Results 31 to 40 of about 585,342 (345)

Adverse drug reaction and organ damage: the liver [PDF]

, 2016
Drug-induced liver injury (Dili) is among the most challenging acute or chronic liver conditions to be handled by physicians. Despite its low incidence in the general population, Dili is a frequent cause of acute liver failure.
LICATA, Anna
core   +1 more source

A clinical study of morphological patterns of cutaneous adverse drug reaction and its causality assessment in tertiary care hospital of central India [PDF]

, 2020
Background: Adverse reactions to drugs are as old as drug. Cutaneous adverse drug reactions are the most common type of drug reaction. Most cutaneous adverse drug reactions are important as they are frequently the reason for discontinuation of drug ...
Shende, Tanaji R., Siddiqui, Riyaz A.
core   +2 more sources

Adverse drug reactions to tocolytic treatment for preterm labour: Prospective cohort study [PDF]

, 2009
Objective To evaluate the incidence of serious maternal complications after the use of various tocolytic drugs for the treatment of preterm labour in routine clinical situations. Design Prospective cohort study.
Duvekot, J.J. (Hans), Erwich, J.J.H.M., Famschobben, F., Geijn, H.P. (Herman) van, Gyselaers, W.J. (Wilfried), Hanssens, M. (Myriam), Harmark, L. (Linda), Heus, R. (Roel) de, Holsbeke, C.D. (Caroline) van, Mol, B.W.J. (Ben), Visser, G.H. (Gerhard Henk), Wolf, H. (Hans Uwe)   +11 more
core   +1 more source

Idiopathic non-histaminergic acquired angioedema: a case series and discussion of published clinical trials

Clinical and Translational Allergy, 2017
Background Idiopathic non-histaminergic acquired angioedema (InH-AAE) is a rare disease for which there are no available laboratory parameters to clearly define the disorder. Therapy is often difficult and various treatment options have been proposed. In
Martin Christian Bucher, Tatjana Petkovic, Arthur Helbling, Urs Christian Steiner   +3 more
doaj   +1 more source

MRGPRX2 and Adverse Drug Reactions [PDF]

Frontiers in Immunology, 2021
Many adverse reactions to therapeutic drugs appear to be allergic in nature, and are thought to be triggered by patient-specific Immunoglobulin E (IgE) antibodies that recognize the drug molecules and form complexes with them that activate mast cells. However, in recent years another mechanism has been proposed, in which some drugs closely associated ...
openaire   +4 more sources

Value of patch tests in clindamycin-related drug eruptions [PDF]

, 2011
Background. Patch tests help to confirm the aetiology of the cutaneous adverse drug reactions involving delayed hypersensitivity mechanisms, but the results vary with the pattern of skin reaction and the culprit drug. Objectives.
Brites, MM, Canelas, MM, Gonçalo, Margarida, Pereira, N, Santiago, F   +4 more
core   +1 more source

Irisin Is Controlled by Farnesoid X Receptor and Regulates Cholesterol Homeostasis

Frontiers in Pharmacology, 2019
ObjectiveThe aim of this study was to investigate whether the nuclear receptor farnesoid X receptor (FXR) could regulate FNDC5/Irisin expression and the role of Irisin in hyperlipidemia and atherosclerosis in ApoE-/- mice.Methods and ResultsWe treated ...
Hong Li, Hong Li, Jing Shen, Jing Shen, Tong Wu, Tong Wu, Jiangying Kuang, Jiangying Kuang, Qinhui Liu, Shihai Cheng, Shihai Cheng, Shiyun Pu, Shiyun Pu, Lei Chen, Lei Chen, Rui Li, Rui Li, Yanping Li, Yanping Li, Min Zou, Zhiyong Zhang, Wei Jiang, Aijuan Qu, Jinhan He, Jinhan He   +24 more
doaj   +1 more source

Efficacy of a Modified Sepsis System on the Mortality Rate of Septic Shock Patients in the Emergency Department of Siriraj Hospital

Journal of Health Science and Medical Research (JHSMR), 2022
Objective: To compare the 28-day mortality rate between pre- and post-implementation of a modified sepsis fast-track system. Material and Methods: A cross-sectional cohort study was conducted at the Emergency Room (ER) of Siriraj Hospital, Bangkok.
Natvadee Rakpraisuthepsiri, Usapan Surabenjawong, Chok Limsuwat, Ploylarp Lertvipapath   +3 more
doaj   +1 more source

Learning lessons from adverse drug reactions in children [PDF]

, 2016
Drug toxicity is, unfortunately, a significant problem in children both in the hospital and in the community. Drug toxicity in children is different to that seen in adults.
Bodenstein, Bénard-Laribière, Giménez, Kearns, Phelps, Silverman, Starko, Zhang   +7 more
core   +2 more sources

Association between HLA-B Alleles and Carbamazepine-Induced Maculopapular Exanthema and Severe Cutaneous Reactions in Thai Patients

Journal of Immunology Research, 2018
The HLA-B∗15:02 allele has been reported to have a strong association with carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) in Thai patients.
Chonlaphat Sukasem, Chonlawat Chaichan, Thapanat Nakkrut, Patompong Satapornpong, Kanoot Jaruthamsophon, Thawinee Jantararoungtong, Napatrupron Koomdee, Suthida Sririttha, Sadeep Medhasi, Sarawut Oo-Puthinan, Ticha Rerkpattanapipat, Jettanong Klaewsongkram, Pawinee Rerknimitr, Papapit Tuchinda, Leena Chularojanamontri, Napatra Tovanabutra, Apichaya Puangpetch, Wichai Aekplakorn   +17 more
doaj   +1 more source