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Natural variations of adult neurogenesis and anxiety predict hierarchical status of inbred mice
Grieco F, Balla A, Larrieu T, Toni N.
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Platelet-derived LPA16:0 inhibits adult neurogenesis and stress resilience in anxiety disorder
Larrieu T +15 more
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Abstract Adult neurogenesis—the development of new neurons under the conditions of the adult brain—is an exception, not the rule, but we know today that the new neurons contribute to key brain functions. This particularly applies to neurogenesis in the hippocampus of adult mammals, including rodents and humans, where adult neurogenesis ...
Matthew Shtrahman +3 more
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Matthew Shtrahman +3 more
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Perspectives on adult neurogenesis
European Journal of Neuroscience, 2011New neurons are generated throughout life. This discovery has challenged firmly held concepts about the structural plasticity and regenerative capacity of the mammalian brain. In this special issue of the EJN, leaders in the field summarize and review recent advances aiming to understand the molecular mechanisms underlying adult neurogenesis and the ...
Knobloch Marlen, Jessberger Sebastian
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NeuroReport, 1996
This report describes neurogenesis in the adult human olfactory epithelium in vitro. Olfactory epithelium was collected at autopsy and by biopsy, and grown in serum-free medium. Basic fibroblast growth factor induced the differentiation of bipolar cells which were immunopositive for several neuronal proteins but not glial proteins.
Murrell, Wayne +6 more
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This report describes neurogenesis in the adult human olfactory epithelium in vitro. Olfactory epithelium was collected at autopsy and by biopsy, and grown in serum-free medium. Basic fibroblast growth factor induced the differentiation of bipolar cells which were immunopositive for several neuronal proteins but not glial proteins.
Murrell, Wayne +6 more
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2006
Adult neurogenesis is the generation of new neurons in the adult brain. Adult neurogenesis is an exception, as the brain of mammals is non-neurogenic. Rodents and primates have two neurogenic zones, the hippocampus and the olfactory bulb. Lower vertebrates often have many more sites of adult neurogenesis. In the peripheral nervous system, there is high
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Adult neurogenesis is the generation of new neurons in the adult brain. Adult neurogenesis is an exception, as the brain of mammals is non-neurogenic. Rodents and primates have two neurogenic zones, the hippocampus and the olfactory bulb. Lower vertebrates often have many more sites of adult neurogenesis. In the peripheral nervous system, there is high
openaire +3 more sources
Adult neurogenesis in Alzheimer's disease
Hippocampus, 2023AbstractAlzheimer's disease (AD) is the most common form of age‐related dementia, characterized by progressive memory loss and cognitive disturbances. The hippocampus, where adult hippocampal neurogenesis (AHN), a relatively novel form of brain plasticity that refers to the birth of new neurons, occurs, is one of the first brain regions to be affected ...
Se Hoon Choi, Rudolph E. Tanzi
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Signaling in Adult Neurogenesis
Annual Review of Cell and Developmental Biology, 2009The identification of neural stem cells (NSCs) and their contribution to continuous neurogenesis has shown that the hippocampus and olfactory bulb are plastic. Brain plasticity, achieved at the level of cell genesis, has an essential role in the maintenance of brain homeostasis.
Hoonkyo, Suh, Wei, Deng, Fred H, Gage
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Hippocampus, 2006
AbstractStress hormones have potent growth‐inhibiting effects on a variety of peripheral tissues. Consistent with this general function, stress has been shown to inhibit cell proliferation and, ultimately, neurogenesis in the hippocampus. This effect appears to be common across mammalian species, life stages, and most types of stressors.
Christian, Mirescu, Elizabeth, Gould
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AbstractStress hormones have potent growth‐inhibiting effects on a variety of peripheral tissues. Consistent with this general function, stress has been shown to inhibit cell proliferation and, ultimately, neurogenesis in the hippocampus. This effect appears to be common across mammalian species, life stages, and most types of stressors.
Christian, Mirescu, Elizabeth, Gould
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