Results 111 to 120 of about 7,349,585 (245)
Frontiers in EndocrinologyIntroductionAdult growth hormone deficiency (AGHD) is associated with a high prevalence of metabolic syndrome (MS), which contributes to the unfavorable cardiovascular risk profile in these patients.
Balázs Ratku +18 more
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, 2017 Objective: Ocular function is fundamental for environmental adaptation and survival capacity. Growth factors are necessary for a mature eyeball, needed for adequate vision.
Oliveira-Santos, A. A. +12 more
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FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
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In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
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FEBS Open Bio, EarlyView.The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
Growth hormone deficiency in children.
, 2014 Growth hormone (GH) deficiency may be of congenital origin and may present with typical clinical signs and symptoms very early in postnatal life, but may also present later during childhood with growth deceleration. In a short-statured child suspected of
Juul, Anders +2 more
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Cogntive changes during growth hormone replacement in adult men
, 1998 The present study evaluates the effects of 2 years of growth hormone (GH) replacement therapy on psychological well-being and cognitive performance in adults with childhood-onset growth hormone deficiency (CO- GHD). A total of 48 GHD adult men (mean age:
de Boer, H. +5 more
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FEBS Open Bio, EarlyView.During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa +4 more
wiley +1 more source
[Growth hormone deficiency in adults].
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1997 Growth hormone (GH) has been in clinical use for almost 40 years to promote linear growth in growth hormone deficient children. Treatment has usually been stopped after the epiphyseal plates have fused or when the person reaches a proper height. Previously, GH replacement therapy in adults was not deemed clinically indicated. GH-deficiency in adults is
T R, Meling, E S, Nylén
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Potential impacts of adult growth hormone deficiency: a population-based study in England
BMJ OpenObjectives To investigate the potential long-term impacts of adult growth hormone deficiency (GHD).Design Observational, retrospective matched cohort.Setting UK Clinical Practice Research Datalink (CPRD) Aurum database of primary care records with ...
Marzieh Araghi +4 more
doaj +1 more source