Results 101 to 110 of about 116,589 (255)

Advanced glycation end products, dementia, and diabetes [PDF]

Proceedings of the National Academy of Sciences, 2014
It is becoming abundantly clear that the insight into the pathological process of Alzheimer’s disease (AD) provided through autosomal dominant variants of the condition is only a partial one. The formation and aggregation of Aβ and the phosphorylation and aggregation of tau are clearly part of the core pathogenesis.
Simon, Lovestone, Ulf, Smith
openaire   +2 more sources

Vascular Effects of Dietary Advanced Glycation End Products

International Journal of Endocrinology, 2015
Evidence has accumulated lately demonstrating that advanced glycation end products (AGEs) play an important role in the development of diabetic and cardiovascular complications as well as the development of other chronic diseases.
Alin Stirban, Diethelm Tschöpe
doaj   +1 more source

Humoral factors in the formation of neuroosteoarthropathy in type 2 diabetes mellitus

Сахарный диабет, 2023
BACKGROUND: Diabetic neuroosteoarthropathy is a severe and insufficiently studied complication of diabetes mellitus, which is characterized by progressive destruction of bones and joints against the background of neuropathy and leads to the formation of ...
M. M. Kalandiya, E. A. Kogan, L. V. Nikankina, A. Y. Tokmakova, E. L. Zaitseva, G. R. Galstyan   +5 more
doaj   +1 more source

Selective disappearance of individuals with high levels of glycated haemoglobin in a free-living bird [PDF]

, 2016
This work was supported by the ANR (ANR-06-JCJC0082 to B.D.), the CNRS (PEPS INEE and PICS France–Switzerland to B.D.), the French Ministe`re de l’Enseignement Supe´rieur et de la Recherche (PhD fellowship to C.R.), the Re´gion Rhoˆne-Alpes (Explora’doc ...
Bize, Pierre, Cauchard, Laure, Doligez, Blandine, Récapet, Charlotte, Sibeaux, Adélaïde   +4 more
core   +3 more sources

Protective role of vitamin B6 (PLP) against DNA damage in Drosophila models of type 2 diabetes [PDF]

, 2018
Growing evidence shows that improper intake of vitamin B6 increases cancer risk and several studies indicate that diabetic patients have a higher risk of developing tumors.
MF Fenech, M Fenech, F Mitelman, A Aguilera, SF Bunting, SJ Duthie, MJ Shrubsole, YI Kim, JB Mason, CD Cantarella, R Percudani, R Percudani, ML Salvo di, H Hellmann, AA Booth, P Bilski, SA Denslow, BN Ames, L Galluzzi, S Mocellin, L Galluzzi, B Gylling, A Marzio, P Kanellis, SC Lee, M Brownlee, D Bonnefont-Rousselot, Y Hinokio, MT Goodarzi, E Tatsch, P Graham, RS Garofalo, RW Alfa, LP Musselman, SN Thompson, R Ugrankar, R Bohni, M Tatar, JM Murillo-Maldonado, M Lorenzi, A Rezabakhsh, SE Polo, JP Madigan, PA Jeggo, C Merigliano, H Vlassara, H Stopper, N Schupp, S Golbidi, EA Muellenbach, J Colombani, AT Haselton, SK Kim, G Lee, EJ Rulifson, SJ Broughton, T Ikeya, M Fraser, S Nakamura, M Pischetsrieder, S Nakamura, J Blasiak, PT Clayton, M Okada, JE Leklem, HJ Ahn, WA Nix, M Gatti, S Bonaccorsi, FJ Diaz-Benjumea   +69 more
core   +2 more sources

Dietary Advanced Glycation End Products: Digestion, Metabolism and Modulation of Gut Microbial Ecology

Nutrients, 2019
The formation of advanced glycation end products (AGEs) in foods is accelerated with heat treatment, particularly within foods that are cooked at high temperatures for long periods of time using dry heat.
M. Snelson, M. Coughlan
semanticscholar   +1 more source

Antiglycation Activity of Aucubin In Vitro and in Exogenous Methylglyoxal Injected Rats

Molecules, 2019
Advanced glycation end products (AGEs) is a causative factor of various chronic diseases, including chronic kidney disease and atherosclerosis. AGE inhibitors, such as aminoguanidine and pyridoxamine, have the therapeutic activities for reversing the ...
Eunsoo Jung, Su-Bin Park, Woo Kwon Jung, Hyung Rae Kim, Junghyun Kim   +4 more
doaj   +1 more source

The AGE receptor, OST48 drives podocyte foot process effacement and basement membrane expansion (alters structural composition)

Endocrinology, Diabetes & Metabolism, 2021
Aims The accumulation of advanced glycation end products is implicated in the development and progression of diabetic kidney disease. No study has examined whether stimulating advanced glycation clearance via receptor manipulation is reno‐protective in ...
Aowen Zhuang, Felicia Y. T. Yap, Danielle J. Borg, Domenica McCarthy, Amelia Fotheringham, Sherman Leung, Sally A. Penfold, Karly C. Sourris, Melinda T. Coughlan, Benjamin L. Schulz, Josephine M. Forbes   +10 more
doaj   +1 more source

Clearance kinetics and matrix binding partners of the receptor for advanced glycation end products [PDF]

, 2014
Elucidating the sites and mechanisms of sRAGE action in the healthy state is vital to better understand the biological importance of the receptor for advanced glycation end products (RAGE).
A Bierhaus, AL Miller, AM Schmidt, B Rippe, C Cheng, C Chuong, CN Pace, D Frommhold, DI Sternberg, DS Pisetsky, G Marsche, H Fehrenbach, H Vlassara, H Vlassara, H Zhang, HC Volz, J Brett, J Steiner, J Xie, Jan J. Enghild, JH Boyd, JL Wautier, JM Englert, JM Englert, JR Klune, Judson M. Englert, K Dahlin, K Kataoka, KC Sourris, Lasse Ramsgaard, Lauren T. Crum, LE Hanford, Louis J. Sparvero, M Neeper, M Shirasawa, MA Hofmann, Michael T. Lotze, MT Goova, N Demling, Neale S. Mason, P Andrews, P Teismann, Pavle S. Milutinovic, R Pullerits, R Ramasamy, RH Hastings, RH Hastings, RM Effros, S Du Yan, S Mizumoto, S Muhammad, S Zeng, T Do, T Wendt, TA John, Tim D. Oury, William R. Abrams, Y Abdiche, Z Sarkany   +58 more
core   +2 more sources

Advanced Glycation End Products, Soluble Receptor for Advanced Glycation End Products, and Risk of Colorectal Cancer [PDF]

Cancer Epidemiology, Biomarkers & Prevention, 2011
Abstract Background: Advanced glycation end products (AGE) accumulate in human tissue proteins during aging, particularly under hyperglycemia conditions. AGEs induce oxidative stress and inflammation via the receptor for AGEs (RAGE) and soluble RAGE (sRAGE) can neutralize the effects mediated by RAGE–ligand engagement ...
Li, Jiao, Philip R, Taylor, Stephanie J, Weinstein, Barry I, Graubard, Jarmo, Virtamo, Demetrius, Albanes, Rachael Z, Stolzenberg-Solomon   +6 more
openaire   +2 more sources