Results 41 to 50 of about 8,531 (170)
Whole transcriptome profiling is a promising technique in adrenal studies; however, whole transcriptome profiling of adrenal disease using formalin-fixed paraffin-embedded (FFPE) samples has to be further explored.
Norifusa Iwahashi +12 more
doaj +1 more source
CYP11B2 immunohistochemistry identifies aldosterone‐producing nodules and enables objective subtyping using the B2 ratio (B2R), defined as the size ratio between the largest and second‐largest CYP11B2‐positive nodules. A B2R ≥8.1 indicates classical histology with a dominant lesion and high likelihood of cure, whereas B2R <8.1 reflects non‐classical ...
Adam Stenman +3 more
wiley +1 more source
Immunohistochemical analysis of ghrelin expression in various types of adrenal tumors
INTRODUCTION: Ghrelin, originally isolated from the endocrine cells of the gastric mucosa, is also expressed in many peripheral tissues, including normal adrenals and adrenocortical tumors.
Hanna Komarowska +6 more
doaj +1 more source
Expression of Topoisomerase II Alpha in Canine Colorectal Polyps, Adenomas and Adenocarcinomas
ABSTRACT With the development and increased accessibility of diagnostic methods in veterinary medicine, the possibilities for early detection of proliferative lesions in the canine large intestine have expanded over the past decade. Since in human medicine, topoisomerase II alpha (Topo IIα) is considered a prognostic and predictive marker in various ...
Joanna Fiedorowicz +3 more
wiley +1 more source
Pheochromocytoma and Adrenocortical Adenoma in the Same Gland
A right adrenal tumor was found incidentally during abdominal computed tomography exam in a 51-year-old female patient, who had had diabetes and hypertension for more than 10 years. The computed tomography scan was arranged for possible pancreatic lesion by a neurologist. Norepinephrine level was high in the plasma and urine.
Hwang, Wei-Ren +5 more
openaire +2 more sources
Abstract Objective To describe the perioperative and long‐term outcomes of dogs with massive hepatocellular carcinoma (HCC) in the right hepatic division causing compression or involvement of the caudal vena cava (CVC) treated with right divisional hepatectomy using temporary caval occlusion (TCO). Study design Retrospective case series.
Kumiko Ishigaki +6 more
wiley +1 more source
Cellular Senescence in Adrenocortical Biology and Its Disorders
Cellular senescence is considered a physiological process along with aging and has recently been reported to be involved in the pathogenesis of many age-related disorders. Cellular senescence was first found in human fibroblasts and gradually explored in
Xin Gao +5 more
doaj +1 more source
ABSTRACT Adrenocortical tumors are infrequent neoplasms, ranging from benign adenomas to aggressive carcinomas. They usually have an unspecific clinical presentation, thus being a challenge in diagnosis and treatment. The following case report discusses the management of a large, non‐functional adrenocortical tumor with histologically aggressive ...
Jawad Khan +8 more
wiley +1 more source
A Ten Year Overview of Adrenal Vein Sampling in Croatia: Insights and Outcomes
ABSTRACT Background Adrenal vein sampling (AVS) is the gold standard for subtype differentiation in primary aldosteronism (PA), yet it remains technically demanding and resource intensive. However, data on long‐term performance, learning curves, and concordance with imaging in real‐world clinical practice are limited.
Karin Zibar Tomsic +4 more
wiley +1 more source
New evidences on the regulation of SF-1 expression by POD1/TCF21 in adrenocortical tumor cells
OBJECTIVES: Transcription Factor 21 represses steroidogenic factor 1, a nuclear receptor required for gonadal development, sex determination and the regulation of adrenogonadal steroidogenesis.
Monica Malheiros França +3 more
doaj +1 more source

