Results 41 to 50 of about 8,080 (165)

FOXA1 is a highly sensitive diagnostic marker for prostate cancer including small cell carcinoma of the prostate

Histopathology, EarlyView.
FOXA1 is a highly sensitive diagnostic marker for prostate cancer. Besides prostatic adenocarcinoma, it is also expressed in 57%–80% of metastatic or primary prostatic small cell carcinomas, which lose traditional prostatic markers including NKX3.1. Although it is less specific than NKX3.1, it can serve as a valuable adjunct for confirming prostatic ...
Jianping Zhao, Jun Yao, Hossein Hosseini, Ezra Baraban, Ruihe Lin, Charles C. Guo, Lei Huo, Wei Lu, Khaja Khan, Shufang Wang, Luisa Maren Solis Soto, Qingqing Ding   +11 more
wiley   +1 more source

Exacerbation of Cushing’s syndrome during pregnancy: stimulation of a cortisol-secreting adrenocortical adenoma by ACTH originating from the foeto-placental unit

Endocrinology, Diabetes & Metabolism Case Reports, 2019
A 29-year-old G4A3 woman presented at 25 weeks of pregnancy with progressive signs of Cushing’s syndrome (CS), gestational diabetes requiring insulin and hypertension.
Matthieu St-Jean, Jessica MacKenzie-Feder, Isabelle Bourdeau, André Lacroix   +3 more
doaj   +1 more source

Outcomes and opportunities: evaluating an unselected cohort of patients with adrenal incidentaloma at a tertiary hospital in New Zealand

Internal Medicine Journal, EarlyView.
Abstract Background The prevalence of adrenal incidentalomas is increasing, along with the incidence of functional or malignant lesions. This study assessed how imaging of adrenal incidentalomas at a tertiary hospital in Auckland, New Zealand, without a dedicated adrenal incidentaloma service, conformed to the American College of Radiology (ACR ...
Anthony Benfell, Liam Quinlan, Kunj Joshi, Tej Joshi, Shekhar Sehgal   +4 more
wiley   +1 more source

Cellular Senescence in Adrenocortical Biology and Its Disorders

Cells, 2021
Cellular senescence is considered a physiological process along with aging and has recently been reported to be involved in the pathogenesis of many age-related disorders. Cellular senescence was first found in human fibroblasts and gradually explored in
Xin Gao, Faping Li, Bin Liu, Yuxiong Wang, Yishu Wang, Honglan Zhou   +5 more
doaj   +1 more source

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

Advanced Science, Volume 13, Issue 32, 9 June 2026.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun, Changying Jing, Martina Tetti, Siyuan Gong, Jia Wei, Yingxian Pang, Martin Reincke, Tracy Ann Williams   +7 more
wiley   +1 more source

The aging paradox of Cushing's syndrome: Stress without clear senescence?

Journal of Neuroendocrinology, Volume 38, Issue 6, June 2026.
Abstract Cushing's syndrome (CS), characterized by chronic endogenous hypercortisolism and disruption of the normal circadian cortisol rhythm, represents a unique human model for investigating the interplay between stress endocrinology and biological aging.
Israel Nunes Silveira, Alexandro Guterres   +1 more
wiley   +1 more source

Pheochromocytoma and Adrenocortical Adenoma in the Same Gland

Journal of the Chinese Medical Association, 2007
A right adrenal tumor was found incidentally during abdominal computed tomography exam in a 51-year-old female patient, who had had diabetes and hypertension for more than 10 years. The computed tomography scan was arranged for possible pancreatic lesion by a neurologist. Norepinephrine level was high in the plasma and urine.
Hwang, Wei-Ren, Ma, Wen-Ya, Tso, An-Li, Pan, Chin-Chen, Chang, Yen-Hwa, Lin, Hong-Da   +5 more
openaire   +2 more sources

A Multi‐Institutional Retrospective Study of 21 Dogs Having Undergone Hypofractionated Radiotherapy for Adrenal Tumours (2017–2024)

Veterinary and Comparative Oncology, Volume 24, Issue 2, Page 229-239, June 2026.
ABSTRACT Radiation therapy (RT) has emerged as a promising non‐surgical approach for treating canine adrenal tumours. This multi‐institutional, retrospective study describes clinical outcomes for 21 dogs having been prescribed a course of hypofractionated image‐guided intensity‐modulated RT (IMRT) entailing delivery of 25–35 Gy total in 5 fractions ...
Yen‐Hao Erik Lai, Michael S. Kent, Michael W. Nolan, Dah‐Renn Fu, Jayme S. Looper   +4 more
wiley   +1 more source

New evidences on the regulation of SF-1 expression by POD1/TCF21 in adrenocortical tumor cells

Clinics
OBJECTIVES: Transcription Factor 21 represses steroidogenic factor 1, a nuclear receptor required for gonadal development, sex determination and the regulation of adrenogonadal steroidogenesis.
Monica Malheiros França, Antonio M. Lerario, Maria Candida B.V. Fragoso, Claudimara Ferini Pacicco Lotfi   +3 more
doaj   +1 more source

Adrenocortical Adenocarcinoma in a Syrian Golden Hamster (Mesocricetus auratus) With Suspected Hyperadrenocorticism

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
A 2‐year‐old female golden hamster presented with non‐pruritic alopecia of the hindquarters. Diagnostic imaging and cytological evaluation revealed a unilateral adrenal mass consistent with an adrenocortical tumour, while biochemical analyses suggested corticosteroid secretion.
Mathilde Firmin Billaux, Sabrina Vieu, Antoine Lecomte, Marie Cuvelier, Marine Rohel, Jérôme Abadie, Nicolas Soetart   +6 more
wiley   +1 more source