Methylation Status of Vitamin D Receptor Gene Promoter in Benign and Malignant Adrenal Tumors [PDF]
International Journal of Endocrinology, 2015 We previously showed a decreased expression of vitamin D receptor (VDR) mRNA/protein in a small group of adrenocortical carcinoma (ACC) tissues, suggesting the loss of a protective role of VDR against malignant cell growth in this cancer type ...
Catia Pilon +7 more
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Emergence of Ectopic Adrenal Tissues-What are the Probable Mechanisms?
JCRPE, 2022 Ectopic adrenal tissue, defined as the formation of adrenal tissue in an abnormal anatomical location, is not a rare entity and may have clinical significance. Even though the mechanism for their emergence has not been fully understood, numerous cases of
Gürkan Tarçın, Oya Ercan
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Adrenocortical neoplasms in children: Treatment and outcomes
Journal of Indian Association of Pediatric Surgeons, 2022 Background: Adrenocortical tumors are rare tumors in children with a paucity of outcome data, especially in a resource-challenged setting. Materials and Methods: A retrospective study was conducted to evaluate the presentation, management, and outcomes ...
Vishesh Jain +9 more
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Current Status and Future Targeted Therapy in Adrenocortical Cancer
Frontiers in Endocrinology, 2021 Adrenocortical carcinoma (ACC) is a rare malignancy with a poor prognosis. The current treatment standards include complete surgical resection for localized resectable disease and systemic therapy with mitotane alone or in combination with etoposide ...
George Alyateem, Naris Nilubol
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Silencing mutated β-catenin inhibits cell proliferation and stimulates apoptosis in the adrenocortical cancer cell line H295R [PDF]
, 2013 Adrenocortical carcinoma (ACC) is a rare and highly aggressive endocrine neoplasm, with limited therapeutic options. Activating β-catenin somatic mutations are found in ACC and have been associated with a poor clinical outcome. In fact, activation of the
Bertherat, Jérôme +11 more
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Large adrenocortical adenoma with malignant features on imaging: A case report
Urology Case Reports, 2022 Large adrenocortical adenomas have rarely been reported. We describe a case of a 26-year-old man who underwent an adrenalectomy for a large adrenocortical adenoma (8.6 × 7.7 cm).
Shin Koike +5 more
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A rare presentation of adrenal adenoma in infancy: isolated Cushing`s syndrome
The Turkish Journal of Pediatrics, 2020 Adrenocortical tumors are rare in children. Most of these tumors present with endocrinological manifestations, majority of which with virilizing features alone or in combination with over production of other adrenal hormones.
Oğuzhan Şal +2 more
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Prenatal presentation of an adrenocortical tumor
Cancer Reports, 2022 Background Prenatally identified suprarenal masses are most often found to be adrenal hemorrhage. The most common tumor in this situation is neuroblastoma. Case Presentation We report the case of a rare adrenocortical tumor found prenatally on ultrasound.
Jeffrey H. Schwartz, Erlyn Smith
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Ectopic adrenocortical adenoma in the renal hilum mimicking a renal cell carcinoma
Radiology Case Reports, 2022 Ectopic adrenocortical tissue can arise along the path of embryonic migration, such as the celiac axis, broad ligament, adnexa of the testis, and spermatic cord.
Masashi Endo, MD +7 more
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KIAA0101 is overexpressed, and promotes growth and invasion in adrenal cancer. [PDF]
PLoS ONE, 2011 BACKGROUND:KIAA0101 is a proliferating cell nuclear antigen-associated factor that is overexpressed in some human malignancies. Adrenocortical neoplasm is one of the most common human neoplasms for which the molecular causes are poorly understood ...
Meenu Jain +3 more
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