Results 1 to 10 of about 222,564 (262)

ADRENERGIC RECEPTORS IN CORONARY ARTERIES* [PDF]

Annals of the New York Academy of Sciences, 1967
Peer Reviewed ; http://deepblue.lib.umich.edu/bitstream/2027.42/72463/1/j.1749-6632.1967.tb41248.x ...
David F. Bohr
openaire   +5 more sources

The β3-Adrenergic Receptor: Structure, Physiopathology of Disease, and Emerging Therapeutic Potential [PDF]

Advances in Pharmacological and Pharmaceutical Sciences
The discovery and characterization of the signal cascades of the β-adrenergic receptors have made it possible to effectively target the receptors for drug development.
Julius T. Dongdem, Axandrah E. Etornam, Solomon Beletaa, Issah Alidu, Hassan Kotey, Cletus A. Wezena   +5 more
doaj   +2 more sources

Adrenergic β2 receptor activation stimulates anti-inflammatory properties of dendritic cells in vitro. [PDF]

PLoS ONE, 2014
Vagal nerve efferent activation has been shown to ameliorate the course of many inflammatory disease states. This neuro-modulatory effect has been suggested to rest on acetylcholine receptor (AChR) activation on tissue macrophages or dendritic cells (DCs)
Laurens E Nijhuis, Brenda J Olivier, Shobit Dhawan, Francisca W Hilbers, Louis Boon, Monika C Wolkers, Janneke N Samsom, Wouter J de Jonge   +7 more
doaj   +4 more sources

β2-adrenergic receptor knockout mice exhibit A diabetic retinopathy phenotype. [PDF]

PLoS ONE, 2013
There is considerable evidence from our lab and others for a functional link between β-adrenergic receptor and insulin receptor signaling pathways in retina.
Youde Jiang, Qiuhua Zhang, Li Liu, Jie Tang, Timothy S Kern, Jena J Steinle   +5 more
doaj   +1 more source

Implication of β2-adrenergic receptor and miR-196a correlation in neurite outgrowth of LNCaP prostate cancer cells.

PLoS ONE, 2021
The β2-adrenergic receptor has been shown to be involved in neuroendocrine differentiation and to contribute to the development of aggressive prostate cancer.
Ilaria Guerriero, Håkon Ramberg, Krizia Sagini, Manuel Ramirez-Garrastacho, Kristin A Taskén, Alicia Llorente   +5 more
doaj   +1 more source

Co-Evolution of Opioid and Adrenergic Ligands and Receptors: Shared, Complementary Modules Explain Evolution of Functional Interactions and Suggest Novel Engineering Possibilities

Life, 2021
Cross-talk between opioid and adrenergic receptors is well-characterized and involves second messenger systems, the formation of receptor heterodimers, and the presence of extracellular allosteric binding regions for the complementary ligand; however ...
Robert Root-Bernstein, Beth Churchill
doaj   +1 more source

Influence of Receptor Polymorphisms on the Response to α-Adrenergic Receptor Blockers in Pheochromocytoma Patients

Biomedicines, 2022
Background: Presurgical treatment with an α-adrenergic receptor blocker is recommended to antagonize the catecholamine-induced α-adrenergic receptor mediated vasoconstriction in patients with pheochromocytoma or sympathetic paraganglioma (PPGL). There is,
Annika M. A. Berends, Mathieu S. Bolhuis, Ilja M. Nolte, Edward Buitenwerf, Thera P. Links, Henri J. L. M. Timmers, Richard A. Feelders, Elisabeth M. W. Eekhoff, Eleonora P. M. Corssmit, Peter H. Bisschop, Harm R. Haak, Ron H. N. van Schaik, Samira el Bouazzaoui, Bob Wilffert, Michiel N. Kerstens   +14 more
doaj   +1 more source

High-fat diet induces protein kinase A and G-protein receptor kinase phosphorylation of β2 -adrenergic receptor and impairs cardiac adrenergic reserve in animal hearts. [PDF]

, 2017
Key pointsPatients with diabetes show a blunted cardiac inotropic response to β-adrenergic stimulation despite normal cardiac contractile reserve. Acute insulin stimulation impairs β-adrenergically induced contractile function in isolated cardiomyocytes ...
Chiamvimonvat, Nipavan, Fu, Qin, Hu, Yuting, Kim, Sungjin, Li, Ning, Liu, Yongming, Wang, Qingtong, Xiang, Yang K, Xu, Bing   +8 more
core   +2 more sources

Genetically Encoded Biosensors Reveal PKA Hyperphosphorylation on the Myofilaments in Rabbit Heart Failure [PDF]

, 2016
RATIONALE: In heart failure, myofilament proteins display abnormal phosphorylation, which contributes to contractile dysfunction. The mechanisms underlying the dysregulation of protein phosphorylation on myofilaments is not clear.
Barbagallo, Federica, Bers, Donald, Bossuyt, Julie, Ferrier, William, Fu, Qin, Ginsburg, Kenneth S., Isidori, Andrea, Li, Minghui, Naro, Fabio, Patel, Hemal H., Reddy, Gopireddy R., Shi, Qian, Wang, Qingtong, West, Toni, Xiang, Yang K., Xu, Bing   +15 more
core   +1 more source

Sex-Related Effects of Prenatal Stress on Region-Specific Expression of Monoamine Oxidase A and β Adrenergic Receptors in Rat Hearts

Arquivos Brasileiros de Cardiologia, 2018
Background: Prenatal stress may increase risk of developing cardiovascular disorders in adulthood. The cardiotoxic effects of catecholamines are mediated via prolonged adrenergic receptor stimulation and increased oxidative stress upon their degradation ...
Tanja Jevjdovic, Tamara Dakic, Sonja Kopanja, Iva Lakic, Predrag Vujovic, Nebojsa Jasnic, Jelena Djordjevic   +6 more
doaj   +1 more source