Results 171 to 180 of about 8,200,615 (297)

Combating ageing beyond the cell: Emerging roles of extracellular proteostasis

open access: yesThe FEBS Journal, EarlyView.
Ageing challenges the body's ability to maintain a stable and functional proteome, leading to protein damage and aggregation both inside and outside cells. This review focuses on the less well understood mechanisms of extracellular protein quality control and how they become disrupted in ageing, particularly in neurodegenerative diseases.
Siddharth R. Venkatesh   +7 more
wiley   +1 more source

Diagnostic and therapeutic significance of selected antibodies against advanced glycation end-products (anti-AGEs). [PDF]

open access: yesMol Biol Rep
Sobczyńska J   +6 more
europepmc   +1 more source

Hypertension among people living with HIV (PLHIV) compared with people without HIV (PWoH): A systematic review with meta‐analysis

open access: yesHIV Medicine, EarlyView.
Abstract Introduction Hypertension is a major cardiovascular risk factor and has increased among people living with HIV. However, evidence on its association with HIV status remains inconsistent. This systematic review aimed to assess the association between HIV status and hypertension and to examine, through subgroup analyses, whether this association
Mariene Garcia Gomes   +5 more
wiley   +1 more source

Periodontal Status of Type 1 Diabetes Mellitus and Healthy Pregnant Women: A Case–Control Pilot Study

open access: yesInternational Journal of Dental Hygiene, EarlyView.
ABSTRACT Aims This cross‐sectional ‘case–control’ pilot study aimed to compare the size of periodontal wounds, periodontal status and total inflammatory burden between pregnant women with type 1 diabetes mellitus (T1DM) and non‐diabetic pregnant women. Methods Fifteen T1DM pregnant women and 15 healthy pregnant women were included. Clinical parameters (
M. Janc   +4 more
wiley   +1 more source

Alteration of subgingival microbiome in patients with type 2 diabetes induced by diabetes treatment

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Aims/Introduction Diabetes and periodontal disease, a bacterial infection involving the oral microbiome, have a bidirectional relationship. However, the relationship between poor glycemic control and the oral microbiome remains unclear. The aim of this study was to assess the direct effect of intensive glycemic control on the oral microbiome ...
Moe Inoue   +13 more
wiley   +1 more source

Skin levels of advanced glycation end products in correlation with periodontal conditions - a pilot study. [PDF]

open access: yesBMC Oral Health
Cyris M   +8 more
europepmc   +1 more source

Effects of esaxerenone add‐on therapy versus angiotensin II receptor blocker dose escalation on albuminuria and blood pressure in hypertensive patients with type 2 diabetes: An exploratory randomized study

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Aims Residual albuminuria remains a major clinical challenge in patients with type 2 diabetes mellitus and hypertension despite renin–angiotensin system inhibitor therapy. Esaxerenone, a selective nonsteroidal mineralocorticoid receptor antagonist, reduces albuminuria; however, its effects on oxidative stress remain unclear.
Makoto Ohara   +9 more
wiley   +1 more source

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