Results 111 to 120 of about 7,475 (210)

Deciphering the relative importance of genetic elements in hypervirulent Klebsiella pneumoniae to guide countermeasure developmentResearch in context

EBioMedicine
Summary: Background: Quantitating the contribution of phenotype-responsible elements in hypervirulent Klebsiella pneumoniae is needed. Methods: Isogenic mutants of four hypervirulent clinical isolates that produced K1 (ST23), K2 (ST86), K20 (ST1544), or
Thomas A. Russo, Ulrike Carlino-MacDonald, Zachary J. Drayer, Connor J. Davies, Cassandra L. Alvarado, Alan Hutson, Ting L. Luo, Melissa J. Martin, Patrick T. McGann, Francois Lebreton   +9 more
doaj   +1 more source

Egy új citotoxinnak, cytholethalis distending toxinnak (CDT) magyarországi előfordulása és molekulárbiológiai jellemzése = The occurrence and molecular biological characterization of a new cytotoxin -cytolethal distending toxin (CDT)- in Hungary [PDF]

, 2006
Jelen pályázatunkban egy új és nagy jelentőséggel rendelkező bakteriális citotoxin családnak a cytolethalis duzzasztó (distending) toxinnak (CDT) a magyarországi elterjedését és molekuláris biológiai jellemzését végezve megállapítottuk, hogy a CDT ...
Fekete, Péter Zsolt, Hywell, Ball, Mohamed, A. Dow, Nagy, Béla, Tóth, István   +4 more
core  

The stress-responsive Hsp90 chaperone is required for the production of the genotoxin colibactin and the siderophore yersiniabactin by Escherichia coli [PDF]

, 2016
The genotoxin colibactin synthesized by Escherichia coli is a secondary metabolite belonging to the chemical family of hybrid polyketide/non-ribosomal peptide compounds.
Brachmann, AO, Dozois, CM, Garcie, C, Garénaux, A, Genevaux, P, Houle, S, Martin, P, McCarthy, AJ, Nougayrède, JP, Oswald, E, Piel, J, Pénary, M, Taylor, PW, Tronnet, S   +13 more
core  

Analysis of the Type VI secretion system and microbiological characteristics of hypervirulent Klebsiella pneumoniae causing urinary tract infections

Journal of Infection in Developing Countries
Introduction: This study aimed to evaluate the Type VI secretion system (T6SS) and microbiological features in hypervirulent Klebsiella pneumoniae (hvKP) causing urinary tract infections (UTIs) in hospitalized adults.
Fei-Fei Li, Jing-Jing Li, Yin Zhang, Zhi-Yu Wu, Yuan-Hong Xu   +4 more
doaj   +3 more sources

Complete genome and comparative genomic analysis of cefpodoxime resistant Pantoea septica strain GABEPS69 isolated from saliva of a patient diagnosed with treatment resistant schizophrenia

International Journal of Medical Microbiology
Objectives: This study aims to generate the first complete genome of Pantoea septica and provide a thorough genomic characterisation of this under-documented species. The study seeks to enhance understanding of P. septica, clarifying features relevant to
Francesca McDonagh, Aneta Kovarova, Anna Tumeo, Andy O’Connor, Niamh McEvoy, Aneesa Mangalam Lonappan, Kasthuri Venkateswaran, Elaine K. Murray, Brian Hallahan, Georgios Miliotis   +9 more
doaj   +1 more source

Emergence of blaKPC-71 variant and loss of aerobactin-encoding genes (iucABCD-iutA) in ST11-K64 carbapenem-resistant Klebsiella pneumoniae during ceftazidime–avibactam treatment

Journal of Global Antimicrobial Resistance
Objective: To investigate the within-host evolutionary dynamics of resistance and virulence in carbapenem-resistant Klebsiella pneumoniae during ceftazidime-avibactam treatment. Methods: Three K.
Fang-ling Du, Dan-dan Wei, Yong-qing Guo, Peng Liu, Yan-fang Mei, Shan-shan Huang, Qi-sen Huang, Lin-Ping Fan, Yang Liu   +8 more
doaj   +1 more source

Clonal Relationships among Blood-Stream Isolates of Escherichia coli [PDF]

, 1995
The clonal relationships among 187 bloodstream isolates of Escherichia coli from 179 patients at Boston, Mass., Long Beach, Calif., and Nairobi, Kenya, were determined by multilocus enzyme electrophoresis (MLEE), analysis of polymorphisms associated with
Maslow, Joel N., Whittam, Thomas S., Gilks, Charles F., Wilson, Richard A., Mulligan, Maury Ellis, Adams, Kenneth S., Arbeit, Robert D.   +6 more
core  

Genotyping of Virulence Factors of Uropathogenic Escherichia coli by PCR

Novelty in Biomedicine, 2015
Background: Escherichia coli is the most causative agent of urinary tract infections (UTIs). Apart from all human infectious diseases, UTI have a high prevalence and in most cases, Escherichia coli is a dominance bacterium which can cause pyelonephritis ...
Hamid Reza Jalali, Ali Pourbakhsh, Fatemeh Fallah, Gita Eslami   +3 more
doaj  

Spontaneous phenotypic suppression of GacA-defective Vibrio fischeri is achieved via mutation of csrA and ihfA [PDF]

, 2015
Background: Symbiosis defective GacA-mutant derivatives of Vibrio fischeri are growth impaired thereby creating a selective advantage for growth-enhanced spontaneous suppressors. Suppressors were isolated and characterized for effects of the mutations on
Avitabile, Ashley, Ballok, Alicia E., Foxall, Randi L., Whistler, Cheryl A.   +3 more
core   +1 more source

Phylogenetic group, antibiotic resistance, virulence gene, and genetic diversity of Escherichia coli causing bloodstream infections in Iran

Frontiers in Microbiology
Escherichia coli is one of the most important pathogens causing bloodstream infections (BSIs) throughout the world. We sought to characterize the phylogroup classification, major human sequence types (STs), antimicrobial resistance, presence of selected ...
Saeed Hemati, Shahnaz Halimi, Fereshteh Jabalameli, Mohammad Emaneini, Reza Beigverdi   +4 more
doaj   +1 more source