Results 231 to 240 of about 50,860 (258)
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Evidence for a Second Desensitized State of β‐Adrenergic Receptor with Low Affinity for β‐Antagonists and Normal Reactivity towards β‐Agonists in Adipocyte Membranes Previously Exposed to β‐Antagonists

European Journal of Biochemistry, 1979
When adipocyte membranes are successively exposed to (−)‐propranolol or (±)‐alprenolo1 at 25 or 4°C, repeatedly washed and then assayed for (−)‐[3H]dihydroalprenolol binding, the apparent number of β‐adrenergic binding sites is markedly decreased. Induction of this peculiar type of receptor desensitization does not require prolonged exposure of the ...
Y, Giudicelli, D, Lacasa, B, Agli
openaire   +2 more sources

[Effect of adrenergic beta-agonist on intracellular free calcium concentration in isolated acini of the parotid gland in rats].

Comptes rendus des seances de la Societe de biologie et de ses filiales, 1996
The variations in the intracellular free calcium concentration, [Ca2+]i, have been studied in isolated acini of rat parotid gland with a fluorescent probe, fura-2. In unstimulated acini, [Ca2+]i amounted to a basal value of 180 nM. Isoproterenol used at a concentration of 200 microM, in the presence of a beta-adrenergic blocker, caused a net increase ...
A, Sezan, D, Eboué, B, Rossignol
openaire   +1 more source

Molecular orbital studies on the mechanism of drug-receptor interaction. 5. Molecular reactivity and receptor affinity of beta-agonist adrenergic drugs.

Drug design and delivery, 1989
The electrostatic molecular potential (EMP) of model compounds (isoproterenol and four of its analogs) with agonist activity on the beta-adrenergic receptor was investigated, at the SCF-MO ab initio level. A method was developed to calculate the drug-receptor interaction energy (delta E) for these compounds, and the EMP and delta E values were compared
B, Macchia, A, Martinelli
openaire   +1 more source

Dual Treatment of a Beta 3 Adrenergic Receptor Agonist and a Novel Estrogen Receptor Beta Agonist on Body Composition, Metabolism, and Glucose Tolerance in Obese Male Mice

Physiology
INTRODUCTION: Estrogen is protective against weight gain via mechanisms mediated by adipocyte-specific receptors. Specifically, estrogen receptor beta (ERb) activation is non-feminizing and increases adipocyte mitochondrial activity leading to increased energy expenditure (EE ...
John Cullen   +7 more
openaire   +1 more source

Potentiation by beta agonists of alpha adrenergically mediated contractions in the guinea-pig vas deferens

European Journal of Pharmacology, 1990
M.A. Khayyal   +3 more
openaire   +1 more source

Effectiveness and safety of the oxytocin antagonist atosiban versus beta-adrenergic agonists in the treatment of preterm labour. The Worldwide Atosiban versus Beta-agonists Study Group.

BJOG : an international journal of obstetrics and gynaecology, 2001
To compare the effectiveness and safety of the oxytocin antagonist atosiban with conventional beta-adrenergic agonist (beta-agonist) therapy in the treatment of preterm labour.Three multinational, multicentre, double-blind, randomised, controlled trials. Setting Hospitals in Australia, Canada, Czech Republic, Denmark, France, Israel, Sweden, and the UK.
openaire   +1 more source

Effects Of Rare ²2-Adrenergic Receptor Gene Variants And Long-Acting Beta Agonists On Healthcare Utilization And Corticosteroid Use In Two Multi-Ethnic Asthma Populations

B21. GENETICS OF ASTHMA, 2012
Victor E. Ortega   +10 more
openaire   +1 more source

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