Results 131 to 140 of about 7,043,555 (280)

Isolated growth hormone deficiency type 2: from gene to therapy

, 2012
Isolated growth hormone deficiency type-2 (IGHD-2), the autosomal-dominant form of GH deficiency, is mainly caused by specific splicing mutations in the human growth hormone (hGH) gene (GH-1).
Vibor Pektovic, Lochmatter, Didier, Maria Consolata Miletta, Didier Lochmatter, Pektovic, Vibor, Primus-E. Mullis, Miletta, Maria Consolata, Mullis, Primus-E   +7 more
core   +1 more source

Intelligent Orthopedics: Machine Learning in Diagnosis of Bone Disease, Implants, and Bone Health Monitoring

Advanced Healthcare Materials, EarlyView.
Efficient recovery from traumatic or degenerative diseases is a great challenge, even after all the advancements in bone and cartilage regeneration. Machine learning (ML) algorithms have presented opportunities to enhance these aspects by accurately analyzing imaging data.
Maryam Kamaei, Hesam Mohammadi, Shamim Golafshan, Mojtaba Alehosseini, Mahsa Mohammadzadeh, Atefeh Golshirazi, Nasim Golafshan, Tatiane Eufrásio‐da‐Silva, Alireza Dolatshahi‐Pirouz, Gorka Orive   +9 more
wiley   +1 more source

2‐Deoxyglucose Dendrimer‐Enabled Niclosamide Delivery to FRβ‐Expressing Macrophages Alleviates Endometriosis Progression and Associated Hyperalgesia

Advanced Healthcare Materials, EarlyView.
A folic acid (FA)‐conjugated 2‐deoxyglucose dendrimer selectively targets FRβ+ macrophages in endometriotic lesions, enabling precise intracellular delivery of niclosamide. This nonhormonal nanomedicine enhances drug solubility, provides controlled intracellular release, suppresses lesion growth, reduces inflammation and pain, and establishes FRβ ...
Anubhav Dhull, Mingxin Shi, Madeleine E. Harvey, Taylor M. Page, Rishi Sharma, Kenneth John Goody, Aqib Iqbal Dar, Nash S. Moawad, Vijay Kumar Sirohi, Paul S. Cooke, Kanako Hayashi, Anjali Sharma   +11 more
wiley   +1 more source

Childhood-onset growth hormone deficiency and the transition to adulthood: current perspective

Therapeutics and Clinical Risk Management, 2018
M Ahmid, SF Ahmed, MG Shaikh Development Endocrinology Research Group, School of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow, UK Abstract: Childhood-onset growth hormone deficiency (CO-GHD) is an endocrine condition associated with ...
Ahmid M, Ahmed SF, Shaikh MG
doaj  

Investigation of the metabolic and endocrinological differences between daily and weekly growth hormone replacement therapy, somapacitan, in patients with adult growth hormone deficiency: A real-world pilot study. [PDF]

Medicine (Baltimore), 2023
Abe I, Takeshita K, Nagata M, Fujita Y, Ochi K, Koga M, Kudo T, Shimada H, Abe M, Mukoubara S, Kobayashi K.   +10 more
europepmc   +1 more source

Optical Detection of Cellular Signals at Material Interfaces

Advanced Healthcare Materials, EarlyView.
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren, Jitong Ren, Zixin Zhang, Koney Eungkon Kim, Francis L. Hong, Yuecheng Peter Zhou   +5 more
wiley   +1 more source

Effects of 18 Months of Growth Hormone Replacement Therapy on Bone Mineral Density in Patients with Adult Growth Hormone Deficiency: A Retrospective Study. [PDF]

Int J Endocrinol, 2023
Shen YY, Ma JN, Ren ZY, Liu J, Zhou XY, Xie XR, Ren W.   +6 more
europepmc   +1 more source

“Smelltronics”—From Gas to Smell Sensing

Advanced Materials, EarlyView.
The emerging field of smelltronics, encompassing sensing technologies for complex volatile organic compounds, holds significant potential for extracting valuable chemical information. It facilitates the noninvasive, real‐time monitoring of humans, food, and the environment.
Takeshi Ono, Tsunaki Takahashi, Jiangyang Liu, Haruka Honda, Zeng Jing, Wataru Tanaka, Takuro Hosomi, Takeshi Yanagida   +7 more
wiley   +1 more source

Behavioral Therapy Ameliorates Severe Obesity With Low Levels of Plasma GH and IGF‐1: A Case Report

Clinical Case Reports
We encountered a patient with a body mass index of 50.7 kg/m2. Behavioral therapy was effective for preventing progression of health disturbance in this case.
Go Yoshimichi
doaj   +1 more source

Effects of adult growth hormone deficiency and replacement therapy on the cardiometabolic risk profile. [PDF]

Pituitary, 2022
Ratku B, Sebestyén V, Erdei A, Nagy EV, Szabó Z, Somodi S.   +5 more
europepmc   +1 more source