Results 191 to 200 of about 53,199 (316)

Peripheral Nerves in Cancer: Regulatory Roles and Therapeutic Strategies

open access: yesMedComm, Volume 7, Issue 2, February 2026.
The interaction between cancer cells and peripheral nerves: (1) tumor cells could induce the growth of new neural axons and constructing a neural fiber network within the tumor tissue through secreting nerve growth factors; (2) nerve‐derived bioactive molecules can induce perineural invasion of tumor and regulate the malignant phenotype of tumor, such ...
Yan Fu   +6 more
wiley   +1 more source

Performance-Enhancing Effects of Inhaled Medications: Implications for Heart, Muscle Function, and Doping Detection in Athletes. [PDF]

open access: yesJ Funct Morphol Kinesiol
Cricco R   +9 more
europepmc   +1 more source

Deceptive beauty of non‐natural structures

open access: yesProtein Science, Volume 35, Issue 2, February 2026.
Abstract Structures of proteins and multiprotein complexes are considered landmark achievements. However, in many cases, mutant proteins are used for structural work. Even when wild type proteins are used, crystallization or complex formation for cryoEM is performed in highly nonphysiological conditions.
Vsevolod V. Gurevich   +1 more
wiley   +1 more source

Stabilization versus flexibility: Detergent‐dependent trade‐offs in neurotensin receptor 1 GPCR ensembles

open access: yesProtein Science, Volume 35, Issue 2, February 2026.
Abstract Detergents provide essential membrane‐mimetic environments for studying G protein‐coupled receptors (GPCRs), but their molecular impact on receptor energetics remains incompletely understood. We combined ligand binding, thermostability measurements, and atomistic molecular dynamics to dissect detergent‐ versus ligand‐driven stabilization in a ...
James B. Bower   +6 more
wiley   +1 more source

Comparing the Molecular Pharmacological Properties of Existing β‐Blockers to Determine the Theoretically Most “Ideal” Anti‐Cancer β‐Blocker

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 1, February 2026.
ABSTRACT There is increasing evidence, from cellular, animal and human epidemiological studies, linking β‐blockers with reductions in cancer growth and metastasis. Propranolol is the most investigated β‐blocker for cancer; although as many different off‐patent β‐blockers exist, there is little commercial incentive to drive comparative clinical trials ...
Jillian G. Baker
wiley   +1 more source

Therapeutic Potential of the β3-Adrenergic Receptor and Its Ligands in Cardiovascular Diseases. [PDF]

open access: yesInt J Mol Sci
Kempiński M   +6 more
europepmc   +1 more source

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