Results 81 to 90 of about 18,670 (220)
Abstract The study investigated whether bicycle compared with car commuting, over relatively small distances, has positive effects on physiological variables, cardiometabolic fitness and CO2 output in the atmosphere. Bike Commuters (11 M, 15 F; age [median value (interquartile range)] 51.5 (38.3–56.8) years; body mass index [BMI] 22.8 (21.0–24.1) kg m ...
Caterina Ursella +11 more
wiley +1 more source
Expression of adrenomedullin and proadrenomedullin N-terminal 20 peptide in human and rat prostate [PDF]
Adrenomedullin (AM) and proadrenomedullin N-terminal 20 peptide (PAMP) are two recently discovered hypotensive peptides translated from the same message transcript (preproAM mRNA).
Calvo, A. (Alfonso) +5 more
core +1 more source
Abstract Endothelial dysfunction drives obesity‐related complications. Doppler ultrasound measurement of blood flow during 1‐min passive leg movements (PLM) is a valuable non‐invasive tool for assessing endothelial function and nitric oxide (NO)‐mediated vasodilation.
Lucrezia Zuccarelli +13 more
wiley +1 more source
The Role of Adrenomedullin in the Renal NADPH Oxidase and (Pro)renin in Diabetic Mice
Adrenomedullin has an antioxidative action and protects organs in various diseases. To clarify the role of adrenomedullin in diabetic nephropathy, we investigated the NADPH oxidase expression, renin-secreting granular cell (GC) hyperplasia, and ...
Michio Hayashi +3 more
doaj +1 more source
Fighting obesity by targeting factors regulating beige adipocytes. [PDF]
Purpose of reviewThe current review provides an update on secreted factors and mechanisms that promote a thermogenic program in beige adipocytes, and their potential roles as therapeutic targets to fight obesity.Recent findingsWe outline recent studies ...
Koliwad, Suneil K +2 more
core +1 more source
Pro-adrenomedullin, pro-endothelin-1, procalcitonin, C-reactive protein and mortality risk in critically ill children: a prospective study [PDF]
INTRODUCTION: We tested the hypothesis that higher mid-regional pro-adrenomedullin (MR-proADM), carboxy-terminal pro-endothelin-1 (CT-proET-1), procalcitonin (PCT) and C-reactive protein (CRP) plasma concentrations would be associated with increased ...
Botrán, Marta +7 more
core +2 more sources
Single‐nucleus multi‐omics profiling of sinonasal squamous cell carcinoma unveils a hypoxia‐driven angiogenic axis. A specific hypoxic tumor subpopulation orchestrates endothelial tip cell differentiation via epigenetically regulated ADM and VEGFA secretion.
Chaelin You +12 more
wiley +1 more source
Pro-adrenomedullin to predict severity and outcome in community-acquired pneumonia [ISRCTN04176397] [PDF]
INTRODUCTION: Pro-adrenomedullin (proADM) is helpful for individual risk assessment and outcome prediction in sepsis. A major cause of sepsis is community-acquired pneumonia (CAP).
Mirjam Christ-Crain +9 more
core +1 more source
Tumor‐associated macrophages are the most abundant immune cells in the tumor microenvironment, driving malignant progression and treatment resistance. This review summarizes the protumor mechanisms of TAMs (including phagocytosis modulation, metabolic reprogramming, exosomal communication, and immune interactions), evaluates three major strategies ...
Wurihan Bao +8 more
wiley +1 more source

