Results 221 to 230 of about 91,166 (328)

Blockade of cannabinoid CB1 receptors potentiates the anti‐fibrotic effects mediated by SGLT2 inhibition in a mouse model of diabetic nephropathy

British Journal of Pharmacology, Volume 182, Issue 21, Page 5355-5377, November 2025.
Background and purpose Diabetic nephropathy (DN) is a common complication of diabetes. Current treatments include renin‐angiotensin‐aldosterone system (RAAS) blockers and sodium‐glucose co‐transporter 2 (SGLT2) inhibitors. The cannabinoid CB1 receptor is a potential therapeutic target.
Océane Pointeau, Awa Isma Ba, Audrey Geissler, Romain Barbosa, Abhishek Basu, Arif Muhammad, Marina Nivot, Maéva Loriot, Julia Leemput, Patricia Passilly‐Degrace, Sébastien Causse, Laurent Demizieux, Hélène François, Bruno Vergès, Jianmin Duan, Geneviève Gaucher, Michael Harvey, Pascal Degrace, Glenn Crater, Resat Cinar, Tony Jourdan   +20 more
wiley   +1 more source

A Simple Experimental Approach to Understanding the Formation of Advanced Glycation End Products. [PDF]

Cureus
Miyazaki K, Miyazaki K, Kaseda K.
europepmc   +1 more source

Up-regulated expression of the receptor for advanced glycation end products in cultured rat hepatic stellate cells during transdifferentiation to myofibroblasts [PDF]

, 2001
Heinz Fehrenbach, Ralf Weiskirchen, Michael Kasper, Axel M. Gressner   +3 more
openalex   +1 more source

The Role of Micronutrients in Atherosclerosis: Mechanisms and Clinical Application

Journal of Cellular and Molecular Medicine, Volume 29, Issue 21, November 2025.
ABSTRACT Micronutrients, though required in relatively small quantities by the human body, are essential for maintaining normal physiological functions and play a crucial role in the prevention and management of various diseases. Atherosclerosis (AS) is a common chronic inflammatory condition that often presents without obvious symptoms in its early ...
Yuxin Ouyang, Weiwei Jiang, Xiongquan Long, Peng Mao, Pingping He, Xinping Ouyang   +5 more
wiley   +1 more source

Non-invasive evaluation of advanced glycation end products in hair as early markers of diabetes and aging. [PDF]

Sci Rep
Kato S, Satoh Y, Okamoto A, Nagai R.
europepmc   +1 more source

Inhibition of nitric oxide synthase activity by early and advanced glycation end products in cultured rabbit proximal tubular epithelial cells

, 2000
Philippe Verbeke, Martine Perichon, Bertrand Friguet, Hilaire Bakala   +3 more
openalex   +1 more source

Albumin-derived advanced glycation end-products trigger the disruption of the vascular endothelial cadherin complex in cultured human and murine endothelial cells [PDF]

, 2001
Karel Otero, Fernando Martínez, Amada E Beltrán, Deyarina González, Beatriz HERRERA, Gypsy Quintero, René Delgado, Armando Rojas   +7 more
openalex   +1 more source

Exploring the Causal Relationship Between Blood Metabolites and Chronic Periodontitis: Insights From Genetic Causal Analysis

Journal of Cellular and Molecular Medicine, Volume 29, Issue 21, November 2025.
ABSTRACT To investigate the potential bidirectional causal relationship between specific blood metabolites and chronic periodontitis using Mendelian randomisation (MR). A two‐sample bidirectional MR analysis was conducted. Data on 1400 blood metabolites were obtained from a genome‐wide association study involving 8299 participants.
Weilun Cai, Huaxuan Zhao, Panpan Wang, Xiao Chen, Yumeng Yang, Hongle Wu, Zehao Chen, Fuchun Fang, Wei Qiu   +8 more
wiley   +1 more source

Effects of melatonin on advanced glycation end products, inflammation, and oxidative stress in peritoneal dialysis patients: a randomized controlled trial. [PDF]

Sci Rep
Movahedian M, Tabibi H, Atabak S, Hedayati M, Najafi I, Seyrafian S, Rouhani MH.   +6 more
europepmc   +1 more source

Improved Arterial Compliance by a Novel Advanced Glycation End-Product Crosslink Breaker [PDF]

, 2001
David A. Kass, Edward P. Shapiro, Miho Kawaguchi, Anne Capriotti, Angelo Scuteri, Robert C. deGroof, Edward G. Lakatta   +6 more
openalex   +1 more source