Results 181 to 190 of about 94,238 (337)

A Lavandula angustifolia flower extract and dipeptide‐4 blend modulates oxidative, glycative, autophagic and circadian pathways in human skin models

open access: yesInternational Journal of Cosmetic Science, EarlyView.
The blend enhanced antioxidation, anti‐glycation, autophagy and circadian regulation in cell and skin models. Key markers included mitochondrial ROS, γ‐H2AX, AGEs, ATP, melatonin, LC3 and SOD. Significant improvements were visualized via fluorescence and quantified with statistical markers.
Lina Wang   +4 more
wiley   +1 more source

The Effect of Diabetes on Outcomes of Non‐Surgical Periodontal Therapy: A Systematic Review With a Meta‐Analysis and Trial Sequential Analysis

open access: yesInternational Journal of Dental Hygiene, EarlyView.
ABSTRACT Objective The aim of this systematic review was to critically assess and synthesise the current scientific evidence of the potential impact of diabetes mellitus (DM) on treatment outcomes in periodontitis patients following NSPT, incorporating recent advancements in meta‐analytical techniques.
L. P. M. Weijdijk   +6 more
wiley   +1 more source

Linderalactone mitigates diabetic renal injury by inhibiting macrophage inflammation via the Dectin1/Syk/CARD9/IRF5/NF‐κB pathway

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Background Inflammation plays an essential role in the pathogenesis of diabetic nephropathy (DN). Linderalactone (LNL), as a natural sesquiterpene lactone, has been discovered to have anti‐inflammatory activation. However, the effects of linderalactone on diabetes‐associated renal damage remain unclear.
Hao Chen   +7 more
wiley   +1 more source

Increase in soluble RAGE following intensive insulin therapy is associated with β‐cell functional improvement and glycemic remission in newly diagnosed type 2 diabetes

open access: yesJournal of Diabetes Investigation, EarlyView.
Short‐term intensive insulin therapy (SIIT) markedly increased circulating sRAGE levels in newly diagnosed type 2 diabetes. The magnitude of sRAGE elevation was associated with improved β‐cell function and a higher likelihood of short‐term glycemic remission.
Qimou Chen   +5 more
wiley   +1 more source

Achilles tenocytes from diabetic and non diabetic donors exposed to hyperglycemia respond differentially to inflammatory stimuli and stretch

open access: yesJournal of Anatomy, EarlyView.
Scheme depicting the experimental set up of the study. Achilles tendons and tenocytes were isolated from heterozygous (fa/+, non diabetic: non DMT2) and homozygous (fa/fa, diabetic: DMT2) Zucker Diabetic Fatty (ZDF) rats. Tendon degeneration, collagen type 1 alpha 1 chain (COL1A1) and alpha smooth muscle actin (αSMA) expression was determined in rat ...
Nils Fleischmann   +8 more
wiley   +1 more source

Advanced glycation end products and protein carbonyl levels in plasma reveal sex-specific differences in Parkinson's and Alzheimer's disease

open access: gold, 2020
Amit Sharma   +7 more
openalex   +1 more source

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