Results 191 to 200 of about 8,200,615 (297)

Phloridzin Mitigates Aging‐Associated Periodontitis by Restraining Inflammatory Cell Death

Journal of Periodontal Research, EarlyView.
Phloridzin attenuated oxidative stressinduced senescence, inflammatory responses, and osteogenic dysfunction in HPDLCs. In an aging‐associated experimental periodontitis model, phloridzin alleviated alveolar bone loss, suggesting its potential to maintain periodontal tissue integrity under aging‐related inflammatory conditions.
Da Eun Lee, Eun‐Nam Kim, Gil‐Saeng Jeong   +2 more
wiley   +1 more source

Established and Emerging Biomarkers to Characterize Persons at Risk for Obesity—Paving the Way for Targeted Clinical Intervention Trials—A Comprehensive Position Paper

Obesity Reviews, EarlyView.
ABSTRACT Despite all efforts, obesity remains a major health concern worldwide, with continuously increasing rates, affecting approx. 14% of the total world population, being as high as 43% in some countries. As obesity is related to numerous comorbidities, including type 2 diabetes, cardiovascular diseases, and some types of cancer, the consequences ...
Farhad Vahid, Victoria Stopa, Laurent Malisoux, Yvan Devaux, Elsa Lamy, Fernando Capela e Silva, Sarah Forberger, Tiziana de Magistris, Antoni Sureda, Margalida Monserrat‐Mesquida, Maria Pérez‐Jiménez, Rajini Nagrani, Maria Giovanna Onorati, Michele Filippo Fontefrancesco, Jonathan Turner, Mahesh S. Desai, Josep Tur, Cristina Bouzas, Gino Gabriel Bonetti, Oliver Riedel, Gitte Ravn‐Haren, Rikke Andersen, Torsten Bohn   +22 more
wiley   +1 more source

Low-fat dietary pattern and dietary advanced glycation end-products intake: a secondary analysis of the Women's Health Initiative randomized trial. [PDF]

Br J Cancer
Pichardo MS, Hunt RP, Peterson LL, Pan K, Coday M, Jung SY, Snetselaar L, Neuhouser ML, Steck SE, Tabung FK, Saquib N, Manson JE, Chlebowski RT.   +12 more
europepmc   +1 more source

Plasmatic Profiling of Individuals With Combinations of Type 2 Diabetes Mellitus, Dyslipidemia and Periodontitis: A Cross‐Sectional Study

Oral Diseases, EarlyView.
ABSTRACT Aim The objective of this study was to investigate the global profile of plasmatic proteins of individuals affected simultaneously or not by type 2 diabetes mellitus (T2DM, well/poorly‐controlled), Dyslipidemia (DL), and Periodontitis (P). Methods Besides periodontal examination, plasma was collected for glycemic, and lipid analyses from 150 ...
François Isnaldo Dias Caldeira, Sâmia Cruz Tfaile Corbi, Alliny de Souza Bastos, Silvana Regina Perez Orrico, Cristiane Ribeiro Salmon, Yizhi Xiao, Walter Luiz Siqueira, Raquel Mantuaneli Scarel‐Caminaga   +7 more
wiley   +1 more source

Advanced Glycation End Products Upregulate Insulin Receptor Substrate-1 (IRS-1) in Human Cumulus Granulosa Cells. [PDF]

Cells
Merhi Z.
europepmc   +1 more source

Causal Effects of Type 2 Diabetes Mellitus on Chronic Periodontitis and the Mediating Role of Oxidative Stress: Evidence From Mendelian Randomization and Mediation Analysis

Oral Diseases, EarlyView.
ABSTRACT Background Type 2 diabetes mellitus (T2DM) is associated with an increased risk of chronic periodontitis, but genetic evidence and oxidative stress‐related pathways remain unclear. Objective This study assessed the genetically inferred association between T2DM and chronic periodontitis, evaluated oxidative stress biomarkers as potential ...
Mengjie Kong, James Kit Hon Tsoi, Kang Li, Cynthia Kar Yung Yiu   +3 more
wiley   +1 more source

Pyriphenone modification of glutaraldehyde pretreated bovine pericardium mitigates advanced glycation end products, calcification, and platelet adhesion. [PDF]

Acta Biomater
Zakharchenko A, Toomey NT, Alferiev I, Martinez A, Laurence D, Horyn O, Karim AM, Adamo A, Takano H, Nagaswami C, Stachelek SJ, Ferrari G, Levy RJ.   +12 more
europepmc   +1 more source

Osteoarthritis Therapeutics: From Microenvironment Understanding to Regenerative Intervention—Current Advances and Future Perspectives

Orthopaedic Surgery, EarlyView.
This article outlines a paradigm shift in OA therapeutics, OA as a systemic disease of joint microenvironment imbalance. It synthesizes advances in targeting key pathological hubs—immune, metabolic, and senescent—and details novel regenerative strategies using engineered biomaterials and exosomes.
Yongbiao Meng, Shenghua Wu, Quanchun Liu
wiley   +1 more source

Correlation Between Advanced Glycation End Products and Ultrasonographic Measurements of Cervico-Facial Skin Tissue. [PDF]

Diagnostics (Basel)
Babtan AM, Feurdean C, Vesa SC, Sabin O, Roşioară AI, Vlaicu SI, Macarie AE, Ilea A.   +7 more
europepmc   +1 more source

Role of Endogenous and Exogenous Phenolic Compounds on the Formation of Acrylamide and Fluorescent Advanced Glycation End Products in Heated Quinoa and Cañihua Flours. [PDF]

Foods
Aguilar-Galvez A, García-Ríos D, Quispe T, Ames C, Figueroa-Merma A, Chirinos R, Pedreschi F, Pedreschi R, Campos D.   +8 more
europepmc   +1 more source