Results 101 to 110 of about 51,328 (260)
Glycation at the Crossroads of Disease Pathogenesis: Mechanistic Insights and Therapeutic Frontiers
DiseasesProtein glycation is a nonenzymatic modification that links sugar chemistry to molecular aging and chronic disease. Sequential reactions involving Schiff bases, Amadori products, and reactive α dicarbonyl intermediates generate advanced glycation end ...
Sneha Krishnamoorthi +2 more
doaj +1 more source
Precision Medical Sciences, EarlyView.Hyperglycemia‐driven cytokine activation initiates a sustained inflammatory cascade in diabetic kidney disease, promoting cellular injury and fibrogenic signaling. Integrating cytokine‐based biomarkers with risk stratification enables precision therapeutics that target inflammation and fibrosis, ultimately aiming to halt progression from early renal ...
Emmanuel Ifeanyi Obeagu
wiley +1 more source
Frontiers in MedicineDiabetes is a global health problem, with diabetic wounds constituting one of its most severe complications. Advanced glycation end products (AGEs) and their receptor, the receptor for advanced glycation end products (RAGE), play a key role in the ...
Haohui Lin +7 more
doaj +1 more source
Genomics and epigenomics of tissue repair: Implications for personalized medicine
Precision Medical Sciences, EarlyView.Genomic and epigenomic mechanisms govern tissue repair and regeneration through dynamic regulation of inflammation, cell fate, and extracellular matrix remodeling. The integration of multi‐omics, artificial intelligence, and precision regenerative therapies enables biomarker‐driven, personalized approaches to enhance healing and minimize fibrosis ...
Jharna Medhi +7 more
wiley +1 more source
Sex-specific differences of advanced glycation end products in diabetes
Nutrition & DiabetesAdvanced glycation end products (AGEs) are formed through non-enzymatic glycation reactions and accumulate in tissues, particularly under pathological conditions such as diabetes mellitus.
Michael Hellwig +5 more
doaj +1 more source
The Anti-AGEing and RAGEing Potential of Isothiocyanates
MoleculesIsothiocyanates (ITCs), found in edible plants such as cruciferous vegetables, are a group of reactive organo-sulfur phytochemicals produced by the hydrolysis of precursors known as glucosinolates.
Bradley A. Krisanits +3 more
doaj +1 more source
Preparation of advanced glycation end products in vitro [PDF]
Nephrology Dialysis Transplantation, 2007 Waanders, Femke +4 more
openaire +2 more sources
Phytotherapy Research, EarlyView.ABSTRACT Asthma affects 260–300 million people worldwide. About 20%–35% of patients use medicinal plants with their asthma medication, often without telling their clinicians. Disclosure rates are low; up to 42% of asthma outpatients use herbal products, with no records in their charts.
Emine Kocyigit +5 more
wiley +1 more source
Phytotherapy Research, EarlyView.Research landscape and mechanistic insights into natural medicines for Alzheimer's disease. ABSTRACT Natural medicines have been widely investigated for Alzheimer's disease (AD), but the development of this field and the relationship between bibliometric themes and experimental evidence remain insufficiently characterized.
Maoning Wang +8 more
wiley +1 more source
Guideline for the Detection of Advanced Glycation End Products
Food Safety and HealthAdvanced glycation end products (AGEs), stable products of nonenzymatic reactions between reducing sugars and biological macromolecules, are widely present in biological tissues and processed foods.
Chenxu Bao +6 more
doaj +1 more source