Results 161 to 170 of about 50,860 (258)

Impaired Adipose Anabolism in Pancreatic Cancer Cachexia Is Reversed by HuR Inhibition

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 2, April 2026.
ABSTRACT Background Cachexia is defined by chronic loss of fat and muscle, is a frequent complication of pancreatic ductal adenocarcinoma (PDAC) and negatively impacts patient outcomes. Nutritional supplementation cannot fully reverse tissue wasting, and the mechanisms underlying this phenotype are unclear.
Paige C. Arneson‐Wissink, Katherine Pelz, Beth Worley, Heike Mendez, Peter Pham, Parham Diba, Peter R. Levasseur, Grace McCarthy, Alex Chitsazan, Jonathan R. Brody, Aaron J. Grossberg   +10 more
wiley   +1 more source

Response of human iPSC-cardiomyocytes to adrenergic drugs assessed by high-throughput pericellular oxygen measurements and computational modeling. [PDF]

J Mol Cell Cardiol Plus
Li W, Forouzandehmehr MA, McLeod D, Pozo MR, Heinson YW, Kay MW, Li Z, Morotti S, Entcheva E.   +8 more
europepmc   +1 more source

Facilitating interprofessional collaboration for effective care transitions of a patient with chronic obstructive pulmonary disease

Nutrition in Clinical Practice, Volume 41, Issue 2, Page 435-442, April 2026.
Abstract Transitions of care are the movement of a patient from one care setting or provider to another. Interprofessional collaboration is critical in ensuring patient safety and satisfactory health outcomes. Each time an interprofessional team transfers a patient, the team performs three important roles: representing the patient, providing patient ...
Sara Edwards, Kaitlyn Kolcun, Jeanie Bochenek, Emily Buatois, Monica Robinson, Erin Thomas, Matthew Curtis, Catherine Hechmer, Tracy Taylor, Sheela Thomas   +9 more
wiley   +1 more source

Human cells for human proteins: Isotope labeling in mammalian cells in suspension for functional NMR studies

Protein Science, Volume 35, Issue 4, April 2026.
Abstract In biological and biomedical research, the focus progressively moves towards difficult human proteins, which often can only be expressed in higher eukaryotic cells. Nuclear magnetic resonance (NMR) could contribute significantly to the understanding of important proteins as it is one of the most information‐rich methods.
Philip Rößler, Marco M. Ruckstuhl, Arnelle Löbbert, Timo Stühlinger, Lucia R. Franchini, Ching‐Ju Tsai, Roman Lichtenecker, Binesh Shrestha, Simon H. Rüdisser, Robert Konrat, Gebhard F. X. Schertler, Alvar D. Gossert   +11 more
wiley   +1 more source

Β3-Adrenergic Receptors and Prematurity-Related Diseases: A Systematic Review. [PDF]

Children (Basel)
Fazi C, Dani C.
europepmc   +1 more source

Angiotensin‐(1–7) Alleviates Isoproterenol‐Induced Cardiac Hypertrophy by Suppressing Autophagy and Apoptosis Through the Synergistic Action of Mas Receptor and Angiotensin II Type 2 Receptor

Acta Physiologica, Volume 242, Issue 4, April 2026.
ABSTRACT Aim The aim of this study is to determine whether Angiotensin‐(1–7) [Ang‐(1–7)] alleviates isoproterenol (ISO)–induced cardiac hypertrophy by suppressing excessive autophagy and apoptosis through coordinated Mas receptor (MasR) and angiotensin II type‐2 receptor (AT2R) signaling, and to elucidate the underlying mechanisms.
Xiaomei Wang, Fei Guo, Xiaoqian Wang, Yu Guo, Siyao Fan, Lan Hong, Honghua Jin   +6 more
wiley   +1 more source

Fibre Type-Specific Proteomics Reveals Shared and Distinct Skeletal Muscle Adaptations to Resistance Training and Beta₂-Adrenergic Agonist. [PDF]

J Cachexia Sarcopenia Muscle
Jessen S, Di Credico A, Moreno-Justicia R, Moesgaard L, Lemminger A, Stocks B, Di Baldassarre A, Bangsbo J, Deshmukh AS, Hostrup M.   +9 more
europepmc   +1 more source

3,4‐Methylenedioxymethamphetamine (MDMA) does not induce robust psychomotor activation and 50‐kHz ultrasonic vocalisations in tryptophan hydroxylase 2 (Tph2)‐deficient rats lacking serotonin in the central nervous system

British Journal of Pharmacology, Volume 183, Issue 7, Page 1539-1556, April 2026.
Background and Purpose 3,4‐Methylenedioxymethamphetamine (MDMA), commonly known as ecstasy, is a psychostimulant with entactogenic properties and known to induce arousal and euphoria. As an amphetamine derivate, MDMA acts on the monoamine systems in the brain and stimulates release of dopamine (DA), noradrenaline (NA) and serotonin (5‐HT), yet their ...
Tianhua Wang, Rainer K. W. Schwarting, Markus Wöhr   +2 more
wiley   +1 more source

A systematic review of glucocorticoid use in type 1 diabetes: Glycaemic effects and clinical management strategies

Diabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 2594-2614, April 2026.
Abstract Glucocorticoids (GCs) are widely utilised for the treatment of inflammatory and autoimmune conditions but often precipitate significant hyperglycaemia. People with type 1 diabetes (PWT1D) may be particularly affected due to the challenges of adjusting insulin dosing, for which recommendations remain unclear.
Alexandra Katz, Aidan Shulkin, Asmaa Housni, Amélie Roy‐Fleming, Rémi Rabasa‐Lhoret, Jean‐Francois Yale, Michael A. Tsoukas, Tricia M. Peters, Anne‐Sophie Brazeau   +8 more
wiley   +1 more source

The Comparative Effectiveness of PDE5 Inhibitors and β3 Agonists Versus α-Blockers in Medical Expulsive Therapy for Distal Ureteric Stones: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. [PDF]

Cureus
Ramanah M, Banerjee I, Nunkoo S, Robinson J, Krissheeven M, Banerjee I.   +5 more
europepmc   +1 more source