Results 71 to 80 of about 116,589 (255)
Molecular MedicineAdvanced glycation end products (AGEs) are a diverse range of compounds that are formed when free amino groups of proteins, lipids, and nucleic acids are carbonylated by reactive carbonyl species or glycosylated by reducing sugars.
Yanchi Chen +5 more
semanticscholar +1 more source
Tumor Biology, 2017 Receptor for advanced glycation end products and glyoxalase I metabolizing advanced glycation end product precursors may play important role in the pathogenesis and progression of cancer.
Petra Tesarova +3 more
doaj +1 more source
Do advanced glycation end products contribute to food allergy?
Frontiers in Allergy, 2023 Sugars can bind non-enzymatically to proteins, nucleic acids or lipids and form compounds called Advanced Glycation End Products (AGEs). Although AGEs can form in vivo, factors in the Western diet such as high amounts of added sugars, processing methods ...
P. K. Smith +4 more
doaj +1 more source
Elevated hemoglobin glycation index identify non-diabetic individuals at increased risk of kidney dysfunction [PDF]
, 2017 Hemoglobin glycation index (HGI), calculated as the difference between the observed value of HbA1 and the predicted HbA1c based on plasma glucose concentration, is a measure of the individual tendency toward non-enzymatic hemoglobin glycation which has ...
Andreozzi, F +6 more
core +2 more sources
Role of galectin-3 in bone cell differentiation, bone pathophysiology and vascular osteogenesis [PDF]
, 2017 Galectin-3 is expressed in various tissues, including the bone, where it is considered a marker of chondrogenic and osteogenic cell lineages. Galectin-3 protein was found to be increased in the differentiated chondrocytes of the metaphyseal plate ...
Fantauzzi, Claudia Blasetti +3 more
core +5 more sources
Advanced Glycation End Products and Oxidative Stress in Type 2 Diabetes Mellitus
Biomolecules, 2015 Type 2 diabetes mellitus (T2DM) is a very complex and multifactorial metabolic disease characterized by insulin resistance and β cell failure leading to elevated blood glucose levels.
K. Nowotny +4 more
semanticscholar +1 more source
Frontiers in Cardiovascular Medicine, 2020 Obesity and diabetes are leading causes of cardiovascular morbidity and mortality. Although extensive strides have been made in the treatments for non-diabetic atherosclerosis and its complications, for patients with diabetes, these therapies provide ...
Lander Egaña-Gorroño +8 more
semanticscholar +1 more source
Advanced Glycation End Products: New Clinical and Molecular Perspectives
International Journal of Environmental Research and Public Health, 2021 Diabetes mellitus (DM) is considered one of the most massive epidemics of the twenty-first century due to its high mortality rates caused mainly due to its complications; therefore, the early identification of such complications becomes a race against ...
J. Salazar +12 more
semanticscholar +1 more source
Evaluation of the AGE/sRAGE Axis in Patients with Multiple Myeloma
Antioxidants, 2019 Glycative stress influences tumor progression. The aim of the present study was to evaluate the advanced glycation end products/soluble receptor of advanced glycation end products (AGE/sRAGE) axis in patients with multiple myeloma (MM).
Alessandro Allegra +10 more
doaj +1 more source
Impact of intracellular toxic advanced glycation end-products (TAGE) on murine myoblast cell death
Diabetology & Metabolic Syndrome, 2020 Background Sarcopenia is a progressive condition that is characterized by decreases in skeletal muscle mass and function. Although sarcopenia is associated with lifestyle-related diseases (LSRD), the mechanisms underlying cell death in myoblasts, which ...
Takanobu Takata +2 more
doaj +1 more source