Results 1 to 10 of about 2,589,815 (356)

Prognostic significance of beta‐adrenergic receptor expression in oesophageal adenocarcinoma [PDF]

The Journal of Pathology: Clinical Research
Expression of the β‐adrenergic receptors' family has been associated with survival outcomes in multiple different cancer types, showing their potential to act as prognostic factors.
Talita Oliveira, Swathi Sasi, James Trainor, Damian T McManus, Stephen McQuaid, Claire Lewis, Jacqueline A James, Helen G Coleman, Úna C McMenamin, Richard C Turkington   +9 more
doaj   +2 more sources

Adrenergic β2 receptor activation stimulates anti-inflammatory properties of dendritic cells in vitro. [PDF]

PLoS ONE, 2014
Vagal nerve efferent activation has been shown to ameliorate the course of many inflammatory disease states. This neuro-modulatory effect has been suggested to rest on acetylcholine receptor (AChR) activation on tissue macrophages or dendritic cells (DCs)
Laurens E Nijhuis, Brenda J Olivier, Shobit Dhawan, Francisca W Hilbers, Louis Boon, Monika C Wolkers, Janneke N Samsom, Wouter J de Jonge   +7 more
doaj   +5 more sources

β-Adrenergic receptor signaling in prostate cancer

Frontiers in Oncology, 2015
Enhanced sympathetic signaling, often associated with obesity and chronic stress, is increasingly acknowledged as a contributor to cancer aggressiveness.
Peder Rustøen Braadland, Håkon André Ramberg, Helene Hartvedt Grytli, Kristin Austlid Taskén, Kristin Austlid Taskén   +4 more
doaj   +2 more sources

Effect of β3-adrenergic receptor agonists on [18F] fluorodeoxyglucose uptake in brown adipose tissues in positron emission tomography images of elderly patients [PDF]

EJNMMI Research
Background Brown adipose tissues (BAT) are highly vascularized, mitochondria-rich tissues involved in thermogenesis. Physiological [18F]fluorodeoxyglucose ([18F]FDG) uptake in BAT can be influenced by several factors, including the use of medications ...
John Kenneth V. Gacula, Kenichiro Ogane, Kaori Fuse, Miyako Morooka Chikanishi, Kimiteru Ito   +4 more
doaj   +2 more sources

β-adrenergic receptor responsiveness in aging heart and clinical implications

Frontiers in Physiology, 2014
Elderly healthy individuals have a reduced exercise tolerance and a decreased left ventricle inotropic reserve related to increased vascular afterload, arterial-ventricular load mismatching, physical deconditioning and impaired autonomic regulation (the ...
Nicola eFerrara, Nicola eFerrara, Klara eKomici, Graziamaria eCorbi, Gennaro ePagano, Giuseppe eFurgi, Carlo eRengo, Carlo eRengo, Grazia Daniela eFemminella, Dario eLeosco, Domenico eBonaduce   +10 more
doaj   +2 more sources

The β3-Adrenergic Receptor: Structure, Physiopathology of Disease, and Emerging Therapeutic Potential [PDF]

Advances in Pharmacological and Pharmaceutical Sciences
The discovery and characterization of the signal cascades of the β-adrenergic receptors have made it possible to effectively target the receptors for drug development.
Julius T. Dongdem, Axandrah E. Etornam, Solomon Beletaa, Issah Alidu, Hassan Kotey, Cletus A. Wezena   +5 more
doaj   +2 more sources

Constant-pH Simulation of the Human β₂ Adrenergic Receptor Inactivation. [PDF]

J Chem Inf Model
Ballabio F, Capelli R.
europepmc   +2 more sources

β2-adrenergic receptor knockout mice exhibit A diabetic retinopathy phenotype. [PDF]

PLoS ONE, 2013
There is considerable evidence from our lab and others for a functional link between β-adrenergic receptor and insulin receptor signaling pathways in retina.
Youde Jiang, Qiuhua Zhang, Li Liu, Jie Tang, Timothy S Kern, Jena J Steinle   +5 more
doaj   +1 more source

Implication of β2-adrenergic receptor and miR-196a correlation in neurite outgrowth of LNCaP prostate cancer cells.

PLoS ONE, 2021
The β2-adrenergic receptor has been shown to be involved in neuroendocrine differentiation and to contribute to the development of aggressive prostate cancer.
Ilaria Guerriero, Håkon Ramberg, Krizia Sagini, Manuel Ramirez-Garrastacho, Kristin A Taskén, Alicia Llorente   +5 more
doaj   +1 more source

Co-Evolution of Opioid and Adrenergic Ligands and Receptors: Shared, Complementary Modules Explain Evolution of Functional Interactions and Suggest Novel Engineering Possibilities

Life, 2021
Cross-talk between opioid and adrenergic receptors is well-characterized and involves second messenger systems, the formation of receptor heterodimers, and the presence of extracellular allosteric binding regions for the complementary ligand; however ...
Robert Root-Bernstein, Beth Churchill
doaj   +1 more source