Results 71 to 80 of about 15,097 (214)

Granulosa cell tumor of the ovary: a clinicopathological study of six cases

Journal of Pathology of Nepal, 2011
Background: Ovarian granulosa cell tumors are rare malignant neoplasms that originate from the sexcord stromal cells of the ovary. The study aims to collate data of all granulosa cell tumors diagnosed in Tribhuvan University Teaching Hospital over the ...
RC Adhikari, A Jha, G Shayami
doaj   +1 more source

Wnt5a Signaling in Normal and Cancer Stem Cells. [PDF]

, 2017
Wnt5a is involved in activating several noncanonical Wnt signaling pathways, which can inhibit or activate canonical Wnt/β-catenin signaling pathway in a receptor context-dependent manner.
Kipps, Thomas J, Zhang, Suping, Zhou, Yan   +2 more
core   +2 more sources

The mitochondrial DNA copy number and ovary‐related reproductive disorders: A bidirectional two‐sample Mendelian randomization study

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 112-120, April 2025.
Abstract Objective In the present study, a bidirectional two‐sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA‐CN) and ovary‐related reproductive disorders (ORRDs), including ovarian dysfunction, ovarian cyst, polycystic ovary syndrome (PCOS), premature ovarian ...
Ke Peng, Xiao Han, Congquan Wu, Qiaowen Lu, Shujun Gao   +4 more
wiley   +1 more source

Is it time to abandon staging surgery and prolonged follow-up in patients with primary adult-type granulosa cell tumor?

Journal of Ovarian Research
Background As current literature does not provide sufficient data to support clear guidelines in patients with a rare adult-type granulosa cell tumor, we aim to investigate: (1) whether additional staging surgery following primary surgical treatment is ...
Geertruid J. Brink, Jolijn W. Groeneweg, Ariane A. Sickinghe, Hans W. Nijman, Luc R.C.W. van Lonkhuijzen, Christianne A. R. Lok, Jurgen M. J. Piek, Eva Maria Roes, Cornelis D. de Kroon, Ward Hofhuis, Geertruida N. Jonges, Eelke H. Gort, Petronella O. Witteveen, Ronald P. Zweemer   +13 more
doaj   +1 more source

Follicle stimulating hormone modulates ovarian stem cells through alternately spliced receptor variant FSH-R3 [PDF]

, 2013
BACKGROUND: We have earlier reported that follicle stimulating hormone (FSH) modulates ovarian stem cells which include pluripotent, very small embryonic-like stem cells (VSELs) and their immediate descendants ‘progenitors’ termed ovarian germ stem cells
Deepa Bhartiya, Hiren Patel, Mithun Bhatt, Pranesh Gunjal, Seema Parte, Snehal Yedurkar   +5 more
core   +1 more source

Combination of transvaginal ultrasound with cervical cancer screening contributes to early detection of ovarian cancer: Clinical trial

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Early detection of ovarian cancer at stage I is important to improve patients‘ prognosis. The goal of this study was to examine if transvaginal ultrasound (TVU) performed at the same time as cervical cancer screening can facilitate early detection of ovarian cancer.
Hiromasa Fujita, Kazuhira Okamoto, Hidenori Kato, Hidemichi Watari, Nobuyoshi Ozawa, Mitsuaki Suzuki   +5 more
wiley   +1 more source

Juvenile Granulosa Cell Tumors of the Testis: A Clinicopathologic Study of 70 Cases with Emphasis on Its Wide Morphologic Spectrum [PDF]

, 2015
The clinical and pathologic features of 70 juvenile granulosa cell tumors (JGCTs) of the testis are presented. The patients were from 30 weeks gestational age to 10 years old; 60 of 67 (90%) whose ages are known to us were 6 months old or younger.
Cornejo, Kristine M., Kao, Chia-Sui, Ulbright, Thomas M., Young, Robert H.   +3 more
core   +1 more source

Adult Type Granulosa Cell Tumor of the Testis

Korean Journal of Urology, 2008
Dong Jun Kim, Dong Woo Song, Sang Yeop Yi, Woon Yong Yun, Tae Yung Jeong From the Departments of Urology and Pathology, College of Medicine, Kwandong University, Goyang, Korea Testicular granulosa cell tumor (GCT) is a rare neoplasm. We report here on an incidentally discovered testicular granulosa cell tumor in a 36-year-old man.
Dong Jun Kim, Dong Woo Song, Sang Yeop Yi, Woon Yong Yun, Tae Yung Jeong   +4 more
openaire   +1 more source

Chinese pan‐cancer patient genomic characteristics: A comprehensive analysis based on the National Cancer Center–Clinical Diagnostics Knowledgebase real‐world clinical sequencing cohort

Interdisciplinary Medicine, EarlyView.
We assembled National Cancer Center–Clinical Diagnostics Knowledgebase, a clinical genomic knowledgebase of 6935 tumors with matched normal samples, revealing key somatic alterations and actionable variants (70.2% of the cohort). Enrichment of certain different gene mutations was observed between Chinese and American populations, along with a strong ...
Hongrui Li, Shun Wang, Guowei Zhao, Jiangtao Li, Xin Li, Bingning Wang, Yi Zhang, Mengfei Yao, Lei Guo, Jianming Ying, Wenbin Li   +10 more
wiley   +1 more source

Characteristics and outcome of recurrence in molecularly defined adult-type ovarian granulosa cell tumors [PDF]

, 2016
Objective. Adult-type ovarian granulosa cell tumors (AGCTs) have an unpredictable tendency to relapse. In a carefully validated patient cohort, we evaluated the prognostic factors related to AGCT recurrence. Methods.
Bryk, Saara Susanna, Butzow, Ralf, Färkkilä, Anniina, Heikinheimo, Markku, Johanna, Tapper, Leminen, Arto, Riska, Annika, Unkila-Kallio, Leila   +7 more
core   +1 more source