Results 81 to 90 of about 87,091 (210)
Journal of the Formosan Medical Association, 2015 Blockade of advanced glycation end-products (AGE) is able to reduce diabetic complications and control periodontitis. This study aimed to determine whether the application of aminoguanidine (AG), an AGE inhibitor, or N-phenacylthiazolium bromide (PTB ...
Sheng-Chueh Tsai +6 more
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Cells, 2021 Systemic lupus erythematosus (SLE) is characterized by abnormal action of the immune system and a state of chronic inflammation. The disease can cause life-threatening complications.
Agnieszka Nowak +5 more
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Advanced glycation end products, dementia, and diabetes [PDF]
Proceedings of the National Academy of Sciences, 2014 It is becoming abundantly clear that the insight into the pathological process of Alzheimer’s disease (AD) provided through autosomal dominant variants of the condition is only a partial one. The formation and aggregation of Aβ and the phosphorylation and aggregation of tau are clearly part of the core pathogenesis.
Simon, Lovestone, Ulf, Smith
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Advanced Glycation End Products in the Pathogenesis of Psoriasis [PDF]
International Journal of Molecular Sciences, 2017 Advanced glycation end products (AGEs) are extremely oxidant and biologically reactive compounds, which form through oxidation of sugars, lipids and amino acids to create aldehydes that bind covalently to proteins. AGEs formation and accumulation in human tissues is a physiological process during ageing but it is enhanced in case of persistent ...
Papagrigoraki, Anastasia +4 more
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Selective disappearance of individuals with high levels of glycated haemoglobin in a free-living bird [PDF]
, 2016 This work was supported by the ANR (ANR-06-JCJC0082 to B.D.), the CNRS (PEPS INEE and PICS France–Switzerland to B.D.), the French Ministe`re de l’Enseignement Supe´rieur et de la Recherche (PhD fellowship to C.R.), the Re´gion Rhoˆne-Alpes (Explora’doc ...
Bize, Pierre +4 more
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Role of advanced glycation end products in cellular signaling
Redox Biology, 2014 Improvements in health care and lifestyle have led to an elevated lifespan and increased focus on age-associated diseases, such as neurodegeneration, cardiovascular disease, frailty and arteriosclerosis.
Christiane Ott +5 more
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Advanced glycation end-products in diabetic nephropathy [PDF]
Nephrology Dialysis Transplantation, 1999 Throughout the industrialized (well-fed) world, diabetes mellitus is the most prevalent cause of end-stage renal disease (ESRD). Diabetic nephropathy is as likely to develop in long-duration non-insulin-dependent diabetes (type 2) as in insulin-dependent diabetes mellitus (type 1).
openaire +2 more sources
BiomedicinesBackground: Type 2 diabetes (T2DM) affects over 500 million people worldwide, and over 50% of this group experience the most common complication, diabetic peripheral neuropathy (DPN). The presence of advanced glycation end-products (AGEs) has been linked
Indumathi Singh +5 more
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Journal of Diabetes Investigation, 2019 Aims/Introduction Advanced glycation end‐products (AGEs), which are a major cause of diabetic vascular complications, accumulate in various tissues under chronic hyperglycemic conditions, as well as with aging in patients with diabetes.
Hiroyasu Mori +14 more
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Evaluation of the activity of the immune system and age-related tissue markers in Turquoise killifish \ud (Nothobranchius furzeri, Jubb 1971) \ud and their role in cell ageing\ud [PDF]
, 2010 Currently the Turquoise Killifish is considered the best animal model suitable for aging research. \ud This annual fish, from south east Africa, shows an exceptionally adaptive behaviour to dry periods: indeed, due to this extreme environmental ...
Di Cicco, Emiliano, Rossi, Giacomo
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