Results 61 to 70 of about 689,743 (389)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

透過社會運動學習：萬華社區大學講師陳情行動歷程之框架理論分析 Learning Through Social Movement: A Study of the Application of Framing Theory in a Petition Process Initiated by Instructors of Wanhua Community College

臺灣教育社會學研究, 2013
本研究採質性研究方法，順著萬華社區大學（後稱社大）講師陳情行動進程，釐清講師們如何透過框架理論操作持續賦予教育局負面評鑑結果另類新意，並藉由擬訂因應策略喚起參與動機，抗議教育局評鑑不公，爭取程序正義。研究發現，社大講師參與陳情行動的主因並非公共理由，而是教育局的污名化評鑑結果與其正向認同與情感落差過大；加上教育局撤銷或接管社大耳語不斷，他校支持者又將社大運作機制結構性問題搬上檯面，更讓講師認定此事出於教育局不公，進而激發其不滿情緒和參與動力。此外，本研究也發現陳情行動的參與 ...
徐敏雄 Min-Hsiung Hsu
doaj   +1 more source

Adult and Continuing Education in Norway

, 2016
The European arena of lifelong learning offers rich country-specific portfolios of historical trajectories, policy frameworks and practical evidence of adult and continuing education. This book provides an introduction to the case of Norway and outlines the key features of the Norwegian system alongside issues such as political and legal agendas ...
openaire   +5 more sources

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

The Continuing Nursing Education and Adult Education Movements in the United States

Nursing Forum, 1981
Irene Schor
openaire   +4 more sources

Explaining Change and Rethinking Dirty Words: FCC v. Fox Television Stations, Inc. [PDF]

, 2008
This report presents the results from a comparative study of the qualification of adult educators in the Nordic-Baltic region. The study involved Denmark, Estonia and Sweden.
Andersson, Per, Gross, Marin, Jõgi, Larissa, Köpsén, Susanne, Larson, Anne, Milana (ed.), Marcella   +5 more
core   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Message Sidedness in Health Claims: Roles of Mood State, Product Involvement, and Self-Rated Health Status

Frontiers in Nutrition, 2021
Most of the previous studies with respect to message sidedness mainly focus on the effect of message sidedness in advertising on behavior of consumers and it is unknown how consumers respond to different message sidedness when a one-sided or two-sided ...
Hung-Chou Lin, Shih-Tse Wang
doaj   +1 more source

Masters' courses in the education of adults in the UK [PDF]

, 2005
This is a paper from the Academic Papers Online series from ESCalate, written by John Field, Richard Dockrell, Peter Gray in 2005. Universities provide a range of advanced qualifications for professionals who support adult learners.
Dockrell, Richard, Field, John, Gray, Peter   +2 more
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