withdrawal syndrome (NOWS) and found that the duration of treatment was similar across groups. This is significant because perinatal use of morphine has the potential for neurodevelopmental consequences.
Fei Tang +4 more
wiley +1 more source
PROFITABILITY OF USING SALBUTAMOL (A BETA-ADRENERGIC AGONIST) AS A GROWTH PROMOTER OF BROILER CHICKENS [PDF]
, 2016 Mohammed A. Aziz +2 more
openalex +1 more source
α‐Synuclein in Parkinson's Disease: From Bench to Bedside
Medicinal Research Reviews, Volume 45, Issue 3, Page 909-946, May 2025.ABSTRACT α‐Synuclein (α‐syn), a pathological hallmark of PD, is emerging as a bridging element at the crossroads between neuro/immune‐inflammatory responses and neurodegeneration in PD. Several evidence show that pathological α‐syn accumulates in neuronal and non‐neuronal cells (i.e., neurons, microglia, macrophages, skin cells, and intestinal cells ...
Gabriele Bellini +8 more
wiley +1 more source